Excited to share our new paper in @brainbehavimm.bsky.social, exploring how the dynamics of the inflammatory response around stressors relate to later neuropsychiatric and somatic outcomes: www.sciencedirect.com/science/arti...

Dynamics of the systemic inflammatory response surrounding stressors and the association with neuropsychiatric and somatic outcomes

Acute and chronic stressors contribute to neuropsychiatric disorders. However, the role of inflammatory dynamics around stress exposure remains unclea…

sciencedirect.com

Chronic Idiopathic Urinary Retention/ Fowlers syndrome is common in FND and vice versa. A new framework for non-surgical treatment, led by @IngridHoeritza1 & Sara McRae, is a step change toward reducing permanent urinary catheters and invasive surgery. zurl.co/LyaMB

What is life? Final version is out @blaiseaguera.bsky.social Reed Bender, Karina Kofman link.springer.com/article/10.1... 🧪

What Lives? A Meta-Analysis of Diverse Opinions on the Definition of Life - Biological Theory

The question of "what is life?" has challenged scientists and philosophers for centuries, producing an array of definitions that reflect both the mystery of its emergence and the diversity of discipli...

link.springer.com

Sharing NeuroImage: Clinical issue on #FND. Includes 12 articles [11 original research papers]. Authors from Italy, Germany, Czech Republic, Norway, Canada, Spain, Switzerland, Australia, & the US. Editorial by #SelmaAybek, #KasiaKozlowska & I below. www.sciencedirect.com/science/arti...

We looked at a global cohort of >145,000 patients with a record of FND in the last 30 ys in TriNetX: confirmed frequent comorbidities and outcomes often worse than in MS. Read in JAMA Neurology: tinyurl.com/yc4wfyaj Open access to the accepted manuscript: osf.io/rwtnp @fndsociety.bsky.social

Comorbidities and Outcomes in People with Functional Neurological Disorder

This cohort study compared the prevalence of neurological comorbidities among people with functional neurological disorder versus those with epilepsy and multiple sclerosis.

jamanetwork.com

To lump or to split? That is the question. Here’s one study in favor of “lump”!

medRxivpreprint@medrxivpreprint.bsky.social · 6mo ago

The Case Against the 'S': Is Functional Neurological Disorder(s) One Condition or Many? https://www.medrxiv.org/content/10.64898/2026.03.19.26348846v1

Our new article highlights the presence and possible impact of cognitive symptoms in people with functional seizures or motor symptoms, also showing specific performance difficulties in attention and set-shifting in these #FND subgroups. Grateful to the team and participants🙏 doi.org/10.1017/S003...

Interesting research into the prevalence and persistence of sensory symptoms in those living with motor FND compared to those living with stroke. Well done @jonstoneneuro.bsky.social, Prof. Mark Edwards, Dr. Jan Coebergh, @roryhigginsphysio.bsky.social, @gnielsenphysio.bsky.social. #FND #Stroke

Rory Higgins@roryhigginsphysio.bsky.social · 7mo ago

Delighted to report our study on sensory symptoms has been published in @braincomms.bsky.social - @jonstoneneuro.bsky.social, Prof. Mark Edwards, Dr. Jan Coebergh, @roryhigginsphysio.bsky.social, @gnielsenphysio.bsky.social academic.oup.com/braincomms/a...

Delighted to share our paper in @braincomms.bsky.social: Clinical and demographic associations of recorded feigning in functional neurological disorder academic.oup.com/braincomms/a... Using a large international EHR database, we examined how often, and to whom, feigning codes are applied in FND.

Clinical and demographic associations of recorded feigning in functional neurological disorder

Analysing electronic health records, Berlot et al. found 2.2% of functional neurological disorder cases also had recorded malingering or factitious disorde

academic.oup.com

Professor Jernej Ule @ulelab.bsky.social, School of Neuroscience and @crick.ac.uk, teamed up with molecular biology and cancer experts to use his expertise on mRNA 🧬 to understand how to turn our immune system 🤧 on and off. 🔗 Read more: www.kcl.ac.uk/news/a-balan...

This is great - a really nice overview of recent FND network studies, and a friendly introduction to predictive processing theory in FND 🙌

David L Perez MD, MMSc@davidlewisperez.bsky.social · 8mo ago

Findings in this @biologicalpsych.bsky.social CNNI paper are complementary to other results published using graph theory metrics in @braincomms.bsky.social. Check out this 20 minute lecture by Christi Westlin that connects the two papers! 8/8 youtu.be/0Zjs-7lf6fA academic.oup.com/braincomms/a...

New-onset FND appears more likely after COVID-19 than other respiratory tract infections. Both the severity of the triggering illness and pre-existing individual vulnerability may contribute to the development of FND. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #FND @ean.org #WileyNeuro

I was asked by @braincomms to highlight their FND special collection which welcomes clinical and neuroscience research on every aspect of the condition. A chance to reflect on how FND has moved from miscellaneous to mainstream academic.oup.com/braincomms/a...

