“A p-value is the most widespread statistical concept that is not definable in a single sentence“ CHECKMATE
Stop trying to explain what a p-value is in a single sentence (ICYMI) statsepi.substack.com/p/no-you-can...
Mariano F. Zacarías-Fluck
@marianozf.bsky.social
Ph.D. in Biomedical Sciences, Senior Researcher @lsouceklab.bsky.social in Vall d'Hebron Institute of Oncology @VHIO.bsky.social , Barcelona. Amateur musician/genealogist/photographer. #Datavis lover. I sometimes don't follow but add to my lists 😊
“A p-value is the most widespread statistical concept that is not definable in a single sentence“ CHECKMATE
Stop trying to explain what a p-value is in a single sentence (ICYMI) statsepi.substack.com/p/no-you-can...
📣 New VHIO-@caixaresearch.bsky.social Scientific Seminar‼️ 🔹 Targeting clonal heterogeneity in treatment-refractory Glioblastoma with novel and empiric immunotherapies 👩🔬 Dr. Sheila Singh 🗓 Friday, 19th June at 12h 🎤 Host: Dra. Laura Soucek Register at 👉 scientific.seminars@vhio.net
What happens when researchers stop competing for funding? Twenty Dutch metascientists replaced competition with collaboration for NWO grant applications, proving collective approaches can outperform individual ones. @sajedehra.bsky.social @lakens.bsky.social www.tue.nl/en/news-and-...
What happens when researchers stop competing for funding? - tue.nl/stories | funding | open science | Daniel Lakens | Sajedeh Rasti
Twenty Dutch metascientists explore whether collaboration can outperform competition.
tue.nl
For years, #RAS and #MYC were considered "undruggable." The success of RAS has changed the conversation. Proud to see this recent @nature.com News & Views highlighting MYC as a promising next frontier and #Peptomyc as a key player helping advance the field. www.nature.com/articles/d41...
Landmark cancer trial shows success against ‘undruggable’ cancer — raising hopes for future treatments
Unprecedented results against a stubbornly hard-to-treat cancer are boosting optimism that other challenging tumours will be next.
nature.com
I just returned from two back-to-back conferences. Students, I noticed that a lot of your slide decks had an oddly similar layout structure and I was able to confirm in conversations that these were AI-generated/assisted. Some thought about this for your own professional development: 🧵
I'm using @proton.me (mail, storage), @duckduckgo.com (search, blockade of trackers on my phone) and Brave instead of the horrendous Chrome. I've been testing @asklumo.proton.me and to me, it works very well in general, not yet tested it for coding help. I can't wait to move away from Android!
Regular reminder that there are alternatives to Google Search and Google Chrome. Some European alternatives are listed here: european-alternatives.eu/alternative-... (where you can also find alternatives for other tech products should you be looking for them)
I'm usually not one to join the anti-AI hype train, but most of what I read this week was about AI degrading the scientific infrastructure I rely on heavily, from GitHub to arXiv to peer-reviewed published literature. Weekly Recap / Five Things: blog.stephenturner.us/p/five-thing...
Five Things (May 15, 2026): AI is why we can't have nice things
GitHub problems, vibe-coding regrets, Elsevier sues Meta, fabricated citations, the arXiv banhammer for AI-generated content
blog.stephenturner.us
📣 Last call‼️ Are you an #MD passionate about research? Fundació Catalunya La Pedrera #VHIO MD-PhD Fellowship is now open! 🚀 An excellent opportunity to become an expert in translational medicine 👉 https://linke.to/FellowshipPedreraVHIO2026 📅 Deadline: May 14th @cerca.cat
This is extremely concerning. #AI have the potential to be fantastic tools, but also to make us perhaps anxious or demanding for immediate results, curbing our own capacity for critical thinking and perseverance
New report of experimental evidence from Grace Liu & collaborators showing that AI assistance improves immediate performance - but after just ∼10 minutes of AI-assisted problem-solving people who lose access to the AI perform worse and give up more frequently than those who never used it.
