DUBE-Lab
@dubelab.bsky.social
@fau.de Pursuing nanotechnology with chemistry and light. Research in molecular machines, photoswitches, supramolecular chemistry, photopharmacology, and smart materials. https://www.chemistry.nat.fau.eu/research/research-groups/dube-group/dube-group/
Ein Medikament soll möglichst nur dort wirken, wo es gebraucht wird. In der Realität ist das schwierig. Deswegen wollen Forschende der FAU die Wirkung eines Stoffes nun von außen kontrollieren – und zwar mit Licht. Mehr erfahren: www.fau.de/2026/08/news...
Ein Schweizer Taschenmesser für die Zelle
Forschende der FAU verbinden Chemie und Zellbiologie zu einem neuartigen Werkzeug für die biomedizinische Forschung…
fau.de
Excited to share that our review has been published in @angewandtechemie.bsky.social ! We summarize recent advances in deep-red to near-infrared light-driven radical generation and discuss future opportunities for low-energy photochemistry. doi.org/10.1002/anie...
Low‐Energy Photons in Radical Chemistry: From Deep‐Red to Near‐Infrared Radical Generation for Organic Synthesis
Low-energy photons from deep-red (DR) to near-infrared (NIR) light offer unique opportunities for sustainable photochemical synthesis but suffer from intrinsically limited reactivity. This Review sum...
doi.org
Proud that our work was published in JACS! 💫🧪🧫 This was a fruitful collaboration with the @dubelab.bsky.social. A true interdisciplinary effort to build multifunctional light controllable molecules for biomedical applications and future drugs. Amazing job by Manuel Valentin and David Féval! 👏
A Multifunctional and Secure Photoresponsive Proteasome Inhibitor to Control Cell Fate
Abstract. Precise external control of biological processes represents a central interest in the life sciences. Specifically designed molecular tools are id
pubs.acs.org
Our advanced photopharmacology approach for multi-functional caged proteasome inhibitors is out in JACS! Nice collaboration by @zaninlab.bsky.social and @dubelab.bsky.social! A Multifunctional and Secure Photoresponsive Proteasome Inhibitor to Control Cell Fate pubs.acs.org/jacsat/artic...
A Multifunctional and Secure Photoresponsive Proteasome Inhibitor to Control Cell Fate
Abstract. Precise external control of biological processes represents a central interest in the life sciences. Specifically designed molecular tools are id
pubs.acs.org
Totally excited to share our newest all visible and NIR-light rewritable four-colour systems enabling all natural color 2D and 3D displays! Huge milestone for all-photonic multi-responsive materials: check it out at: chemrxiv.org/doi/full/10....
So honoured to be the opening speaker at ISOP 2026 in Groningen! A real family reunion, tried to make it a wholesome 3D experience, 1950s cinema style. Will bring more next time! Thanks so much to Nathalie, Wiktor, Wesley, Tibor for organising and Ben Feringa for chairing! isop20206.eu
Another Highlight about our work on a supercharged molecular motor in @natchem.nature.com! We are really honoured, thank you so much Emma and Jos!!
Nature Chemistry@natchem.nature.com · 2mo agoSerendipitous twist in a hemithioindigo molecular motor enables energy storage #chemsky
Our supercharged molecular motor is highlighted in a new Nature Chemistry Editorial - thank you so much!!!
Nature Chemistry@natchem.nature.com · 2mo agoSetting a direction for molecular motors #chemsky
Check out our latest publication on a new peace of molecular machinery published in @jacs.acspublications.org! Fantastic work by Lilli and Nico!! Photoswitchable Molecular Spur Gears: An Entry Point to Motorized Gearing | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...
Photoswitchable Molecular Spur Gears: An Entry Point to Motorized Gearing
Molecular gears represent fundamental archetypes of molecular machines as they provide crucial capacity in redirecting, translating, and rate-shifting of nanoscale motions. Most prevalent are thermall...
pubs.acs.org
Great to connect within the VolkswagenStiftung-Cosmos - even quite literally :-). Really appreciate the entrepreneurship and dedicated support for stepping out-of-the-box and trying something new!
