Finally out in @natneuro.nature.com! A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work! www.nature.com/articles/s41...

If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" https://link.springer.com/article/10.1038/s44318-026-00879-w […] [Original post on biologists.social]

New preprint: www.medrxiv.org/content/10.6... We built a mechanistic simulator of youth mental health: the Coupled Stochastic Dynamical System (CSDS) ...and tested whether its synthetic people behave like real ones. They do, more than we expected. 🧵

The Coupled Stochastic Dynamical System: A Generative Model for Simulating and Forecasting Youth Mental Health Trajectories

Mechanism-informed models that can simulate counterfactual mental-health trajectories remain scarce in digital phenotyping. Most existing approaches either predict outcomes from sensor-derived data wi...

medrxiv.org

𝗡𝗲𝘂𝗿𝗮𝗹 𝘁𝗿𝗮𝘃𝗲𝗹𝗶𝗻𝗴 𝘄𝗮𝘃𝗲𝘀 𝗶𝗻 𝗰𝗼𝗿𝘁𝗲𝘅: 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗮𝗻𝗱 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗿𝗼𝗹𝗲𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻 A must read for systems neuroscience. #neuroskyence doi.org/10.1016/j.ne...

If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...

Climbing fibers encode the gradient of a loss function for the cerebellum

Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...

biorxiv.org

👀 The State of Motion: Demographic and representational consequences of motion-based exclusion in fMRI | bioRxiv www.biorxiv.org/content/10.6...

🚨 #preprint update: "High-amplitude oscillatory events coordinate large-scale cortical interactions during decision-making and attention allocation" @biorxiv-neursci.bsky.social including 3 novel (control) analyses 🧵 #neuroskyence #oscillation #MEG #cogpsyc www.biorxiv.org/content/10.1...

High-amplitude oscillatory events coordinate large-scale cortical interactions during decision-making and attention allocation

How do large-scale functional brain networks dynamically emerge to enable cognition? Correlated oscillations, a mechanism for inter-areal interactions, can be expressed as phase coherence or correlate...

biorxiv.org

My PhD student Liyuan Jiao has published her very first article in Topoi, a lovely piece describing some difficulties with manipulationist approaches to causation. Congrats Liyuan! Go check it out- link.springer.com/article/10.1...

Extending Causation Beyond Manipulation: Analogical Reasoning in Two Theories of Causation - Topoi

Analogical reasoning has played an important role in philosophical theory, including manipulationist approaches to causation. Manipulationism ties causal judgments to the idea that causes function as ...

link.springer.com

A multimodal interrogation of Broca's area in the pediatric and adult human brain | bioRxiv www.biorxiv.org/content/10.6...

'Brain rhythms of depression: A predictive processing perspective' by Andreas Strube @astrube.bsky.social & Diego Pizzagalli @diegopizzagalli.bsky.social www.cell.com/trends/neuro...

Final version: @bhartl.bsky.social, Leo Pio-Lopez, Chris Fields www.sciencedirect.com/science/arti... Remapping and navigation of an embedding space via error minimization: A fundamental organizational principle of cognition in natural and artificial systems

“Cerebral vasculature shapes the spatial patterning of brain metastases” Note: Systemic metabolic factors should be incorporated into the assessment of patient-level brain metastatic risk. Now available at: www.biorxiv.org/content/10.6...

1/ What can resting-state neuroimaging offer cognitive and translational neuroscience🧠? Turns out: a lot! 🧵 Long in the making, short in the reading: “Unlocking spontaneous cognition in the age of data science" is out now in @natrevneuro.nature.com rdcu.be/ftWBh

Unlocking spontaneous cognition in the age of data science

Nature Reviews Neuroscience - Spontaneous brain activity is experimentally unconstrained. Embracing this freedom unlocks rich opportunities beyond task-based and naturalistic paradigms, the...

rdcu.be

It's World Brain Day! We've all got one. Here's a fine example featured in Kaishi Hen, a 1772 anatomical atlas from the dawn of experimental medicine in Japan. More here: https://publicdomainreview.org/collection/kaishi-hen-an-18th-century-japanese-anatomical-atlas

Progressive neuronal network reorganisation in glioblastoma drives pathological activity in vitro https://www.biorxiv.org/content/10.64898/2026.07.16.738125v1

Whole-Brain, Region-Specific Astrocyte Reactivity and Morphological Remodeling After Diffuse Traumatic Brain Injury in A Gyrencephalic Ferret Model https://www.biorxiv.org/content/10.64898/2026.07.16.739056v1

General cognitive function and the brain's structural connectome | bioRxiv www.biorxiv.org/content/10.6...

"Here we used measurements in awake monkeys to show that the baseline-evoked relationships evident within these two different measures are unreliably coupled between them: baseline-evoked relationships of the pupil are not predictive of those in the LC, and vice versa."

