Prep the burn unit

Jen Bendery@jbendery.bsky.social · 17h ago

oh man 😂

We have an open Call for PhD positions at the Max Planck Institute for Evolutionary Anthropology in Leipzig @mpi-eva-leipzig.bsky.social : www.leipzig-school.eva.mpg.de/application/... #adna #phd

Open positions - Max Planck Institute for Evolutionary Anthropology

leipzig-school.eva.mpg.de

Extract: Purdue University seeks an Assistant/Associate Professor in Basic Medical Sciences focusing on One Health. Candidates should have a Ph.D. and relevant post-doctoral experience, with a commitment to research, teaching, and interdisciplinary collaboration.

Phylogenetic conservation scores have long been used to identify selection targets in the genome. With machine learning, they take a new form and will likely grow in popularity. @apragsdale.bsky.social and I investigate their relationship with mutation rates www.biorxiv.org/content/10.6...

Strong correlations between mutation rates and selective constraint in the human genome?

The 21st century has seen repeated challenges to the premise that de novo mutations occur independently from their fitness effects. So far, these attempts have been dismissed as technical artifacts, r...

biorxiv.org

I'm excited to finally publish my postdoctoral work in @ajhgnews.bsky.social! This work was motivated by two big mysteries in autism research: 1) where and what are the undiscovered genetic components of autism, and 2) why are males diagnosed with autism more frequently than females?

The American Journal of Human Genetics@ajhgnews.bsky.social · 4d ago

🧬New from @rmschu.bsky.social & co! 📄A massively parallel reporter assay of MECP2cis-regulatory elements reveals genetic candidates for male-biased autism

Hello World ! Its pre-print time ! Awesome collaboration led by Michel Cohen-Tannoudji (not on Bsky) and the one and only @deborahbourchis.bsky.social. #BFF We solved the molecular mechanism underlying a mysterious hybrid incompatibility in mice: the DDK syndrome. 🧵🍿 www.biorxiv.org/content/10.6...

Transposable Element insertions Repurpose Immune Endonucleases as Drivers of Reproductive Isolation in Mice

The emergence of reproductive barriers between closely related populations is a fundamental step in speciation, yet the underlying genetic mechanisms remain poorly understood in mammals. Here we resol...

biorxiv.org

Johns Hopkins Biology is hiring a tenure-track Assistant Professor in computational genetics and genomics. Applications due Nov. 8th: apply.interfolio.com/194924 In my experience, this has been an incredibly supportive environment to build a lab. Please feel free to reach out with any questions.

rip to one of the coolest software engineers who ever lived

We studied the evolution of genome-wide linkage disequilibrium and its influence on genetic architecture with genetic drift. We found that the Bulmer effect is population size and demography dependent. For nerds: genetic architecture follows from solving PDEs.

bioRxiv Genetics@biorxiv-genetic.bsky.social · 7d ago

Linkage disequilibrium moderates how evolving genetic background shapes variant-level architecture https://www.biorxiv.org/content/10.64898/2026.10.01.756092v1

Excited to share that my department has an open faculty search for an Assistant Professor! The search is broad, focused on candidates who plan to address fundamental questions in genetics and genomics. The due date is soon: Nov 13. You can apply through interfolio. apply.interfolio.com/190644

I'm hiring a postdoc in population and evolutionary genetics at Indiana University Bloomington! We're a computational lab working on spatial demographic inference using genomic data and machine learning. You can apply here: indiana.peopleadmin.com/postings/34508

I think administrators cowing to media pressure hurts the reputation of a university much more than piloting a long overdue and quite modest change to grading practices.

Shea Vance@sheatvance.bsky.social · 2w ago

NEW: U. Mich is pumping the brakes on its plan to pass/fail first-semester freshmen in one of its colleges. The president wrote to admins that "distorted" media coverage of the plan could hurt the reputations of the university and its students. For @chronicle.com: www.chronicle.com/article/u-of...

Join us through the Presidential Postdoctoral Fellowship in EEB! Conduct your own research, mentored by 2+ EEB faculty. $65k salary + research/moving $. All areas of EEB welcome. Apply by 11/1 I co-chair this search and am happy to field questions Spread the word! eeb.msu.edu/initiatives/...

Postdoctoral Fellowship - Ecology, Evolution, and Behavior

eeb.msu.edu

Today I went deep into Michigan's run game issues in the 1st half. Short version: I think defenses are triggering off motion to stop Beck's favorite stuff (Jet opposite QB power). The good news is he adjusted. mgoblog.com/content/neck...

Neck Sharpies: Don't Slash My Jet Bash

Why was the second half run game better than the first half run game?

mgoblog.com

Humans are reading ChatGPT users’ prompts to improve OpenAI’s models, and those chats can include sensitive, personal information, according to leaked internal documents and real prompts seen by 404 Media. www.404media.co/inside-proje...