VolkswagenStiftung@volkswagenstiftung.de · 3mo ago#Vernetzen, Kooperationen ausloten, Herausforderungen in einer wissenschaftl. Karriere diskutieren: 👉 Letzte Woche fand unser 27. Gefördertentreffen statt. Eine wertvolle Gelegenheit ins Gespräch zu kommen. ✨ Personenförderung bedeutet für uns, diejenigen zu fördern, die #Wissenschaft neu denken.
Our 900 nm NIR photoswitch for invisibly writable 2D and 3D displays is out as VIP paper in @angewandtechemie.bsky.social! check it out here: onlinelibrary.wiley.com/doi/full/10....
A Reversible 900 nm Near‐Infrared Photoswitch for Invisibly Writable 2D and 3D Displays
The peri-benzo[a]fluoranthenethioindigo (PBFT) photoswitch enables direct excitation with near-infrared light up to 900 nm wavelengths. It delivers a high-performance property profile including high-....
onlinelibrary.wiley.com
New molecular motor incoming! We proudly present a different type of light-driven motor – it is fast, it moves by a unique mechanism, and it stores a lot of light energy. Check out our newest and supercharged molecular machine at @natchem.nature.com - great collab with Carolin Müller lab!
Nature Chemistry@natchem.nature.com · 3mo agoA supercharged molecular motor operating by constitutional alteration and proton transfer #chemsky
Prestigious Funding for our new materials research topics! Fantastic opportunity to venture into new fields supported by the @volkswagenstiftung.de!
FAU Erlangen-Nbg@fau.de · 5mo agoKünstliche Muskeln mithilfe von winzigen molekularen Maschinen herstellen: Prof. Dr. Henry Dube (FAU) möchte Materialien für völlig neue Anwendungen entwickeln. Diese könnten durch Licht gesteuert werden und programmierbar sein. Das Projekt wird mit mehr als 900.000€ gefördert: go.fau.de/1dife
photopharmacology fun: add photonic capabilities to your proteasome inhibitors!
ZANIN LAB@zaninlab.bsky.social · 5mo agoNew Paper Alert! 💥 Check out our next generation multifunctional proteasome inhibitor controlled by light. A versatile and customizable chem-bio tool for steering cell fate. Congratulations to David and Manuel from the @dubelab.bsky.social on this fruitful interdisciplinary collaboration! 🧪 🔬
Molecular confinement enables chiroptic enhancement and ECD photoswitching. Our newest work on advanced photonic functions is published in Chem! Huge effort from Fabien and the team – we are so proud of you! authors.elsevier.com/sd/article/S... @cp-chem.bsky.social @fau.de
Exciting chemsky work out First Release in @science.org from @gracegdhan.bsky.social and collaborators, scrunching up pyrimidones so tight with UV light that the strain release can boil water! www.science.org/doi/10.1126/...
Molecular solar thermal energy storage in Dewar pyrimidone beyond 1.6 MJ/kg
Storing sunlight in a compact and rechargeable form remains a central challenge for solar energy utilization. Molecular solar thermal (MOST) energy storage systems, which harness photon energy and rel...
science.org
There's a new motor in town! 🏎️ 🔬 Out in @natchem.nature.com , our latest study introduces a light-driven diazene molecular rotary motor able not only to achieve directional motion, but also to invert the rotation by varying the colour of the light supplied. www.nature.com/articles/s41...
