Truly delighted to share this work from @isaacapaddy.bsky.social on probing a metabolic vulnerability in the Lyme disease agent Borrelia burgdorferi! onlinelibrary.wiley.com/doi/10.1002/...
A cofactor‐promiscuous <fc>HMGR</fc> from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis
The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopen...
onlinelibrary.wiley.com