📣 Register for #MCCS26 now! Join us on November 12 & 13 in Washington, DC for talks, networking, and an all-around great time! To be considered as a selected speaker, submit your abstract by August 21. More information here: event.fourwaves.com/4599d6d4-273...
Denise J. Cai, Ph.D.
@denisejcai.bsky.social
Prof. of Neuroscience @SinaiBrain · Investigating memory stability & flexibility · Advocate for open science · Mom of two littles · Amateur chef · she/her · denisecailab.com
Huge congrats to Cai Lab postdoc @destyniemedeiros.bsky.social for being named a @simonsfoundation.org Junior Fellow! 🎉 Destynie is a brilliant rising star 🌟 The rigor of her science and the leadership she has built in our community impress me again and again. So well earned. Congrats, Destynie! 🧠✨
Looking forward to this webinar! 🤓 Thank you to AFAR and MBRF for hosting it for World Brain Day! Register to watch it here: us02web.zoom.us/webinar/regi...
Less than 2 weeks until our brain health webinar with the American Federation for Aging Research, featuring Leah Acker, MD, PhD, Duke University, Denise Cai, PhD, Icahn School of Medicine at Mount Sinai & Amit Etkin, MD, PhD, Alto Neuroscience. Learn more & RSVP: us02web.zoom.us/.../reg.../W...
🤔 Why does prior stress make future stress hit harder? In new work led by @zachtpennington.bsky.social, the Cai Lab discovered a brain circuit that controls stress vulnerability, reshaping how the brain reacts to the next stressor. I'll be speaking about at @fens.org. Come check it out!
🎉 Congratulations to @zachtpennington.bsky.social on receiving this year's Banting Discovery Award! I worked closely with Zach when he was a postdoc in my lab and I know he is incredibly deserving of this award. Read more about his award here: psych.ubc.ca/news/zachary...
Join our mailing list and never miss an update for #MCCS26! We'll send you no more than 6 emails per year. Join here: t.co/noAbGJgNHc
🌎 Check out the new GLOBE tool that uses protein tape recorders to measure single-cell activity on a brain-wide scale. Congratulations to Changyang and team on developing and sharing this platform. Let us know what you think! www.biorxiv.org/content/10.6...
Introducing GLOBE—a new technology for brain-wide, single-cell recording of cellular activity in vivo. GLOBE can continuously record from nearly a quarter million individual neurons simultaneously across a mouse brain. Preprint out on bioRxiv: doi.org/10.64898/202... 🧵(1/6)
Representational drift - the change in cells' responses to the same stimulus over time - may be a feature rather than a bug. Thank you to @dianakwon.bsky.social for giving me a chance to talk about this fascinating topic. 🤯 The brain never ceases to amaze!
My latest feature for @nature.com is about "representational drift," a concept that's turned some long-standing ideas of how the brain works on its head. “When people talk about this phenomenon, it’s exciting because it’s just so full of possibilities." - Andrew Fink
I had a fantastic time at #OptoGRC2026! Congratulations to Cai Lab member @austinbaggetta.bsky.social for winning best poster 🎉 Shout out to @tristanshuman.bsky.social & @lindsayschwarz.bsky.social for taking on the role of Vice Chairs for the next meeting 🤓
Join us in Paris this summer for our #Miniscope Workshop 🔬 We'll teach you everything you need to know about miniscopes and have a blast while we're at it! Applications close on May 22, so don't wait 👇
Applications open for 2026 Paris Miniscope Workshop! July 1-3, hosted at ESPCI. Apply here: forms.gle/4CWh7MeMchLS...
So incredibly proud to celebrate these two remarkable researchers I've had the privilege to work with! @joezaki.bsky.social and Rimi are truly deserving recipients of the #LeonLevyScholars recognition for 2026. They continue to make invaluable contributions to the field!
Reminder: Your impact is bigger than just papers ✨ At this year's Slaydies retreat, we gave each other personalized awards, holistically honoring the way we show up for each other in the neuroscience field and beyond. I'm so grateful for this community 💜
We held another incredible Memory Hub meeting at @sinaibrain.bsky.social last week, featuring @suthanalab.bsky.social and @antferrui.bsky.social, who presented their creative topic "One Rhythm, Two Species? Rethinking the functional role(s) of hippocampal theta" 🧠 🤓 It was great to see everyone!
