The NIH just released a proposal that will apparently hide peer reviewers’ impact scores and percentiles from the research team, their institution, and NIH program officers. All the better to obscure how funding decisions will be made primarily via political review, I’m guessing.

Old lady in first author paper shocker! 🧪🧬🖥️ (ok but seriously I worked very hard on this and I am proud of it. Taught myself some neat new tricks while doing it, too!) www.cell.com/cell-genomic...

Reporting and representation of population descriptors in public RNA-seq databases

By combining repository metadata, genotype-inferred ancestry, and manual curation of publications, Gallego Romero et al. demonstrate that public RNA-seq datasets are dominated by samples from high-inc...

cell.com

Our (@nebanovich.bsky.social , @tgenresearch.bsky.social) most recent work with @kamancherla.bsky.social and Dr. Ravi Shah at VUMC is out in Nature CVR! www.nature.com/articles/s44... 1/14

Dynamic cellular programs of human cardiac allograft rejection revealed by spatial transcriptomics - Nature Cardiovascular Research

Using spatial transcriptomics on longitudinal human cardiac biopsies, Amancherla, Oill and colleagues reveal marked cellular and molecular heterogeneity in transplanted hearts undergoing rejection, id...

nature.com

www.nature.com/articles/s44...

Dynamic cellular programs of human cardiac allograft rejection revealed by spatial transcriptomics - Nature Cardiovascular Research

Using spatial transcriptomics on longitudinal human cardiac biopsies, Amancherla, Oill and colleagues reveal marked cellular and molecular heterogeneity in transplanted hearts undergoing rejection, id...

nature.com

TGen@tgenresearch.bsky.social · 2mo ago

Standard biopsies can't capture the full picture of heart transplant rejection. A new study from TGen and Vanderbilt Health in @nature.com Cardiovascular Research uses spatial transcriptomics to map gene expression at the cellular level. Key takeaways... 1/3

New study from our group in collaboration with Ravi Shah. Led by @angela-oill.bsky.social and @kamancherla.bsky.social. www.nature.com/articles/s44...

Dynamic cellular programs of human cardiac allograft rejection revealed by spatial transcriptomics - Nature Cardiovascular Research

Using spatial transcriptomics on longitudinal human cardiac biopsies, Amancherla, Oill and colleagues reveal marked cellular and molecular heterogeneity in transplanted hearts undergoing rejection, id...

nature.com

@saahimall.bsky.social sharing her journey!

TGen@tgenresearch.bsky.social · 4mo ago

Can one summer change your entire future? For 20 years, the Helios Scholars Program at TGen has been doing just that for Arizona students—turning summer break into a launchpad for top-tier STEM careers. 🧬🚀 https://bit.ly/4ulK3Wh #Genomics #Arizona #Biotech #Internship

The White House Office of Management and Budget is moving to take more control of billions of dollars in federal grants. Critics say the proposed change would jeopardize the integrity of U.S. science. n.pr/4uNA78T

President Trump seeks control of science funding

The White House Office of Management and Budget is moving to take more control of billions of dollars in federal grants. Critics say the proposed change would jeopardize the integrity of U.S. science.

n.pr

BREAKING: New proposed OMB regulation, applying to all federal grants, requiring grant reviews by senior political appointees and re-emphasizes that "peer review remains advisory and does not replace agency discretion". #standupforscience public-inspection.federalregister.gov/2026-10817.pdf

Great work Floris! You’re on a role.

Floris Barthel@florisbarthel.bsky.social · 5mo ago

The human genome's most variable and clinically important regions (centromeres, telomeres, and acrocentric short arms) have been hardest to study at scale. Thrilled to share KaryoScope, our new preprint that brings them within reach. 🧵 www.biorxiv.org/content/10.6...

Great work from the Barthel lab! Happy to see this out in it's final version!

Nucleic Acids Research@narjournal.bsky.social · 5mo ago

⭐ #NARBreakthrough ⭐ New study delivers the first chromosome-level phased assemblies, uncovering >50,000 #structuralvariants and rescuing millions of #unmappable reads in BJ and IMR-90 human cell lines. 📖 Read here: doi.org/10.1093/nar/... #Genomics #CellLines #CommunityResource

New preprint! We used Oxford Nanopore long-read sequencing to ask: does chromosome-arm-specific telomere length shape how IDH-mutant astrocytoma genomes evolve? Short answer: yes, and in two opposite directions. 🔗 www.biorxiv.org/content/10.6...

It’s #earthday! Sad to see some of the most pristine parts of the US under threat for short term gains and political reasons. This pic I took in my fav part of the US on the Utah/AZ border.

Earth day. As it turns out Earth is one of my favorite places to hang out. All kidding aside I spend all the free time I can in the woods and on the rivers of the West. Unfortunately we’re facing headwinds for protecting these places in the US. We’ve got to take care of this place.