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2w ago

Limitations of pupil diameter as a proxy for modes of locus coeruleus activity https://www.biorxiv.org/content/10.64898/2026.07.14.738598v1

I am *thrilled* to share this review in @currentbiology.bsky.social out today, by yours truly, @myoo.bsky.social, @michalk.bsky.social, Taro Toyoizumi, @tyrellturing.bsky.social, @taylorwwebb.bsky.social, & @hakwan.bsky.social www.sciencedirect.com/science/arti... 🧵👇

Looking to the brain to improve energy efficiency of AI

Modern artificial intelligence (AI) systems have achieved remarkable capabilities, but at an extraordinary energy cost. Training and running large-sca…

sciencedirect.com

A great new resource for future comparisons across model systems, species, and disease states, on @biorxivpreprint.bsky.social: a consensus atlas of human brain development, identifying cell type-specific maturation trajectories across the lifespan 🧪🧬🧠📈 www.biorxiv.org/content/10.6...

A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespan

Human neurodevelopment is a continuous process that begins prenatally and extends into postnatal life. Current transcriptomic datasets are limited, fragmented across analytical frameworks, precluding ...

biorxiv.org

Thanks to Kshipra Guranandan, my notebook on how to design efficient fMRI experiments (for activity, connectivity and pattern analysis) is now available in Python as a Jupyter notebook (as well as previous Matlab): github.com/RikHenson/fM...

GitHub - RikHenson/fMRIefficiency

Contribute to RikHenson/fMRIefficiency development by creating an account on GitHub.

github.com

And Chapter 3 of #ComplexityThoughts is out! If robustness cannot come from adding links without limit, which structures allow living systems to withstand perturbations? Read it here 👉 manlius.substack.com/p/decoding-the-architecture-of-living-e8f 🧵 1/

Decoding the “Architecture” of Living Systems: Chapter 3

DALV-03: loops, the minimal units of redundancy, control, and closure

manlius.substack.com

Manlio De Domenico@manlius.bsky.social · last mo.

Chapter 2 of this #ComplexityThoughts series is out. If living systems have “architecture” w/o an architect: where is this architecture “stored”? Read 👉 manlius.substack.com/p/decoding-t... Feat. @ricardsole.bsky.social @wiringthebrain.bsky.social @hectorzenil.bsky.social 🧵 1/

Self-organisation on the web browser 🧫🦠

ipsquiggle@ipsquiggle.bsky.social · 2w ago

If you like playing with fluid sims, game-of-life type shenanigans, etc... then hold on to your socks. aphid91.github.io/Fluoddity-Co...

New protocol paper (https://doi.org/10.37349/en.2026.1006138) describing Phases 4-5 of the Cam-CAN study of healthy ageing, led by Ina Demetriou Includes MRI and MEG data up to 14 years after baseline. Data available soon on https://cam-can.mrc-cbu.cam.ac.uk/dataset/

New paper 🧵 What if the "landscape" that guides cell differentiation isn't fixed, but is sculpted, in real time, by the very cells moving through it? We call this a 'sandscape' : grains of sand that carve dunes as they move, while the dunes' shape simultaneously steers where the grains go next.

Presentation of some topics of "The Brain, In Theory" and discussion on the Neuroscience & Philosophy Salon www.youtube.com/watch?v=XV6k...

Romain Brette discusses brains and computations

YouTube video by Neuroscience & Philosophy Salon

youtube.com

Is the brain a computer solved in 4 posts so that we never have to talk about this again (please please please). 1. It's not the same physically as a computer - it's made of meat. Hopefully this one at least is uncontroversial.

I went to ICIS in Panama last week, and the long trip back gave me time to think about how our field is doing and where it's heading. My general take is: there's not enough theoretical and methodological work in our field - but there's also reasons to be hopeful. A thread 🧵

New Preprint! We gave neural networks infant-like curiosity and let them free to explore. They grew brain-like architecture, followed human synaptic development, and even started to display compositional thought. So we think curiosity doesn't just come from a complex mind... it helps us build one 👇

Curiosity shapes brain-like architectures and functions

How does complex cognition emerge from simpler underlying processes? We show that two components are sufficient: infant-like curiosity and brain-like biophysical constraints jointly drive the emergenc...

biorxiv.org

Function is not tied to specific brain structures or time scales. The brain is not just a set of parts that each “do their own job”. Instead, networks are multifunctional and active across different speeds simultaneously. doi.org/10.1073/pnas... #neuroscience

Shared spatial and temporal principles govern connectome dynamics across timescales | PNAS

While the brain processes information at various speeds, little is known about how the functional connectome can concurrently support multiple spee...

doi.org