Jorge Barrasa Fano
@barrasa-fano.bsky.social
Postdoc at Computational Biology lab @VIB | Mechanobiology & Regulatory genomics ScienceCommunication coordinator at cebebelgica.es/en_GB/
Celebrating 30 years of VIB today, and we have plenty of ideas about what comes next. VIB.AI took the stage as a model built across centers, with affiliated PIs, and supported by the VIB Data Core and VIB AI Studio. Niklas Kempynck brought the science with a fantastic talk.
I've always wanted to see a total eclipse. But it was so much better than I ever imagined. We went to Mallorca. We walked a lot. Found a perfect little spot. Read Annie Dillard's wonderful essay 'Total Eclipse' as we waited. Saw the total eclipse (with some clouds right at the end). Magic.
Juicing out being in Glasgow for a conference, I managed to escape for a few minutes to go to @waterstones.bsky.social at Byres Road to get @andreawulf.bsky.social 's new book!😍😍
Hello, Yesterday I presented my postdoc work at SynSci — Synergy for Science 2026 in Glasgow, in a humongous screen. A perfect platform for my last dance as a Traction Force Microscopy person 💜
What's going to happen in the future and when? A timeline of the far future. 🧪
Timeline of the far future - Wikipedia
en.wikipedia.org
Our June issue is here! rupress.org/jcb/issue/22... The cover shows a maximum intensity projection from a confocal image stack showing an angiogenic sprout emerging from an engineered microvessel. From @lakynm.bsky.social et al. of the Matthew Kutys lab: rupress.org/jcb/article/... #Cytoskeleton
“Books are like seeds. They can lie dormant for centuries and then flower in the most unpromising soil.” — Carl Sagan
I am super happy to say that @fwovlaanderen.bsky.social will fund my next 3 years of research as a senior postdoc!! I will be moving to @steinaerts.bsky.social lab. I'm very excited for this new adventure! I'll start on October 1st!😍
All you ever wanted to know about how to analyse the nematic nature of cellular tissues is right here 👀👇🏼! Bonus #1: we did it for many cell types and uncovered unexpected defect behavior 🐌 Bonus #2: for theoreticians looking for parameter values for your simulation🧑🏼💻 tinyurl.com/2s399yen
Just published in @science.org 🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials! www.science.org/doi/10.1126/...
Science | AAAS
science.org
Pau Guillamat@pauguillamat.bsky.social · last yr.New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering
Precioso. Dos seres humanos contemplando la Tierra mientras viajan a la Luna.
🎙️El otro día comenté en Radioalma el artículo en #NatureAstronomy sobre el juego completo de nucleobases en el asteroide #Ryugu, pero en realidad fue una excusa para poder hablar del ADN. 🎧👇🏽 (#CEBE en las ondas) open.spotify.com/episode/0pME...
CEBE en las ondas: ADN, ARN y un asteroide que nos acerca al origen de la vida
open.spotify.com
Our first cancer biology preprint is up! TRIM9 switches melanoma cell phenotypes. First author @klukasik.bsky.social has taken the lab into new directions for sure in a fun collaboration with @coronin.bsky.social. We can't wait to hear what you think. www.biorxiv.org/content/10.6...
biorxiv.org
Check out my contribution to the wonderful threads posted by @epimechfc.bsky.social !! In this one I talk about #3DTFM! 👇
epithelial mechanics fan club@epimechfc.bsky.social · 8mo agoWe had covered the history of traction force microscopy (TFM) earlier: bsky.app/profile/epim... But what about applying TFM into more physiologically relevant systems, such as those in 3D? I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.
📰 Check out our new paper published in Nature Protocols @natureportfolio.nature.com !! Great work by Apeksha Shapeti and Janne de Jong, in which they explain everything you need to know to perform 3D traction force microscopy on multicellular systems!! www.nature.com/articles/s41... (1/3)
Investigation of mechanical forces during multicellular early angiogenic sprouting by three-dimensional traction force microscopy in hydrogel matrices - Nature Protocols
Investigating mechanical forces during angiogenic sprouting by three-dimensional traction force microscopy (TFM) in hydrogel matrices, including steps to analyze and interpret cell–extracellular matri...
nature.com
🚨 Ayúdanos a elegir los mejores libros de divulgación en español! Como cada año, Científicos Españoles en Bélgica #CEBE , lanzamos nuestro concurso anual #CienciaConÑ !! 📚Hemos abierto las propuestas para posibles candidatos! Puedes proponer todos los que quieras!👇 forms.gle/qdVYeCSdgsr6...
8.5 years ago my friend @apek-shapeti.bsky.social told me that the Mechanobiology and Tissue Engineering Lab at KU Leuven, where she was about to start her PhD, was looking for someone with an image analysis profile...
Paper alert! 💻 How many cells do you need to train reliable deep learning models in regulatory genomics? We asked how data quality, sequencing depth, and dataset size affect training of sequence-to-function models from scATAC-seq. Out now www.nature.com/articles/s41... (details below)
Evaluating single-cell ATAC-seq atlasing technologies using sequence-to-function modeling - Nature Communications
Generating high-quality training data for machine learning is costly. Here, authors include sequence-to-function modeling in benchmarking of custom and commercial droplet-based scATAC platforms, and r...
nature.com
📝Check out our latest paper published in @commsbio.nature.com !! Great work by Samet Aytekin and Laurens Kimps in this collaboration with @rochalab.bsky.social where they combined simultaneous FRET tension sensors and traction force microscopy! 👇🏽 www.nature.com/articles/s42...
Linking molecular tension and cellular tractions: a multiscale approach to focal adhesion mechanics - Communications Biology
Simultaneous mapping of tractions and molecular tension reveals how cells coordinate forces across scales, from whole-cell mechanics to polarized force transmission within individual focal adhesions.
nature.com
@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social www.biorxiv.org/content/10.6...
Check out our latest paper in Acta Biomaterialia!! Excellent work by my colleagues Nele Vaes and Maxim Vovchenko on chondrocytes and #mechanobiology of #OA ! 👇 www.sciencedirect.com/science/arti... This is the first #3DTFM on chondrocytes! Initially, we thought they wouldn't do much but...👀
Osteoarthritic chondrocytes exert higher contractile forces and exhibit enhanced protrusive activity when cultured in 3D degradable hydrogels
Osteoarthritis (OA) induces phenotypic changes in chondrocytes as well as alterations in matrix composition and mechanics. Yet, its impact on active c…
sciencedirect.com
Our paper describing the development of ShapeSpaceExplorer is now out: journals.plos.org/ploscompbiol... The software and documentation is available here: github.com/cmcb-warwick... Explainer thread below.
Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics
Biophysics of organoids
In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...
dlvr.it
A Perspective on 3D traction force microscopy provides practical experimental and computational guidance for users. @barrasa-fano.bsky.social www.nature.com/articles/s41...
Guidance for 3D traction force microscopy today and in the next decade - Nature Methods
This Perspective envisions the future of 3DTFM and provides practical guidelines for experimental and computation strategies for its application.
nature.com
I'm very happy to share my first article as a corresponding author published in @natmethods.nature.com !! 😍 Some groups (like us) have developed complex 3DTFM methods in the last 15 years. BUT its usage in studies that help better understand disease or development has been almost non-existent.
🫶 Muchas gracias @hectorsocas.bsky.social por tus palabras al principio del episodio de hoy de Coffee Break. open.spotify.com/episode/6h0P... Fue un verdadero placer conoceros a @conchilillo.bsky.social y a tí en el evento de divulgación científica que organizamos en CEBE el pasado lunes.