The Functional Neurological Disorder special collection in Brain Communications: bringing FND into the mainstream

Our Guest Editor, Jon Stone, introduces a special collection of articles focusing on functional neurological disorder.

academic.oup.com

Reclaiming FND for Rehabilitation Medicine – new open access editorial Neurorehab colleague Phil Milburn-McNulty and I set out why Rehab Medicine is so well-suited to treating FND, why they historically haven’t and what can be done to change things. journals.sagepub.com/doi/10.1177/...

Does COVID-19 increase the risk of FND? Find out in our paper, now published in the @europeanjournalofneurology.ean.org onlinelibrary.wiley.com/doi/10.1111/... Using EHR data from >2.7 million COVID-19 cases, we estimated the risk of new-onset FND within six months following infection.

Functional Neurological Disorder Following COVID‐19: Results From a Large International Electronic Health Record Database

Compared with other respiratory tract infections, the incidence of functional neurological disorder following COVID-19 is increased, with the risk higher in individuals with a more severe disease cou...

onlinelibrary.wiley.com

Resolving the Biomarker-Clinical “Mismatch” in Alzheimer's Disease www.linkedin.com/pulse/resolv...

Resolving the Biomarker-Clinical “Mismatch” in Alzheimer's Disease

A recent JAMA Neurology paper assesses the extent to which a measure of the tau protein in plasma known as p-tau217, drives the severity of Alzheimer’s disease, as measured by the Clinical Dementia Ra...

linkedin.com

📢 December issue now online featuring #asthma, #pneumonia, #sepsis, #epilepsy, #HIV, #PCOS, #depression, #UTI, and much more with our editorial on the future of prostate cancer screening …all available #free #OpenAccess❗️ Read more here: www.thelancet.com/issue/S2589-... Attribution: Getty #MedSky

While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset. 📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Did the late Mark Hallett crack the code underpinning the physiology of free will? Free will is the brain’s constructed awareness that we are choosing our actions even though the brain initiates them before we consciously know it. Mark Hallett was instrumental in describing how it all works.

Four yrs in the making, @greenjournal.bsky.social Practice Guideline Executive Summary on the Management of Functional Seizures. First @aanmember.bsky.social published guideline on any #FND variant. Brilliantly led by #BenTolchin. @fndportal.bsky.social www.neurology.org/doi/10.1212/...

Neurology® Journals

neurology.org

Psychiatric conditions show high comorbidity & genetic overlap, challenging diagnostic boundaries. @andrewgrotzinger.bsky.social et al applied cutting-edge statistical & functional genomics to 14 childhood- & adult-onset disorders (>1M cases) towards neurobiologically valid mental health nosology.👇🧪

Mapping the genetic landscape across 14 psychiatric disorders - Nature

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...

nature.com

Final version is out: authors.elsevier.com/c/1mEoa5bD-s... "Neural cellular automata: Applications to biology and beyond classical AI" @bhartl.bsky.social Léo Pio-Lopez

Excited to share our new paper in @eclinicalmed.bsky.social: www.thelancet.com/journals/ecl... In this retrospective cohort study, we examined 147,595 individuals with FND. We investigated the prevalence of adverse life events nd psychosocial stressors, and how these relate to FND presentations.

Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case–control study using a large international electronic health record database

A record of adversities was at least 2·5 times more common in FND than in migraine, and about 1·5 times more common than in GAD, varying by stressor type. Psychosocial stressors were particularly comm...

thelancet.com

To commemorate the bicentenary of Jean-Martin Charcot's life. Without him Neurology would be a different speciality. @uclqsion.bsky.social @brain1878.bsky.social @masudhusain.bsky.social academic.oup.com/brain/articl...

Charcot redux

Jean-Martin Charcot was born in Paris on 29 November 1825. To mark the bicentenary of his birth, the International Society for the History of the Neuroscie

academic.oup.com

Many neurological and mental health conditions may persist because homeostasis can lock the brain and body in stable patterns that are hard to shift. Have you tried switching it off and on again? osf.io/preprints/ps... Our new preprint explores the idea of a therapeutic reset.

A fantastic comprehensive review article w/ everything you need to know about Idiopathic Normal Pressure Hydrocephalus. Johnson and Williams share that idiopathic normal-pressure hydrocephalus is a common, frequently missed and potentially reversible neurologic condition in older adults. @nejm.org

@HarvardMedicine have done a great job with this article on FND, focused on the contribution of colleagues working there, including Barbara Dworetzky, David Perez and alumnus Mark Hallett. magazine.hms.harvard.edu/articles/fun...

📣 Abstract submissions open Wednesday, Dec 3! Submit your work for the 6th International Conference on Functional Neurological Disorder — June 13–16, 2026 in Baltimore. 🗓 Deadline: Feb 11, 2026 – 11:59 PM PST Details: www.fndsociety.org/biennial-meeting/2026/abstract 🌍 Please help spread the word!

How best to honor a giant and celebrate the late Mark Hallett’s legacy (1943-2025)? One way is for us to share his papers and teaching. This TMS Primer he wrote continues to be a big hit for all generations. @parkinsondotorg.bsky.social

💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #MECFS @ean.org #WileyNeuro