In diseases like Sarcoidosis Granulomas are ubiquitous and mysterious, and RIPE to be demystified by spatial omics analysis. Kudos @jonas_schupp for this groundbreaking work. Read paper at academic.oup.com/ajrccm/artic... #CureSarcoidosis

Spatial transcriptomics uncovers hybrid, proinflammatory, and profibrotic cellular niches in pulmonary granuloma of patients with chronic sarcoidosis

AbstractBackground. Sarcoidosis is a disease of unknown etiology, characterized by the formation of immune cell accumulations (granulomas) in the lung and

academic.oup.com

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

Friends and Colleagues! I am SO excited to catch up with you all this week at #AABA2026! Here is a quick 🧵summarizing what our 🧪🧬👩🏽‍💻👨🏿‍🔬👩🏼‍🔬🧑‍💻lab will be presenting at the meetings (1/n) @umncla.bsky.social @umnanth.bsky.social www.nievescolonlab.org

Anthropological Genetics Lab at UMN

Anthropological Genetics Laboratories at the University of Minnesota Twin Cities

nievescolonlab.org

Excited to share new preprint with NVIDIA on GPU-accelerated single-cell analysis 🚀 rapids-singlecell brings native GPU support to scverse/AnnData: hours → seconds (1M cells: ~52m → ~25s), scaling to 100M cells. Huge thanks to Severin Dicks 🙌 📄 arxiv.org/abs/2603.02402

See thread from @jeremymberg.bsky.social from today that takes a whack at estimating FY2025 success rates by IC.

Drug Monkey@drugmonkey.bsky.social · 7mo ago

NIH has not updated the overall success rates pages drugmonkey.wordpress.com/2026/03/12/n...

@ee-reh-neh.bsky.social capturing the difficulty of carrying out any sort of projects with a field component. So grateful to have been a part of this study.

Irene Gallego Romero@ee-reh-neh.bsky.social · 7mo ago

First, a couple of weeks ago: www.biorxiv.org/content/10.6... Single cell RNAseq on blood from 200 donors across 4 sites in Indonesia spanning regional axes of genetic and environmental diversity. This is one of very few scRNA data sets from the Global South, including urban and rural settings.

Very excited to see this work be the first to use the quasar method for eQTL mapping!

Irene Gallego Romero@ee-reh-neh.bsky.social · 7mo ago

First, a couple of weeks ago: www.biorxiv.org/content/10.6... Single cell RNAseq on blood from 200 donors across 4 sites in Indonesia spanning regional axes of genetic and environmental diversity. This is one of very few scRNA data sets from the Global South, including urban and rural settings.

Register now for March 2nd @agbt.bsky.social Recap! Inside AGBT: Big Announcements and Bigger Implications www.genengnews.com/multimedia/i... Featuring @jlemieux.bsky.social @biomath.bsky.social @jasmineplummer.bsky.social @nebanovich.bsky.social Catherine Aquino

Inside AGBT: Big Announcements and Bigger Implications

On this episode of GEN Live, we deliver a full debrief on the news from AGBT—critical to understanding where NGS, spatial, single-cell, and multiomics are headed.

genengnews.com

Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share. Tldr: scRNA-seq in Indonesia hard but fun

bioRxiv Genomics@biorxiv-genomic.bsky.social · 8mo ago

Ancestral and environmental diversity shape the immune landscape in Indonesia https://www.biorxiv.org/content/10.64898/2026.02.15.704933v1

So excited to have this study live! Lead by @ee-reh-neh.bsky.social's teram and in collaboration with an incredible team at MRIN in Indonesia. This is the culmination of ~5 years of work including a ton of effort in the field. Really proud of how this came together! www.biorxiv.org/content/10.6...

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.

The fact of the matter is: a severe #IceStorm is developing across much of the country at this very moment, with potentially devastating and far-reaching consequences extending far beyond the region of maximum #ice concentration. Watch out for the #ice, and help your neighbors weather the storm.

Acyn@acyn.bsky.social · 8mo ago

CNN: DHS officials have come to FEMA staff and told them to limit the use of the word ice…they are worried that by posting something like, watch out for the ice, that it's going to become a meme….

My (now) weekly update on 2026 NIH funding. New and competitive renewal awards. 3 new awards (compared to ~100 expected based on recent years). No new ICs... still just NIA, NINDS, NIDCD, and NIDCR. 1/2

Use of SNPs in a low diversity system for genetic monitoring and identifying a successful translocation event in the Paiute Cutthroat Trout (O. henshawi seleniris) https://www.biorxiv.org/content/10.64898/2026.01.07.697447v1

A fun little project. We were curious if you could prep a single sample using both 10X Genomics Xenium V1 probes and Prime probes – allowing users to profile 480 genes at high sensitivity and 5,000 genes at lower sensitivity inline. www.biorxiv.org/content/10.6...

Fishing with Two Lines: A Hybrid Approach to Spatial Transcriptomic Discovery

Spatial transcriptomics faces a trade-off between the number of genes assayed and depth of per-gene sensitivity. We developed a 'dual chemistry' method that combines the high sensitivity of a 10X Geno...

biorxiv.org

Great new work led by Aaron Kwok from @davisjmcc.bsky.social’s group. A tool to “denoise” contaminating transcripts from image based spatial data. www.biorxiv.org/content/10.1...

Denoising image-based spatial transcriptomics data with DenoIST

Image-based spatial transcriptomics (IST) technologies provide unprecedented resolution of gene expression in tissue sections, but suffer from contamination of cells' gene expression profiles due to i...

biorxiv.org

🚀 We’re thrilled to announce our new partnership with SOPHiAGENETICS! Together, we’re redefining what’s possible in #sequencing—delivering richer insights, faster results, and greater accessibility for labs everywhere. 🔗 Learn more: https://bit.ly/4nNmOks #Genomics #Genetics

SOPHiA GENETICS and Element Biosciences Unite Sequencing Power and AI Analytics to Accelerate Global Research In Precision Medicine

SOPHiA GENETICS and Element announce a partnership to unite sequencing and AI analytics to streamline genomic workflows and accelerate research in precision medicine

bit.ly