You love #DendriticCells... how could you not? 😊 ⏰ Tomorrow is your last chance to register at the Early Bird rate! #DC2026 Join us this October in San Diego! dc2026sandiego.com 🙏 Please repost! 🔁 @maxkrummel.bsky.social @zunigalab.bsky.social
Max Krummel
@maxkrummel.bsky.social
Prof @ucsf/immunox, co-founder Solvingfor.org, Immunologist,Immunotherapy pioneer,believer in the power of curiosity,striving to make sense of complicated things, typically enthusiastic.
And then there is also this for traditional science communication!
One week left! ⏰ Early Bird Registration for #DC2026 ends on July 3. 🌍 Global dendritic cell community 🔬 Inspiring science & new discoveries ⭐️ Register now and save www.dc2026sandiego.com Come for the science. Stay for the community. @maxkrummel.bsky.social @zunigalab.bsky.social 🔁
My career bumpily took off with a discovery that proved world-changing, and from there, an eclectic, eccentric and fairly entertaining life took shape. The science, the life, the collaborations that make discovery happen—that’s what Immune Beyond is about.
Max Krummel | Substack
Click to read Max Krummel, a Substack publication.
theimmunebeyond.substack.com
Kuhn, @maxkrummel.bsky.social et al. demonstrate how local gene editing of cancer-associated fibroblasts alters their cell state and, subsequently, the cellular tumor microenvironment rupress.org/jem/article/... #TME #CAFs #TumorImmunology
In @jem.org, Kuhn, @maxkrummel.bsky.social et al. demonstrate how local gene editing of cancer-associated fibroblasts alters their cell state and, subsequently, the cellular tumor microenvironment rupress.org/jem/article/... #TME #CAFs #TumorImmunology
If dendritic cells are part of your science, #DC2026 should be part of your year! 🌍Global DC community in San Diego ✳️New biology & discoveries Abstracts & registration are OPEN www.dc2026sandiego.com ⭐️ Come for the science. Stay for the community. @maxkrummel.bsky.social @zunigalab.bsky.social 🔁
Registration is now open and an all-in roster of immunologists anchor the premiere Dendritic cell meeting. www.dc2026sandiego.com/invited-spea... Sunny (blue state) San Diego. Sessions devoted to honoring 15 year anniversary of Nobel prize (Steinman) and translational advances…what is not to like.?
How will our increasingly deep understanding of diverse immune archetypes in cancers guide our search for cures? This perspective describes a future in which we discover drugs based on transitions of tissue/immunobiology through intermediate states, to health. authors.elsevier.com/a/1llig5TA51...
Intravital imaging of pulmonary lymphatics in #inflammation and metastatic cancer. A new imaging approach developed by Simon Cleary (@simoncleary.bsky.social), Longhui Qiu, Mark Looney and colleagues: https://buff.ly/41msQjZ @maxkrummel.bsky.social
Tired of traditional peer review? Join the Discovery Stack Pilot study to help reshape scientific publishing! Contribute as a Reviewer or an Author. Learn more here: bit.ly/DiscoverySta... #ScienceRevolution #PeerImprovement #DiscoveryStackPilot #immunosky
Many tx studies (Mujal... Azizi…)failed to validate M1/M2 signatures in vivo. Many also suspected that calling cells bearing ‘prototypical M2’ genes ‘‘immunosuppressive’ was simplistic + incorrect. Nonetheless many (us too!) leaned on the simplification. Arja addresses the reality head on…thnx JEM
Rather than immune suppression, CD206+ TAMs recruit a tumor-reactive network of CD8 T cells, cDC1s, and NK cells doi.org/10.1084/jem.... @maxkrummel.bsky.social @jexpmed.bsky.social
Are so-called 'M2-like' CD206+ macrophages immunosuppressive? On the contrary, we find that they are critical for T cell mediated anti-tumor immunity. Arja Ray drove this study with help from Ken Hu, Kelly Kersten, Alexis Combes and others www.biorxiv.org/content/10.1...
Critical role of CD206+ macrophages in organizing anti-tumor immunity
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