Inside ‘Project Lily’: The Humans Reading Your ChatGPT Chats

Humans are reading ChatGPT users’ prompts to improve OpenAI’s models, and those chats can include sensitive, personal information, according to leaked internal documents and real prompts seen by 404…

404media.co

What can we learn about a single rare variant? Published today in Science: the 23andMe Research Institute and Dana-Farber studied the EGFR T790M in 10.1M 23andMe research participants. The variant has OR = 25.2 for lung cancer, rising to 61.7 in never-smokers(!). 🧵

Infertility affects ~1 in 6 people, and up to 30% of cases are unexplained. I am excited to present my postdoctoral work from @toddmacfarlan.bsky.social 's lab, now available as a preprint: tinyurl.com/yync6f2r addressing a possible role for the meiotic gene PRDM9 in infertility 🧵/1

This is a very cool study I have written about for @newscientist.com Adult chimpanzees have been observed passing tools to their younger relatives, helping them learn the skills needed for fishing for ants or algae 🧪 www.newscientist.com/article/2589...

Wild chimpanzees teach youngsters by handing them tools | New Scientist

Adult chimpanzees have been observed passing tools to their younger relatives, helping them learn the skills needed for fishing for ants or algae

newscientist.com

The Carlson Lab at the University of Rochester is recruiting researchers at all levels! Please reach out to Maryn (marync.github.io/carlsonlab/i...) if you are interested in groundbreaking problems in population and quantitative genetics. Maryn is brilliant and will be a great mentor!

I am excited to share that I will be joining the Baker Institute for Animal Health and College of Veterinary Medicine at Cornell University as an Assistant Professor next spring! I am grateful to my mentors and colleagues who have supported me throughout this journey.

Please repost: My department (quantitative and computational biology at the University of Southern California) is hiring a teaching-track faculty member. The new hire will focus on teaching statistics courses to biology students. Apply by Dec 1 usccareers.usc.edu/job/los-ange...

This is a very nice review article from @pontus-skoglund.bsky.social and @mathiesoniain.bsky.social . Figure 2 gives a very nice summary of the different ways selection tests are calibrated. They also offer 5 succinct summaries of the current state of the field for humans.

Nature Reviews Genetics@natrevgenet.nature.com · last mo.

New online! Genomic insights into natural selection in recent human history

New online! Genomic insights into natural selection in recent human history

Genomic insights into natural selection in recent human history

Nature Reviews Genetics, Published online: 11 September 2026; doi:10.1038/s41576-026-01010-9Advances in genome-wide selection scans and ancient DNA have greatly expanded our ability to study human evolution. This Review discusses the conceptual and statistical challenges in identifying and interpreting selection signals, and how recent approaches are reshaping our understanding of human evolution over the past 10,000 years.

dlvr.it

How & why does the distribution of fitness effects #DFE vary among species? Meixi Lin, @klohmueller.bsky.social &co analyze genetic variation from 11 animal species, finding that fitness effects are influenced by phylogeny, population size, & organismal complexity @plosbiology.org 🧪 buff.ly/t5q7Mqo

I’m looking to hire an NIH funded postdoc to join our lab here at Davis (please RT). Ongoing areas of interest include: 1) polygenic signals of selection from time series, ARGs, GWAS, etc 2) The interpretation of GWAS, polygenic scores, & sources of confounding

Barking Up Inferred Trees: Detecting Signatures of Selection in Dog Genomes Using Ancestral Recombination Graphs https://www.biorxiv.org/content/10.64898/2026.09.02.748875v1

I am delighted to announce that The Department of Human Genetics at the University of Utah is continuing a multi-year recruiting initiative for multiple tenure-track faculty positions at the rank of Assistant Professor. Please share and consider applying! utah.peopleadmin.com/postings/208...

'"At the end of the day ... they're either going to play for you or they're going to play for someone else around the country," Kiffin said at a news conference Monday. "So we've made the decision to recruit them like probably most people are."' - This is exactly what I hear peers say about using AI

Let's talk about AOC as a young scientist & her award winning research on antioxidants & C. elegans, a standard roundworm model. She grew up in the Bronx. Ethnically Puerto Rican, her dad Sergio, an architect, died when she was 19. Her mother cleaned houses, drove a school bus. Working class.

Alex Merz 🇺🇸🇨🇦🇺🇦@merz.bsky.social · 2mo ago

People just don't realize how smart AOC is. She came in second at the national Intel Science and Engineering Fair. An *incredibly* competitive field. That's roughly equivalent to being the second best forward in high school basketball in the United States.

Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...