Mattia Chini
@mattiachini.bsky.social
Studying how the brain develops https://www.chinilab.com/
First Neuropixels 2.0 recording in the new lab! 🚀🚀🚀 Look at that beautiful PFC spiking like crazy (for a neonatal mouse) 😍 This would have never been possible without the two amazing (bskyless) postdocs who helped setting up the rig and did the recording: Mercedes Hildebrandt and Davide Warm! 👏
Our paper "Neural timescales from a computational perspective" is finally out in @natneuro.nature.com: www.nature.com/articles/s41... We discuss how computational models and methods can distill empirical observations on neural timescales into quantitative, testable theories of brain computation.
Neural timescales from a computational perspective - Nature Neuroscience
This review integrates computational approaches to provide a unified view on how data analysis methods, biophysical mechanistic models and machine learning approaches can help to uncover the origins a...
nature.com
Only few spots remain! #FENS2026
Liset M. de la Prida@lmprida.bsky.social · 4mo agoA must-needed benchmarking👇🏼 How much is methodological and how much is conceptual? A reason for us developing #rippl-AI github.com/PridaLab/rip... Don’t miss the next hackathon avant-FENS pre-fens-brainhack.github.io/brainhack2026/ with @acnavasolive.bsky.social & @mattiachini.bsky.social
Differences stemmed from the way researchers defined concepts, to the algorithms they used to analyze the data, to the parameters they employed when implementing the algorithms, note @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
18 teams analyzed a neuro dataset and got different answers
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
thetransmitter.org
Sounds bad. Also: "where careers depend on novel, significant findings, the same flexibility that produced innocent disagreement at a hackathon has far greater consequences. A researcher who needs a small p-value to complete a story may be swayed by an analytical pipeline that delivers it"
The Transmitter @thetransmitter.bsky.social · 4mo agoDifferences stemmed from the way researchers defined concepts, to the algorithms they used to analyze the data, to the parameters they employed when implementing the algorithms, note @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
So, even in #electrophysiology, where data are often treated as “hard”, substantial disagreement can occur. They too depend on definitions, thresholds, preprocessing & assumptions. 🧵1/2
The Transmitter @thetransmitter.bsky.social · 4mo agoA hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
We're organizing a full-day Neuro-AI workshop at OHBM with a 90-minute-long hands-on session to cover all the nitty-gritty of it. If you're around, come join us. Besides the practical aspects, we have a stellar line-up of speakers to learn from and discuss with: kuffmode.github.io/OHBM2026Neur...
What happens when 18 teams of expert neuroscientists analyze the exact same neurophysiology dataset? You might expect convergence, but that is not what we found. Very grateful for the opportunity to write with Gaëlle Chapuis about one of my favorite projects since I started working in science! 1/n
The Transmitter @thetransmitter.bsky.social · 4mo agoA hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
Come join the lab @maynoothuniversity.ie and work with me and stellar collaborators @seanfw.bsky.social and @redmondoconnell.bsky.social! Exciting project at the intersection of multi-task RNNs, compositional cognition and human decision neuroscience. Details and how to apply at shorturl.at/FsTQ0
Neuroscience Ireland@neuroscienceirl.bsky.social · 4mo ago✅Funded PhD studentship in computational modelling of supra-modal evidence accumulation/decision-making! ⏰ Closing date: 1st July 2026! ➡️ More information: shorturl.at/FsTQ0 @redmondoconnell.bsky.social @seanfw.bsky.social @maynoothuniversity.ie @tcdpsychology.bsky.social
Introducing the International Brain Lab AI Agent: a tool to help researchers analyze neural activity from across the mouse brain, using AI coding agents. Please try it! We would love your feedback. github.com/int-brain-la...
🚨 Registration is NOW OPEN for the Pre-FENS Brainhack (July 5, Barcelona)! 🧠💻 100 spots only — first come, first served ⏳ No FENS registration needed 🙌 Sign up here 👉 pre-fens-brainhack.github.io/brainhack2026/
International Brain Laboratory@intlbrainlab.bsky.social · 6mo ago🧠💻 Join the Brainhack satellite at #FENS2026 (July 5)! ✨ Open to all - no FENS registration required 📆 Registration opens April 9 ⚠️ Limited to 100 spots (first come, first served) Learn more: pre-fens-brainhack.github.io/brainhack2026/ #Brainhack #OpenScience #Neuroscience
For all the esteemed scholars out there who prefer gaining knowledge the correct way, here’s a summary of our upcoming opinion piece, delivered to you by Jesus himself. But seriously, science communication is about to get a lot worse and better at the same time.
Love the website and the series. Super happy to be part of it! 😃
The Transmitter @thetransmitter.bsky.social · 5mo agoIn this month’s “Liftoff,” @laurenkreeger.bsky.social says she’ll encourage lab members to share “away from the bench” slides at lab meetings, and @mattiachini.bsky.social talks about his love for outdoorsy lab retreats. #neuroskyence By @franciscorr25.bsky.social bit.ly/42pdL0E
⏳ Two weeks left to send us your Satellite Workshop proposals for the #BernsteinConference 2026! 🗓️ Deadline: April 29, 15:00 CEST More info 👉 bit.ly/40HybkI #BernsteinNetwork #CompNeuro
🧠 Registration is OPEN for Brainhack @ #FENS2026 (July 5) Explore how different analysis choices shape results Open to all — no FENS reg needed ⚠️ 100 spots, first come Register: forms.gle/c9xDSSuFeRmY... #Brainhack #OpenScience #Neuroscience
✨Excited to share that our new preprint, "Mapping developmental patterns of intrinsic timescale", is now available on bioRxiv!! 📚 doi.org/10.64898/202...
doi.org
🚨 Registration is NOW OPEN for the Pre-FENS Brainhack (July 5, Barcelona)! 🧠💻 100 spots only — first come, first served ⏳ No FENS registration needed 🙌 Sign up here 👉 pre-fens-brainhack.github.io/brainhack2026/
International Brain Laboratory@intlbrainlab.bsky.social · 6mo ago🧠💻 Join the Brainhack satellite at #FENS2026 (July 5)! ✨ Open to all - no FENS registration required 📆 Registration opens April 9 ⚠️ Limited to 100 spots (first come, first served) Learn more: pre-fens-brainhack.github.io/brainhack2026/ #Brainhack #OpenScience #Neuroscience
Such a beautiful flyer 😍 Join us in Barcelona!
