Excited to kick off #HAICON26 today! 🚀🤖 More than 600 participants joining us to explore how AI is transforming science and accelerating discovery. Great energy, great people, and an exciting program ahead. 👉 haicon.cc #AIforScience #HAICON26

1/5 Cell identity is written in the proteome, not in the DNA, and not always in the RNA. Out on bioRxiv today: The first cell type-resolved, MS-based proteomic atlas of the human body. www.biorxiv.org/content/10.6...

Beautiful short Nature Methods N&V “Teaching an old dog new cells” led by J Linder & D Kelley. Also on scooby, pushing seq2func models toward true cell-state–specific reg modeling 🧬 Fitting disc here at CSHL with Anshul & others on this next frontier www.nature.com/articles/s41...

Structured disentanglement, now published in "Cell Systems" www.cell.com/cell-systems... @cp-cellsystems.bsky.social @cellpress.bsky.social Proud to have built this with Aleyna Kara, Antony Rose, Muzlifah Haniffa (@mhaniffa.bsky.social), and Fabian Theis (@fabiantheis.bsky.social).

TarDis: Achieving robust and structured disentanglement of multiple covariates

Inecik et al. introduce TarDis, a deep generative model that disentangles multiple covariates in single-cell genomics into structured latent spaces. By jointly modeling categorical and continuous fact...

cell.com

Excited to share that UniversalEPI is officially published in @narjournal.bsky.social! 🚀 Check out the final paper and use the model here: 📄 Paper: academic.oup.com/nar/article/... 💻 Code: github.com/BoevaLab/Uni... (1/3) 🧵

Valentina Boeva@valboeva.bsky.social · 2y ago

🚀 New preprint from our lab, Ekaterina Krymova, and @fabiantheis.bsky.social: UniversalEPI, an attention-based method to predict enhancer-promoter interactions from DNA sequence and ATAC-seq🌟 Read the full preprint: www.biorxiv.org/content/10.1... by @aayushgrover.bsky.social, L. Zhang & I.L. Ibarra

50 today 🎉 Feeling a tad older, but mostly very grateful: to family, friends, colleagues, collaborators, and students for the journey so far! Huge thanks to my department for the amazing surprise reception today. You certainly know how to celebrate science & aging in style 😄🚀

Enjoying inspiring discussions with colleagues & friends at the GRC Single Cell Genomics conference in Les Diablerets, surrounded by an awe-inspiring mountain landscape. Special setting for maybe grand ideas!

Excited to share our RegVelo paper in Cell www.cell.com/cell/fulltex... We unify RNA velocity + GRNs into one model → better OOD prediction of perturbations (e.g. gene KOs), with examples incl. neural crest KO predictions 🔬 Big thanks to W Wang, Z Hu & T Sauka-Spengler 🙏

New preprint with Garnett lab 🚀: from descriptive → causal single-cell atlases in CRC.We build the largest CRC atlas (>300 pts, 1.5M cells) using continual learning, and link cell states to causal drivers via Tahoe-100M, validated in organoids! www.biorxiv.org/content/10.6...

Excited to share our cross-species PDAC atlas preprint led by D Lucarelli & S Parikh in collab with D Saur: www.biorxiv.org/content/10.6... 1.6M single cells (human + mouse) to quantify how well models capture disease 🧬 Core programs are conserved, even rare immune pops clearly aligned.

Great to be at Roche’s new Institute for Human Biology (IHB) in Basel. Spoke on 'virtual organoids' & predictive models. Inspiring talks from Paola Arlotta, Amy Shyer & Mark Fishman. Exciting convergence of biology, engineering & AI - congrats to Roche on this bold initiative!

At Novartis Campus Basel yesterday for our 2nd Helmholtz Munich × Novartis workshop on advancing AI + multi-modal kidney disease research, from cross-species atlases to targets. Thanks Caroline Gubser-Keller & team for great discussions! www.helmholtz-munich.de/en/icb/news-...

Helmholtz Munich Launches Collaboration on AI-Driven Kidney Disease Research

Helmholtz Munich and Novartis Biomedical Research are launching a four-year collaboration to advance kidney disease research. Starting in early 2026, the partnership will work to develop an…

helmholtz-munich.de

Excited to share new preprint with NVIDIA on GPU-accelerated single-cell analysis 🚀 rapids-singlecell brings native GPU support to scverse/AnnData: hours → seconds (1M cells: ~52m → ~25s), scaling to 100M cells. Huge thanks to Severin Dicks 🙌 📄 arxiv.org/abs/2603.02402

🚀 New in Communications Biology: Generative models of cell dynamics - from Neural ODEs to Flow Matching www.nature.com/articles/s42... We discuss modeling single-cell dynamics beyond snapshots: from cont-time Neural ODEs to simulation-free flow matching for scalable pop modeling.

Hazel Brugger moderating Google Berlin AI Center Evening party - not just entertaining but compelling w eg Minister D Bär on Germany‘s High Tech Agenda pushing Ai for health, biotech & energy!

