We are excited to announce a tenure-track position in Computational Biophysics and Biochemistry, exploring the intricate molecular and cellular processes and the complex interactions of their macromolecular components! apply.interfolio.com/193444

Check out our new perspective on a set of exciting studies tackling nuclear envelope fusion — one of the most enigmatic membrane fusion events in the cell! www.cell.com/molecular-ce... #CellBiology #NuclearEnvelope #MembraneFusion www.cell.com/molecular-ce...

To fuse, or not to fuse: Closing in on the nuclear envelope fusion machinery

Nuclear pore complex assembly is an intricate process occurring in the double bilayer of the nuclear envelope. In this issue of Molecular Cell, Fischer et al. Maslennikova et al. and Wang et al. integ...

cell.com

Congratulations to the 12 MB&B-affiliated students recognized in this year's NSF Graduate Research Fellowship Program — one of the nation's top honors for emerging STEM researchers — including 4 fellows and 8 honorable mentions! View the full list: bit.ly/4dWB7kT

MB&B is excited to announce that Christian Schlieker (@schliekerlab.bsky.social) will serve as MB&B’s next chair! A member of the department since 2009 and current Director of Undergraduate Studies, he will begin a three-year term on July 1, succeeding Ronald Breaker.

Last week, MB&B hosted Dr. Ryan Feathers (Princeton) for a hands-on workshop on AI for cryo-EM—showcasing cryoDRGN to reveal molecular heterogeneity in challenging datasets. Read more here: bit.ly/3QoEOqq #CryoEM #StructuralBiology @ryanfeathers.bsky.social

Thomas A. Steitz Lecture Series by @yalembb.bsky.social Dr. Rachel Green, “ZAK activation on the colliding ribosome”, hosted by Dr. Yong Xiong Monday, April 20 | 4:00 PM 📍O.C. Marsh Lecture Hall, Yale Science Building Open to Yale and affiliated institutions. Details in the flyer below

In a paper recently published in @actacrystd.iucr.org, MB&B's Jimin Wang presents two methods for detecting hydrogen atoms in high-resolution cryo-EM — visualizing what was once invisible. 🔬 Check out the article on our website: bit.ly/47Rra57 #CryoEM #StructuralBiology

Congratulations to Raymond Adkins, postdoc in the Howard Lab, on being selected as a 2026 @rescorp.org Fellow! The RCSA Fellows initiative supports outstanding early-career scientists as they prepare to launch independent academic careers. bit.ly/4cfoako

2026 RCSA Fellows

Research Corporation for Science Advancement has selected a new cohort of 12 outstanding postdoctoral scholars in the third year of the RCSA Fellows initiative.

bit.ly

Congrats to MB&B's own Julien Berro, PhD, named a @biohub.org Investigator! 🎉 His work will focus on programmable mechano-transducers for precision diagnostics & therapeutics.

Biohub@biohub.org · 6mo ago

We’re thrilled to welcome 11 new investigators—visionary scientists from @columbiauniversity.bsky.social, @rockefeller.edu & Yale University who will pursue ambitious, high-impact research and contribute to our Immune Cell Reprogramming work. Learn more ➡️ biohub.org/news/investi...

Yale MB&B's Karla Neugebauer and Guillermina Kubaczka have been featured in a new @natmethods.nature.com piece 🌍🔬 The article spotlights researchers bridging the molecular and planetary scales to address global health challenges. @karlaneugebauer.bsky.social www.nature.com/articles/s41...

Cell biology’s fantastic voyage to Planet Earth - Nature Methods

A nascent group of researchers sees planetary health as an urgent reason to bridge the molecular and planetary scales. This is shaping their strategies, methods, collaborations and outlook about their...

nature.com

Congratulations to Susan Baserga, William H. Fleming Professor of Molecular Biophysics and Biochemistry, on being named a Fellow of the AAAS! Learn more about her recognition and the other Yale affiliates named to the latest class of @aaas.org Fellows:

MB&B's Dr. Christian Schlieker is featured in the Spring 2026 issue of Dystonia Dialogue from the Dystonia Medical Research Foundation. His lab has been dissecting the genetic networks underlying dystonia, a severe movement disorder. Check out the article for a look at where his work is heading.