New advising trick I've been trying: when a student looks skeptical about something, but doesn't *say* they are, I say "the look on your face says you don't believe me" I think explicitly acknowledging the nonverbal cue gives permission to voice what they're unsure about so we can talk about it
Charles Darwin was born on this day in 1809. A handwritten letter from Charles Darwin to Charles Lyell, 1861: “But I am very poorly today and very stupid and hate everybody and everything”
www.nature.com/articles/s41...
Tumour–brain crosstalk restrains cancer immunity via a sensory–sympathetic axis - Nature
Mouse models demonstrate that vagal sensory neurons transmit signals from lung adenocarcinoma to the brain, increasing sympathetic efferent activity in the tumour microenvironment and thereb...
nature.com
I had intended to post something about this new Google DeepMind paper that appeared yesterday in Nature, but the press coverage has added to what there is to say. So this is a long 🧵 www.nature.com/articles/s41...
Advancing regulatory variant effect prediction with AlphaGenome - Nature
AlphaGenome, a deep learning model that inputs 1-Mb DNA sequence to predict functional genomic tracks at single-base resolution across diverse modalities, outperforms existing models in variant effect...
nature.com
A very tidy blog entry on how to maintain a lab notebook. Easy to follow, super useful tips.
(I assume this is some of that: colinpurrington.com/tips/lab-not...)
The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system www.nature.com/articles/s41...
Analysis of 4841 papers accepted by NeurIPS 2025 show there are at least 100 with confirmed hallucinations 🙃 gptzero.me/news/neurips/
"While moderate levels of endogeny are common in special issues, excessive endogeny is a blatant case of scientific misconduct. We define special issues containing more than 33% endogeny as Published in Support of Self (PISS)... The large majority of guest editors engage in endogeny responsibly..."
PISS journals 😂 arxiv.org/abs/2601.07563
fantastic work from Fabio Giuntini and @lsoucek.bsky.social and @lsouceklab.bsky.social and a micro-collaboration from myself 😊. @vhio.bsky.social
MYC inhibition by Omomyc causes DNA damage and overcomes PARPi resistance in breast cancer
You know that thing Coco Chanel said about accessories? “Before you leave the house, look in the mirror and take one thing off” We should all do that but with about 50% of the text we put in slide decks. TAKE. IT. OUT.
Language models cannot reliably distinguish belief from knowledge and fact www.nature.com/articles/s42...
Reproducible processing of TCGA regulatory networks academic.oup.com/gigascience/... 🧬🖥️🧪
Reproducible processing of TCGA regulatory networks
AbstractBackground. Technological advances in sequencing and computation have allowed deep exploration of the molecular basis of diseases. Biological netwo
academic.oup.com
🔴 Stay tuned‼️ The second call of our VIDA Postdoctoral COFUND Programme opens on Monday 🔜 Funded by a Marie Skłodowska-Curie Actions COFUND Grant, #VHIOVIDAEU is recruiting 8️⃣ postdocs. 👉 https://linke.to/VHIOVIDAprogramme25 #VHIOVIDA #TranslationalResearch #VHIOAcademy @ec.europa.eu @cerca.cat
I'd say this is a great guide for detecting LLM-generated text anywhere, not just Wikipedia. ⬇️
Wikipedia editors trying to fend off the onslaught of AI crap have crowdsourced some telltale signs of LLM-generated writing; it might be handy for editors and proofreaders generally. Thanks to @ellenrykers.com for pointing me to it. en.wikipedia.org/wiki/Wikiped...
I've recently started compiling a list of data science related resources that I use or recommend frequently! 📊 Link: nrennie.rbind.io/data-science... #RStats #Python #DataViz #DataScience
We are hiring! We are searching for a motivated bioinformatics scientist interested in joining our team! Apply below: jobs.vhio.net/jobs/6203915...
2025-040-01 Bioinformatics Scientist - VHIO
Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.
jobs.vhio.net