Andrea Navas-Olive@acnavasolive.bsky.social · 6mo agoIf you are interested in systems neuroscience, learning about data analysis, or understanding how the conceptualization of analyses can influence results, join us for the Brainhack satellite event at #FENS2026! More info at: pre-fens-brainhack.github.io/brainhack2026/
Final stop for Con2Phys: Barcelona! After two amazing editions at COSYNE and Bernstein, we’re doing one last collaborative team-based hackathon. Open to all, but spots are limited. Registration opens on April 9, put it in your calendar! 👇😱 #Brainhack #OpenScience #Neuroscience #Fens2026
International Brain Laboratory@intlbrainlab.bsky.social · 6mo ago🧠💻 Join the Brainhack satellite at #FENS2026 (July 5)! ✨ Open to all - no FENS registration required 📆 Registration opens April 9 ⚠️ Limited to 100 spots (first come, first served) Learn more: pre-fens-brainhack.github.io/brainhack2026/ #Brainhack #OpenScience #Neuroscience
Attending #FENS2026? Don't miss this satellite event! 👇 Registration opens tomorrow!
Mattia Chini@mattiachini.bsky.social · 6mo agoFinal stop for Con2Phys: Barcelona! After two amazing editions at COSYNE and Bernstein, we’re doing one last collaborative team-based hackathon. Open to all, but spots are limited. Registration opens on April 9, put it in your calendar! 👇😱 #Brainhack #OpenScience #Neuroscience #Fens2026
Final stop for Con2Phys: Barcelona! After two amazing editions at COSYNE and Bernstein, we’re doing one last collaborative team-based hackathon. Open to all, but spots are limited. Registration opens on April 9, put it in your calendar! 👇😱 #Brainhack #OpenScience #Neuroscience #Fens2026
International Brain Laboratory@intlbrainlab.bsky.social · 6mo ago🧠💻 Join the Brainhack satellite at #FENS2026 (July 5)! ✨ Open to all - no FENS registration required 📆 Registration opens April 9 ⚠️ Limited to 100 spots (first come, first served) Learn more: pre-fens-brainhack.github.io/brainhack2026/ #Brainhack #OpenScience #Neuroscience
Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr
G'day connection makers. On **April 16th**, we're hosting Georg Northoff telling us about intrinsic timescales. If it sounds interesting, here's the link to register: cam-ac-uk.zoom.us/meeting/regi...
Forgot to properly tag the person who did all the job 😢 @irinapochinok.bsky.social
Mattia Chini@mattiachini.bsky.social · 6mo agoNew paper out in PLOS Computational Biology! We introduce iSTTC, a robust method to estimate intrinsic neural timescales from single-unit recordings. Congrats to Irina Pochinok for leading the project! Package: github.com/iinnpp/isttc Paper: journals.plos.org/ploscompbiol...
New paper out in PLOS Computational Biology! We introduce iSTTC, a robust method to estimate intrinsic neural timescales from single-unit recordings. Congrats to Irina Pochinok for leading the project! Package: github.com/iinnpp/isttc Paper: journals.plos.org/ploscompbiol...
GitHub - iinnpp/isttc: iSTTC: intrinsic neural timescales estimation
iSTTC: intrinsic neural timescales estimation. Contribute to iinnpp/isttc development by creating an account on GitHub.
github.com
New preprint from the lab on synapse development in the nascent neocortical hierarchy! Using mice that label MAGUK proteins developed by Seth Grant we find key differences in the laminar maturation of association and sensory motor cortices, including delayed, cortex-wide maturation of L1 synapses.
I’m very excited to announce that a part of my PhD thesis project is now a preprint! In this paper, we show how spontaneous activity prior to visual experience shapes neural circuits in the retina. (1/11)
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 8mo agoRetinal waves shape starburst amacrine cell dendrite development through a direction-selective dendritic computation https://www.biorxiv.org/content/10.64898/2026.02.02.701812v1
Paper out in @brainbehavimm.bsky.social! Big congrats to Anne who did all the hard work for this one 👏🎉 www.sciencedirect.com/science/arti...
Early rebalancing of neuroinflammatory cascades lastingly rescues prefrontal deficits in a 22q11.2ds model
Cognitive deficits, a characteristic feature of neuropsychiatric disorders, reflect perturbed activity in neuronal networks. Increasing evidence has l…
sciencedirect.com
Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻 Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems. See below for + details and retweet 🙏
Main postdoc study out! We can redefine prefrontal cortex regions with single-unit activity! Grateful to @carlenlab.bsky.social and @weltgeischt.bsky.social who made this crazy project real. Thanks to all co-authors, collaborators, and reviewers. www.nature.com/articles/s41...
A prefrontal cortex map based on single-neuron activity - Nature Neuroscience
The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity...
nature.com