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Ruth Montgomery

@rrmsky.bsky.social

Immunologist at Yale School of Medicine Associate Dean for Scientific Affairs @YaleMed Innate immunity ❤️

37 Posts1102 Follower249 Folgt
Admirable Women@admirablewomen.bsky.social · 2w ago

Chemist & X-ray crystallographer Rosalind Franklin's meticulous research was instrumental in uncovering DNA's molecular structure. Most famous for her role in the DNA double helix discovery, her work also revolutionized our understanding of viruses & coal. She was born #OTD in 1920. #WomenInSTEM 🧵

A classic, black-and-white studio portrait of a young Dr. Rosalind Franklin (1920–1958), the pioneering British chemist and X-ray crystallographer whose data was foundational to uncovering the double-helix structure of DNA. Captured from the chest up, Franklin sits in a three-quarter pose, her body angled slightly toward the left while her gaze directly meets the viewer. She possesses a calm, intelligent, and subtly enigmatic expression, with her dark hair neatly parted on the side and styled back away from her face. She wears a dark, long-sleeved button-down blouse with structured shoulders, a sharp collar, and fabric buttons down the front placket. The background is a soft, minimalist studio gradient of neutral grays that creates a gentle vignette effect, casting a soft light on the right side of her face. The composition is clean, formal, and balanced, evoking a mood of quiet determination, dignity, and brilliant intellectual poise characteristic of the early 20th-century scientific vanguard.
Yale University@yale.edu · 3mo ago

Can eating less help us age better? Research has long shown that cutting calories can improve lifespan in some species, but it’s not always practical or healthy for people. Now, a study from immunobiologist Vishwa Deep Dixit is exploring how we might get those same benefits without the risks.

Cutting Calories to Slow Aging--Without Compromising Health

Scientists found a potential target for achieving the healthy longevity that can come with calorie restriction, without the negative effects it can have on the

bit.ly

Amy C Fan (she/her)@amycfanphd.bsky.social · 3mo ago

Excited to announce our new study (w/ @maxkrummel.bsky.social) published today @nature.com: Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells. www.nature.com/articles/s41... #immunology #cellbiology @immunox.bsky.social

Submicrometre sampling of living cells by macrophages - Nature

Macrophages can sample antigens from living cells through a trogocytosis-like mechanism that routes ingested material away from degradation, a finding that delineates a previously unknown pathway...

nature.com

Ruth Montgomery@rrmsky.bsky.social · 4mo ago

We have age-associated macrophages in visceral fat making C3a and increasing inflammation. C'mon macrophages, we need your help here. Wonderful new paper from Dixit lab @yalemed.bsky.social #SenNet www.nature.com/articles/s43...

Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging - Nature Aging

Applying proteomics to longitudinal plasma samples from calorically restricted participants of the CALERIE trial, Mishra, Kim and colleagues link complement protein C3a to inflammaging. In aged mice, ...

nature.com

Ruth Montgomery@rrmsky.bsky.social · 4mo ago

Working together to advance understanding of human immunology. Well said Holden! @hipcproject.bsky.social

Human Immunome Project@immunome.bsky.social · 4mo ago

Stanford's HIMC has been at the frontier of systems immunology since Mark Davis founded it in 2007. But as HIMC Director Holden Maecker says, decoding the immunome is beyond the scope of any 1 lab. HIP is the global movement to change that. 🎥 youtu.be/yiFj3m4m3MU @stanfordimmunology.bsky.social

Prof Frank McDonough@fxmc1957.bsky.social · 4mo ago

FACT OF THE DAY. 26 March 1953. In a huge medical breakthrough, US medical researcher Dr Jonas Salk announced that he had created the first polio vaccine. Polio cases fell from 58,000 per year in 1952 to 6,000 by 1958. Salk’s vaccine was replaced by a new one developed by Albert Sabin in 1962.

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Simon Lab@vivianasimonlab.bsky.social · 6mo ago

Sharing on behalf of Dr. Florian Krammer for those interested - his podcast is great! Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases. Find it on Apple, Spotify, and Podigee: virological.podigee.io

viroLOGICAL

Florian Krammer is a virologist and vaccine developer. In his podcast viroLOGICAL he will talk about viruses on a weekly basis – from historical pandemics to current developments. A Podcastwerkstatt O...

virological.podigee.io

Denis Wirtz@deniswirtz.bsky.social · 6mo ago

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.

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Ruth Montgomery@rrmsky.bsky.social · 6mo ago

Glad to join today in teaching #CyTOF for Yale's Computational Proteomics course directed by Dr. Maria Rodriguez Martinez. Multidimensional single cell immune profiling for #HIPC takes a team including Dr. Adam Tanguay and Dr. Ashish Shelar.

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Ruth Montgomery@rrmsky.bsky.social · 8mo ago

Solo markers were interesting but combining gene SNPs and plasma metabolite data showed predictions for severe #COVID. That's why we study the whole #SystemsImmunology #BigScience #Teamwork

@precvaccines.bsky.social · 8mo ago

Our #IMPACC research in @pnas.org helps explain why people experience #Covid_19 so differently. @joanndarce.bsky.social @naama-kanarek.bsky.social @bostonchildrens.bsky.social @harvardmed.bsky.social @meduniwien.ac.at @yalemed.bsky.social @broadinstitute.org #NIAID pubmed.ncbi.nlm.nih.gov/41410771/

Admirable Women@admirablewomen.bsky.social · 8mo ago

Dr. Leila Denmark co-developed the pertussis (whooping cough) vaccine. World's oldest practicing pediatrician until she retired at age 103 (after 73 yrs). At the time of her death at age 114 & 60 days, she was the 5th-oldest validated living person in the world & 3rd-oldest in the US. #WomenInSTEM

A black-and-white photo shows Dr. Leila Denmark (center), an elderly woman with glasses, seated and smiling while looking at a baby who is laughing and facing her. Another younger woman is also seated to the right, laughing and placing her hand near the baby's midsection. The scene suggests a warm, inter-generational interaction, possibly in a clinical or home setting. Dr. Denmark was a pioneering pediatrician, known as the world's oldest practicing pediatrician upon her retirement at age 103.