A nice follow-up to our recent @nature.com paper (@barbmarte.bsky.social). Nature has published a News & Views piece discussing the work: “The secret life of a cell-cycle gatekeeper of cancer.” Very proud of the team. Interested to hear where these concepts go next. www.nature.com/articles/d41...

The secret life of a cell-cycle gatekeeper of breast cancer

A newly discovered function for the protein Rb explains why inhibiting cell division can enhance the signalling mediated by the oestrogen receptor that drives breast cancer.

nature.com

CDK4/6 inhibitors, a cornerstone treatment for advanced HR+ breast cancer, were thought to work by reactivating Rb, a tumor suppressor that puts the brakes on cancer cell growth. In @nature.com, ASPIRE Awardee @shomgoel.bsky.social shows that isn’t the full story. www.petermac.org/about-us/new...

new out in @nature www.nature.com/articles/s41...

Thank you @petermaccc.bsky.social We are very proud to work in one of the world's best cancer research hospitals.

Peter MacCallum Cancer Centre@petermaccc.bsky.social · 2mo ago

Peter Mac researchers from @shomgoel.bsky.social's lab have uncovered why breast cancer treatment stops working for some patients. Published in Nature, the discovery could help develop new treatment combinations that work for longer and improve outcomes. More: www.petermac.org/about-us/new...

Peter Mac researchers from @shomgoel.bsky.social's lab have uncovered why breast cancer treatment stops working for some patients. Published in Nature, the discovery could help develop new treatment combinations that work for longer and improve outcomes. More: www.petermac.org/about-us/new...

Delighted to share our new paper, published today in @nature.com , led by April Watt and Antonio Ahn at the @petermaccc.bsky.social and @unimelb.edu.au

Congratulations to Olivia Voulgaris - an Honours student in our lab co-supervised by Stephin Vervoort - who was awarded the 2025 Nicole Lundie Prize, recognising her as the most outstanding Honours student at Peter Mac @petermaccc.bsky.social! A truly brilliant student with infectious enthusiasm!

A very fast moving area: we now have more post-CDK4/6 options than clear biological principles for choosing among them. Looking forward to discussing this at #SABCS25 @sabcs.bsky.social @elmayermd.bsky.social

San Antonio Breast Cancer Symposium@sabcs.bsky.social · last yr.

After CDK4/6 Inhibitors: Advancing Treatment for HR+HER2-negative Metastatic Breast Cancer— Mafalda Oliveira, Erica Mayer, and Shom Goel will address this topic in an educational session at #SABCS25 (December 9-12). Learn more: buff.ly/0YYiXTa

Looking forward to SABCS this year @sabcs.bsky.social. Especially excited that April Watt @aprilwatt.bsky.social will give an oral presentation in General Session 3, highlighting our lab’s work on new epigenetic roles of Rb. Program: sabcs.org/events/gener... #SABCS25