Wavelength-steered directional rotation in an autonomous light-driven molecular motor - Nature Chemistry
The rational design of autonomous light-powered molecular motors remains a formidable challenge in nanoscience. Now, a photochemically driven diazene-based rotary motor has been shown to rotate around...
nature.com
Bravo Jeanne! 👏👏👏 @jeannecrassousiscr.bsky.social
ISCR - Institut des Sciences Chimiques de Rennes@iscr-rennes.bsky.social · 8mo ago🏆 Congratulations👏 to @jeannecrassousiscr.bsky.social laureate of Chirality Medal 2026. This prize is awarded in recognition of her whole career dedicated to #chirality ➡️ iscr.univ-rennes.fr/jeanne-crass... 🤝 @rennesuniv.bsky.social @cnrs-bretagneloire.bsky.social #ENSCR @insarennes.bsky.social
Thrilled to report another milestone: 900 nm photoswitching enables NIR-light detection and reversible invisible writing of high-contrast 2D and 3D displays! Check out our newest molecular photoswitch PBFT (peri-benzo[a]fluoranthenethioindigo) at ChemRxiv - doi.org/10.26434/che...
Our work on the unidirectional motion of a CD is now in the September issue of Chem and on the cover! Many thanks to the whole team and @cp-chem.bsky.social for the highlight! @ipcm-sorbonne.bsky.social @msollogoub.bsky.social @enxuliu.bsky.social www.cell.com/chem/fulltex...
In this piece for Aeon, I argue that, while nanotechnology is now a very real and mature field, a popular early vision of it was an example of what I am calling an "oneiric technology": a fantasy of the sort that Silicon Valley loves. aeon.co/essays/no-su...
No suffering, no death, no limits: the nanobots pipe dream | Aeon Essays
Thirty years ago, nanotech was about to change everything. Let’s not get tricked again by Silicon Valley’s magical thinking
aeon.co
Joyful day for the lab! 🎉 🥳💫🍻 Fritzi defended her PhD thesis with outstanding honors. Congratulations on this amazing thesis! Here is a list of some of her projects: onlinelibrary.wiley.com/doi/full/10.... pubs.acs.org/doi/10.1021/... www.cell.com/cell-reports... www.biorxiv.org/content/10.1...
On the cover of this week's issue: "Photoswitchable Fluorescence of Peptide-Based Hemipiperazines Inside of Living Cells" Read it here 🔗: buff.ly/tQkMt7v #ChemSky #JACS
I‘m thrilled to see our group‘s inaugural paper published in @science.org! Huge thanks to everyone who contributed to this project!
Science Magazine@science.org · last yr.This week in Science, researchers report an artificial molecular motor that can twist a molecular thread to form a mechanically interlocked molecule. The approach creates opportunities to fabricate mechanically interlocked molecules with precise structural control. Learn more: scim.ag/40FboGP
Our pipeline to compute thermal barriers of photoswitches💡 is out!🥳 We especially focused on NBDs for MOST🔋 and imines, but also stilbenes and DAEs. Try it out! You need just chemdraws and freeware to get libraries computed doi.org/10.1002/cptc...
Semi‐Automated Pipeline for Transition State Search of Molecular Photoswitches
A semi-automated pipeline for the transition state search of molecular switches (PiTS3) is reported, which facilitates the search, optimization, and conformational analysis of transition states of ph...
doi.org
A new photocaging strategy bringing boronic acids under photo-control! Boronic-Acid Photocaging for Visible Light-Controlled Applications in Synthesis | ChemRxiv - doi.org/10.26434/che...
It was a great pleasure to host Prof. Paolo Melchiorre for his brilliant #GDCh lecture at @nat.fau.de! Paolo’s talk highlighted how core #photochemical insights spark innovation in #AsymmetricSynthesis! @gdch.de @dubelab.bsky.social @spanlabfau.bsky.social @harder-research.bsky.social
What a fantastic outing with our Organic Chemistry Institute today – an amazing team and a great atmosphere all around!! 🚣♂️👍 @dubelab.bsky.social @ekatl.bsky.social @nat.fau.de @fau.de
Honored to receive the #RSCPrizes Corday-Morgan Mid-Career Prize for Chemistry. Credit has to go to the hard work and creativity of many outstanding researchers over 10 years at 3 institutions (@qmul.bsky.social, @unisouthampton.bsky.social, @unibirmingham.bsky.social). Short🧵