Last week, I spent an incredible evening full of music at @onemindorg.bsky.social's 'Apollo & Psyche' celebration 🎶 Thank you for highlighting the healing power of music, One Mind. Music is such a valuable tool for mental health! Read about the event here: onemind.org/news/one-min...
🤓 Really excited to host this panel at COSYNE! Our incredible speakers Bing, Kenji, Kim & Saskia are sure to share insightful advice on making an impact in their career and community at every stage of their careers 🧑🔬 🧠
As a past Next Generation Leader, I can definitively say the program helped shape how I approach my science. Collaboration is key to making an impact, and so is backing innovation with values-driven research. I highly recommend applying for this program 🧠
Applications for our Next Generation Leaders program are open! For 3 years, accepted early career scientists will join a supportive network and contribute to our research initiatives. Apply by Mar. 31: https://bit.ly/3OjzdRa 📸 Photo by NGL Alum @bjmarlin.bsky.social
How does neuronal gene expression evolve over time in response to experience? CytoTape will help us find out - a major milestone for neuroscience, providing new ways to study memory & aging 🧠 Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
#ACNP2026 was the perfect way to start the year with some of my favorite scientists! I had a great time talking science (sometimes with my toes in the sand!) and strategizing ways to support the younger generation of scientists at the @onemindorg.bsky.social luncheon 🔬
What happens when a neuroscientist realizes trauma rewired their own brain? ❤️🩹 I’ll be sharing that very personal story - the intersection of my research, insights it's brought me & the healing journey I've embarked on - LIVE & LIVESTREAMING on 1/26! Tickets 👇 www.storycollider.org/tickets/2026...
On Jan 26, Do Not Miss UNSPOKEN, an @storycollider.bsky.social event @caveatnyc.bsky.social! JOIN Diana Li & @paulacroxson.bsky.social when they host @denisejcai.bsky.social & 4 other story tellers for an unforgettable evening of deeply personal stories.🎟️🎟️ 👉 www.storycollider.org/tickets/2026...
🤓 So grateful to learn from powerhouses like Erin and @huda-akil.bsky.social during our Stories of WiN panel. We spoke about defining your legacy in science & beyond and a clear theme emerged: do science & lead according to your values. Listen here: www.storiesofwin.org/profiles/202...
The Cai & Shuman Labs threw an EPIC White Elephant party! So much holiday cheer packed into one room. We did not have a partridge in a pear tree, but we did have: 👥 25 members laughing 🥔 6 chip-bags-a-gifting 🪴 5 plants-afloating 🦫...and a capybara in a knit hat!
Wow, such an insightful and substantive open floor discussion at last night's Memory Hub meeting! 🤓 Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
Thank you to everyone who came out to the Cai-Tye Collective party at #SfN25 🎉 You all brought your amazing energy from the poster floor to the dance floor. I'm still smiling from what a great time it was!
🎉 We had a great time at #MCCS25 and can't wait to see everyone at next year's meeting! Don't forget to join our mailing list for information about #MCCS26 in the coming year: bit.ly/4r1YApk
Thank you to everyone who came out to #MCCS25 last week! It was great to hear all the exciting research happening in the field of molecular and cellular cognition 🧠 🤓 A special thank you to all our incredible speakers for sharing their work! Don't forget to join our mailing list: bit.ly/4r1YApk
I'll be at Zoé and Zach's posters today, giving out VIP access bracelets for the Cai-Tye Collective event tonight! If you're at #SfN25, come check out Zoé and Zach's work and snag a bracelet before we run out!
Are you at #SfN25 and want VIP access to the Cai-Tye Collective event on Nov 17? Come by my lab members' posters for a bracelet! Hailey Rosenblum: Nov 15, 1-5pm PSTR040.05/BB6 Zoé Christenson Wick: Nov 17, 8am-12pm PSTR192.01/RR13 Zach Pennington: Nov 17, 1-5pm PSTR234.05/CC7
Reunion with past and present Cai lab & Shuman lab members (and collaborators). Spending time with you guys is easily the best part of my job. @tristanshuman.bsky.social @sinaibrain.bsky.social @sfn.org
Congrats @sjo09.bsky.social! Your trailblazing engram discoveries are unforgettable. So happy that the Peter Seeburg Integrative Neuroscience Prize is honoring YOUR Era's tour @sfn.org.