Neftaly Cruz Mireles

@neftalycm.bsky.social

Plant scientist 🌱🦠🧫 🇲🇽 | Postdoc at the University of Zurich in the Cyril Zipfel and Pedro Beltrao groups, studying protein phosphorylation during plant–microbe interactions #EMBOfellow | @thesainsburylab.bsky.social alumni

🌱New preprint 🎉 I am happy to share this last work of my PhD research! We uncover a novel role of cysteine protease RD19 in immunity. RD19 regulates RBOHD-generated ROS and is required for induced resistance responses. www.biorxiv.org/content/10.6... More details in the thread below! 🧵

Arabidopsis cysteine protease RD19 limits RBOHD-generated ROS production in pattern triggered immunity

Plants perceive pathogenic threats through receptors localized at the plasma membrane and inside cells to initiate pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), respectively....

biorxiv.org

5 years ago, @hacquardst.bsky.social and I became very interested in 𝑃𝑙𝑒𝑐𝑡𝑜𝑠𝑝ℎ𝑎𝑒𝑟𝑒𝑙𝑙𝑎 𝑐𝑢𝑐𝑢𝑚𝑒𝑟𝑖𝑛𝑎, an emerging fungal pathogen that colonizes the roots of many plants 🌱 🍅 🌾 🆕📝 Final result of a huge team effort to uncover the bases of its multi-host compatibility👇 www.nature.com/articles/s41...

Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts - Nature Microbiology

Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.

nature.com

I made a presentation to other faculty about recent progress in general AI, to facilitate the discussion around the impact for research and teaching in biology. It could be that the slides are useful for others trying to do that same. Feel free to re-use. docs.google.com/presentation...

generalAI_for research_intro.pptx

Recent AI developments and what they mean for us Quick primer on general AI models* State-of-the-art in AI agent capabilities AI agents in biology (examples) Discussion - what does this mean for our r...

docs.google.com

Sign up for the upcoming MechanoBioTalk by Neftaly Cruz Mireles (University of Zurich): "Defining protein phosphorylation networks at the plant–pathogen interface"- 16th September 2PM CET. Find the registration link and more information in our website: green-te.nl/activities/ @green-te.bsky.social

Activities - GreenTE

Activities Webinars ”MechanoBioTalks – Mechanics, Materials and Living Matter” is a webinar series supported by the GreenTE consortium and organized […]

green-te.nl

Thrilled to have the opportunity to investigate the role of membrane protein proteolysis in plant immunity through the ERC Starting Grant FRONTERA! A heartfelt thank you to my mentors, friends, and family whose support, encouragement, and guidance made this possible. #ERCStG @erc.europa.eu

European Research Council (ERC)@erc.europa.eu · last mo.

📣 Good news! 📣 Results of the ERC 2026 Starting Grant call are out! Funding worth a total of €705 million will go to 421 early-career researchers across Europe. Discover who, what and where 👉 link.europa.eu/9M3MmN 🧪 #ERCStG #FrontierResearch #HorizonEurope 🇪🇺 @scienceinnovation.ec.europa.eu

Thanks, Nef! It was an honour to visit the University of Zurich as a postdoc-invited speaker. Great to catch up with so many people. The Botanical Garden was amazing!

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Neftaly Cruz Mireles@neftalycm.bsky.social · 6mo ago

Thank you very much @tatsuyanobori.bsky.social for an inspiring talk at the Botanical Garden, Zurich last Friday. There is still so much to learn about plant immune responses at the single cell level! @thesainsburylab.bsky.social #IPMB #FridayForum

I’ll be talking today at the #Fungal26 concurrent session: AI in Fungal Research. I’ll be presenting on protein design in M. oryzae at 15:20 in the Fred Farr Forum. I’ll also be presenting my poster (#651A) tonight - come say hi!