Calling all computational neuroscientists! Our department is recruiting two new lecturers/associate profs. Application deadline 10th July. tinyurl.com/4wnzvjc2 #sciencejobs @uclnpp.bsky.social

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

tinyurl.com

AI is about to transform how scientific research happens, and neuroscience is no exception. What the future looks like is up to us. I don’t have the answers; here are some thoughts from working on the IBL AI agent. Aiming to start a discussion.

Kenneth Harris@kenneth-harris.bsky.social · 3mo ago

Introducing the International Brain Lab AI Agent: a tool to help researchers analyze neural activity from across the mouse brain, using AI coding agents. Please try it! We would love your feedback. github.com/int-brain-la...

Introducing the International Brain Lab AI Agent: a tool to help researchers analyze neural activity from across the mouse brain, using AI coding agents. Please try it! We would love your feedback. github.com/int-brain-la...

New method for identifying the fine transcriptomic types of thousands of neurons recorded in vivo!

How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social

To make the best use of LLMs in research, turn your scientific question into a space of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate, writes @kenneth-harris.bsky.social. www.thetransmitter.org/neuroscienti...

How to collaborate with AI

To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.

thetransmitter.org

New preprint, on a very different topic: a mathematical theory of evolution for self-designing AI. AI is increasingly designed by AI. What systems might emerge after generations of self-designing AIs competing for computing resources? ↓ arxiv.org/abs/2604.05142

A mathematical theory of evolution for self-designing AIs

As artificial intelligence systems (AIs) become increasingly produced by recursive self-improvement, a form of evolution may emerge, with the traits of AI systems shaped by the success of earlier AIs ...

arxiv.org

How do the basal ganglia turn what you see into what you do? New preprint w/ @kenneth-harris.bsky.social, @flickerfusion.bsky.social & @carandinilab.net: we recorded across striatum, GPe & SNr in a Go/NoGo task. Striatum encodes which stimulus, GPe & SNr encode action. 🧵 biorxiv.org/content/10.6...

Sequences are everywhere! In every brain region. And are written in stone. Invariant Activity Sequences Across the Mouse Brain. Out today, by Célian Bimbard, with @kenneth-harris.bsky.social. Based on data by Célian and by @intlbrainlab.bsky.social. www.biorxiv.org/content/10.6...

Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here: www.ucl.ac.uk/cortexlab/po...

1. New preprint resolving a conundrum in systems neuroscience with an AI scientist, and humans Reilly Tilbury, Dabin Kwon, @haydari.bsky.social, @jacobmratliff.bsky.social, @bio-emergent.bsky.social, @carandinilab.net, @kevinjmiller.bsky.social, @neurokim.bsky.social www.biorxiv.org/content/10.1...

Characterizing neuronal population geometry with AI equation discovery

The visual cortex contains millions of neurons, whose combined activity forms a population code representing visual stimuli. There is, however, a discrepancy between our understanding of this code at ...

biorxiv.org

Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

A new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...