Dystonia Dialogue • Spring 2026 • Page 4

mydigitalpublication.com

From a Wisconsin dairy farm to Sterling Professor & HHMI Investigator at Yale 🧬 MB&B Chair Ron Breaker's discovery of riboswitches is now connecting to human health, with new findings on guanidine-sensing RNAs and spinocerebellar ataxia. Read more here: mbb.yale.edu/news/feature...

Read Lily Kabeche's interview in the Journal of Cell Science about her career path and mentoring philosophy: journals.biologists.com/jcs/article/...

Congrats to MB&B senior Isabel Rancu on her Marshall Scholarship! She'll pursue a Master of Research in bioinformatics and theoretical systems biology at Imperial College and a Master of Science in applied infectious disease epidemiology at University College London. More here: tinyurl.com/2p9mdazj.

We are excited to announce a tenure-track or tenured faculty position in Computational Biophysics and Biochemistry, exploring the intricate molecular and cellular processes and the complex interactions of their macromolecular components! apply.interfolio.com/177120

🧠Pain sensors need to switch on fast—and off just as quickly. In our new tour de force Nat Comms paper - led by the first Paulsen lab grad student - we show that calmodulin plays a key role in shutting down the TRPA1 pain receptor - a finding that could guide new pain therapies. 📰 rdcu.be/eJcMK

Calmodulin binding is required for calcium mediated TRPA1 desensitization

Nature Communications - For pain signaling to be useful, sensory receptors must rapidly detect noxious stimuli and efficiently turn off once the threat has passed. Here, the authors uncover a...

rdcu.be

Thank you to everyone who attended this year’s retreat at the Heritage Hotel. A special thank you to retreat coordinators Enrique De La Cruz, Rachel Agosto, and Liz Vellali!

Malvankar lab publishes pioneer research delving into the quantum mechanics underlying bacterial respiration mbb.yale.edu/news/malvank...

Ailong Ke Leads Study Revealing Hidden RNA‑Editing Activity in CRISPR‑Cas9 www.cell.com/cell/fulltex...

Conversion of IscB and Cas9 into RNA-guided RNA editors

An engineered RNA-guided editing platform for efficient gene knockdown and sequence correction at the mRNA level.

cell.com

Heffler and @LammerdingLab.bsky.social discuss recent studies from the @schliekerlab.bsky.social (doi.org/10.1083/jcb....) and @hennelab.bsky.social (doi.org/10.1016/j.ce...) that identify two proteins serving as crucial mechanical elements in the endoplasmic reticulum. rupress.org/jcb/article/...

Congratulations to Enrique M. De La Cruz for his election as President of the Biophysics Society! mbb.yale.edu/news/congrat...

🔬 Join us LIVE on Zoom this Wednesday, June 11, at 4 PM ET! We’re excited to co-host the RNA Collaborative Seminar Series featuring 🎙️ Dr. @siggyn5.bsky.social (Yale RNA Center) 🎙️ Dr. Alex Wesselhoeft (HMS Initiative for RNA Medicine) Registration 👉 lnkd.in/e-9Huhzd

🧬 June RNA Club at Yale 📅 Tuesday, June 10th, 2025 📍 Location: Bass Center 305, Yale Science Building (Science Hill) This month’s speakers: 🔹 Dr. Chengtao Xu (Ke Lab) 🔹 Dr. Jyotsna Kumar (Garg Lab) 📣 Come for the science—stay for the conversations!

We’ve pioneered a disease-agnostic screening platform for aberrant biomolecular condensates—cellular structures linked to incurable neurological diseases. We screened genes and FDA-approved drugs that modulate disease-relevant nuclear condensates: www.biorxiv.org/cgi/content/...

Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305!

we are beyond proud that our @yalembb.bsky.social @schliekerlab.bsky.social undergraduate researcher Sophia graduated as the sole @Yale Colleague '25 graduate with an exceptional distinction in the major! Congrats Sophia for this richly deserved honor!

Join our department as a Lecturer! Apply here: apply.interfolio.com/163609.

A useful tool and a great thing to do... 5calls.org/issue/nih-ns...

Save NIH and NSF Research Funding ⭑ 5 Calls

On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …

5calls.org

📣 New work from MB&B graduate student Max Paul, published in PNAS, reveals how a conserved region of the RasGAP C2 domain enhances enzymatic activity via allosteric interaction with Ras. Structural & functional data suggest a key role in Ras regulation! 🧫🔬 mbb.yale.edu/news/mbb-gra...