Anna Molofsky Lab
@annamolofskylab.bsky.social
brain immune communication throughout the lifespan and in neuropsychiatric diseases
IFN-brite: A new interferon reporter from our lab designed by Dr. Sarah Anderson is bright and pan cellular
Waggoner Lab@labwaggoner.bsky.social · 7mo ago@biorxivpreprint.bsky.social A genetically encoded reporter reveals interferon responses in multiple cell lineages www.biorxiv.org/content/10.6... @annamolofskylab.bsky.social
I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness. www.kpbs.org/podcasts/kpb...
Nobel laureate on how Trump's cuts are hurting science
Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...
kpbs.org
I am saddened by this news. Atul was a vibrant colleague and tireless proponent of using data to unravel the complexity of disease.
New pre-print from our lab here: www.biorxiv.org/content/10.1...
Detection of astrocyte epigenetic memory in in vitro systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples
We recently described astrocyte pro-inflammatory epigenetic memory based on multiple complementary in vivo and in vitro studies, and the analysis of multiple sclerosis samples. Based on bioinformatic ...
biorxiv.org
Have you registered yet for #ReThinkNeuroimmunology in October? Speakers include @aleksdelab.bsky.social @labschaefer.bsky.social @annamolofskylab.bsky.social @itchdoctor.bsky.social @becherlab.bsky.social @gocastelobranco.bsky.social @miriammerad.bsky.social @kuchroolab.bsky.social & more
RTN Conference@rtnconference.bsky.social · last yr.#ReThinkNeuroimmunology 3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology. Organized by @quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua Registrations 🔗 genelayinstitute.org/rtn/
We're now appreciating how the immune and nervous systems communicate across body & brain, and there's still more to explore! Had a fun time co-writing this with some amazing immunologists and neuroscientists @nickmroz.bsky.social @arimolofskylab.bsky.social @annamolofskylab.bsky.social 😎🧠
Cross-regulation between the nervous system and type 2 immunity
The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters, suggesting previously unidentified therapeutic avenues.
science.org
Review @sciimmunology.bsky.social @arimolofskylab.bsky.social @annamolofskylab.bsky.social @nickmroz.bsky.social @phagocyticpai.bsky.social The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters www.science.org/doi/10.1126/...
This month in #Science #Immunology: @nickmroz.bsky.social, @phagocyticpai.bsky.social, @annamolofskylab.bsky.social, & @arimolofskylab.bsky.social pen an insightful & timely Review on crosstalk between the #nervous system & #type2 immunity! #WeekendRead #neuroimmunology #allergy #Alzheimers #itch
Cross-regulation between the nervous system and type 2 immunity
The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters, suggesting previously unidentified therapeutic avenues.
science.org
#ReThinkNeuroimmunology 3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology. Organized by @quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua Registrations 🔗 genelayinstitute.org/rtn/
RTN Conference@rtnconference.bsky.social · last yr..@washumedicine.bsky.social @weizmanninstitute.bsky.social @genelayinstitute.bsky.social @massgenbrigham.bsky.social
This was the last @hhmi.org conference Lilly and Yuh-Nung Jan attended as investigators. They're becoming HHMI emeritus but still run a thriving NIH-funded lab. From cloning the first potassium ion channel (Shaker) to decoding neuronal development, the Jans have made a huge impact.
Thousands of federal health workers woke up on April 1 to find they had been fired or laid off. Scientists and civil servants at the FDA, CDC, and NIH were let go as part of Robert F. Kennedy Jr.'s pledge to cut jobs at the country’s most important disease-fighting agencies.