🚀 Opening of the Google AI Center Berlin - a strong signal for AI in Europe. Great to join Minister K Wildberger, Mayor K Wegner, Yossi Matias and others to discuss AI in science. Proud that our Helmholtz Munich & TUM teams presented joint work on AI for health!

🗞️ At 'Digitalgipfel' of Süddeutsche Zeitung: www.sz-gipfel.de/digitalgipfel Germany's Digit. Minister Karsten Wildberger just outlined plans for unified citizen app & digital wallet 🇩🇪, finally! Me contributing to “KI konkret”, about how AI revolution is well underway in biomed.

How to learn gene regulation patterns from multimodal single-cell data? To answer this question, we at OpenProblems organised the Kaggle competition on modality prediction. It ran back in 2022 but still remains the world's largest competition in the single-cell field. 1/17

At the 132nd Internat. Titisee Conference on Biology 2.0: The AI Revolution in Biology & Medicine From sequence→function models 🧬 to protein & generative structure models 🧪 to AI of cell states & perturbations 🧫 Great science, great friends, beautiful lake. Thanks @BIFonds!

Join us at the #CellPressSymposia: Decoding cellular complexity: Single cell biology in the era of AI, Dec 2–4, 2026, Munich, Germany, in partnership with @helmholtzmunich.bsky.social. #CPSsinglecellbiology2026 @ethz.ch.bsky.social http://dlvr.it/TR8Rw9

Join us at Cell Symposia: Single-Cell Biology in the Era of AI (Dec 2–4, 2026, Munich) 🇩🇪 From multi-omics to AI-driven models of cellular dynamics — an exciting lineup across experimental & computational biology. Hope to see you there! 🔗 www.cell-symposia.com/single-cell-...

Home – Cell Symposia: Decoding Cellular Complexity: Single Cell Biology in the Era of AI

Cell Symposia: Decoding Cellular Complexity: Single Cell Biology in the Era of AI

cell-symposia.com

Looking forward to tonight’s Synapse Munich fireside chat 🔥 Great to connect with the Munich AI x biotech community. Thanks to Nucleate and Amino Collective for the invitation! See you there 🚀 luma.com/ehl0ap32

Synapse Munich · Luma

Invite-only get-together with engineers, founders and scientists building at the intersection of AI, health & bio. Expect drinks, food, and some real talk…

luma.com

🚀 From modality-specific to compositional foundation models for cell biology Happy to share our new Perspective in Cell Systems. We describe an emerging shift toward compositional multimodal architectures 🧩 authors.elsevier.com/c/1mdzg8YyDf...

Munich takes the top two spots in the FT ranking of Europe’s startup hubs — UnternehmerTUM #1, Start2 Group #2. Strong science, engineering depth, & real bridges between research + entrepreneurship. Huge opportunity ahead in part. for AI + bio/med. 🚀 www.ft.com/content/ab05...

FT ranking: Europe’s leading start-up hubs 2026

View the top centres providing business incubator and accelerator programmes

ft.com

Honored to receive today the official membership document of the @Leopoldina – Germany’s National Academy of Sciences – in Halle. “Nunquam otiosus” – never idle. A reminder that science is a continuous responsibility. And proud to be elected together with my AI & ELLIS colleague Sepp Hochreiter.

Where tech meets politics. At the #MSC Startup Hub, innovation & geopolitics collide in real time. Our @Helmholtz_de President Martin Keller is chairing session with former MI6, FBI/Interpol & Ukrainian security leader. Clearly security, crypto & AI are strategic capabilities.

🚀 New preprint: population-aware single-cell dynamics Collab w/ Bertie Göttgens’ lab, led by Weizhong. pseudodynamics+ goes beyond pseudotime to infer birth/death, differentiation & interpolate time in scalable fashion - directly from snapshot scRNA-seq. 👉 www.biorxiv.org/content/10.6...

CellRank protocol now in @NatureProtocols! 🎉 @PhilippWeiler's detailed guide shows how to: - Integrate velocity, pseudotime & time points - Infer cell fate probabilities - Analyze lineage priming at scale Great complement to our CellRank 2 paper! 📖 www.nature.com/articles/s41...

Did you catch our recent Protocol describing the inference of cell fate from single-cell RNA sequencing data using CellRank? 🧪 @natprot.nature.com @fabiantheis.bsky.social

CellRank: consistent and data view agnostic fate mapping for single-cell genomics - Nature Protocols

CellRank enables cell fate mapping from single-cell RNA sequencing data in a consistent and scalable manner, relying on different views of the data such as pseudotime or stemness potential, RNA veloci...

nature.com

A recent @derspiegel article on “one of Germany’s most renowned AI researchers” got me thinking. The person was new to me, but I think highlights a somewhat recurring issue: media visibility is not the same as scientific contribution. www.spiegel.de/wissenschaft...

(S+) Joscha Bach: Wie ein deutscher Forscher mit Epsteins Hilfe Karriere machte

Joscha Bach ist einer der renommiertesten deutschen KI-Forscher, offenbar hat er mehr als eine Million Dollar von Jeffrey Epstein erhalten. SPIEGEL-Recherchen zeigen: Der Kontakt reichte weit ins…

spiegel.de