The Department Of Health And Human Services Cuts 10,000 Jobs
The cuts hit multiple agencies, affecting work on HIV, gun violence prevention, vaccines, minority health research, and more.
sciencefriday.com
www.wired.com/story/doctor... “To get rid of 11 of our senior PIs … we’re hoping that’s a mistake, because we can’t figure out why they would want to do that,”
Doctor Behind Award-Winning Parkinson’s Research Among Scientists Purged From NIH
Leading scientists at the National Institutes of Health, the US’s leading medical research agency, were swept up Tuesday in the Trump administration’s latest firing blitz.
wired.com
Removing the top leadership at NIAID, NIH and other health agencies, including the CDC and FDA, will damage America’s position as a leader in groundbreaking research in disease prevention and treatment. That puts us all at risk. Read our statement: asm.org/Press-Releas...
ASM Statement on Removal of NIH & NIAID Leadership
Removing the top leadership at NIAID, NIH and other health agencies including CDC and FDA will damage America’s position as a leader in groundbreaking research in disease prevention and treatment.
asm.org
Go John and Boaz! new gene therapy for Dravet
allen institute@alleninstitute.org · last yr.Good news! Thanks to brain research, there's new hope for a future cure for Dravet syndrome - a devastating condition impacting children and their families. We spoke with @fox13seattle.bsky.social's @mireyag.bsky.social about the incredible success of the gene therapy in mice and what's next. 🧠📈
Dysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner @cellcellpress.bsky.social @jonykipnis.bsky.social www.cell.com/cell/fulltex...
We have no memories for events from our earliest childhood years (aka infantile amnesia). Is it because we can't form them or can't keep them? Our Perspective on exciting new work from @tristansyates.bsky.social and colleagues. Babies form fleeting memories | Science www.science.org/doi/10.1126/...
Babies form fleeting memories
The human hippocampus constructs short-lived memories from around 1 year of age
science.org
“This review belongs in the canon of papers that inspire deep theory work,” writes Stephanie Palmer about a groundbreaking review by her mentor—Allison Doupe—and Patricia Kuhl that helped the field define the neural and evolutionary dynamics of speech. #neuroskyence
Stephanie Palmer on human speech, birdsong and a mentor
A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl shaped the field of neural and evolutionary dynamics of speech.
thetransmitter.org
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH
This is one of the best features I have seen on blue sky yet- a custom feed of papers from people you follow. I had to un-follow the various biorxiv channels, as it was dominant, but now I am seeing lots of cool papers from people I follow. Great work on this feed, @paper-feed.bsky.social team!
Paper Skygest Team@paper-feed.bsky.social · last yr.Welcome to your personalized Paper Skygest, a curated feed showing posts from your network. 📌 To pin this feed, select the pin icon at the top right of the feed. When you pin it, you'll see it up above here! ➡️ Follow this account for Skygest updates!
Where does TrumpElon think innovation for all their favorite biotech corporations comes from? PCR only exists because somebody was looking for bacteria in hot springs at Yellowstone. I’m just a private practice ophthalmologist who barely understands p values but even I know this shit is important.
Rachael Sirianni, PhD@docsirianni.bsky.social · last yr.This is my institution. These are the people I work with making these decisions. The situation is heartbreaking. Public medical schools have no other choice; there is no other source of funding, and everyone in academia is at extreme risk right now.
A recent study found that cervical cancer deaths in young women have plummeted since the introduction of the human papillomavirus vaccine.
As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine
HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.
buff.ly
Dendrite specific linking of memories over time - a cool extension of the work from @sjo09.bsky.social, @denisejcai.bsky.social, and others: www.nature.com/articles/s41... #neuroscience 🧪
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time - Nature Neuroscience
Sehgal et al. show that branch-specific dendritic plasticity mechanisms in the retrosplenial cortex link memories acquired close in time such that, unlike independent memories, linked memories are enc...
nature.com
Agree! An honor to receive the Bowes award together with @kampmann.bsky.social - a testament to the incredible collaborations at @ucsfhealth.bsky.social that make our science possible!
Martin Kampmann@kampmann.bsky.social · last yr.Honored and grateful to receive the 2025 Bowes Biomedical Investigator Award - along with my friend, colleague and collaborator @annamolofskylab.bsky.social 😊🎉🎉🎉 www.ucsf.edu/news/2025/02...
