New research now out in Nature Cell Biology, led by Nathaniel F. Henneman in Ganna Panasyuk team, shows that nuclear class 3 PI3K co-activates fasting-specific chromatin remodelling. Read the article here: tinyurl.com/4h4vybsb Learn more about it and about the first author: tinyurl.com/2pdbjdk7

Congratulations to @marco-pontoglio.bsky.social, Julien Diana, @delevoyecedric.bsky.social, Pierre Isnard, @auroreclaudetaupin.bsky.social, Anne Jamet, @esegura-lab.bsky.social, @aminetoubal.bsky.social, Nicolas Venteclef, Jean-François Gauthier, Laurence Arbibe and @mario-pende.bsky.social!

🧪 New publication from the @fabiolaterzi.bsky.social team with @olivieraubert.bsky.social and @danyanglicheau.bsky.social at INEM on how "Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients"

American Journal of Transplantation@amjtransplant.bsky.social · 7d ago

Check out, "Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients," by Aubert et al featured in our July issue. tinyurl.com/5n7brm7k #KidneyTransplant #TransplantImmunology #PostTransplantCare #InfectiousDiseases

🔬 Don't miss out the new publication in @jcellsci.bsky.social from the MEMBRANICs lab at INEM!

MOREL Lab / MEMBRAMICS research@membramics-lab.bsky.social · last wk.

Vimentin intermediate filaments support autophagosome biogenesis at ER–endosome contact sites in response to starvation journals.biologists.com/jcs/article-... check out our last @membramics-lab.bsky.social publication by @frengerquentin.bsky.social on the role of vimentin in autophagy

🔬 How do ADPKD cysts form? A JCI study by @hkd-l.bsky.social at Institut Imagine & Frank Bienaimé's group @inem-necker.bsky.social shows: without polycystin-1, the tubule sleeve gets softer, not stiffer. This loosening lets the tube expand. A new therapeutic target! 👏 📄 jci.org/articles/vie...

📅 SAVE THE DATE | 2026 INEM Prestige Lecture Series From 1 to 4 December 2026, INEM will welcome Professor Fiona Watt, @embo.org Director and an internationally recognised leader in stem cell biology. 📍 INEM : 160 rue de Vaugirard, 75015 Paris More details on our website: tinyurl.com/kp2z4ybv

👏 A huge congratulations to Guillaume Canaud on being awarded the 2026 Mendel Medal, an award recognising his significant work on rare diseases linked to mutations in the PIK3CA gene and on the development of innovative treatments for patients! @eshg.bsky.social

New research now out in Cell Death & Disease from @natureportfolio.nature.com, led by Véronique Baud in @mario-pende.bsky.social team, shows that the alternative NF-kB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development.

New research now out in Cellular & Molecular Biology Letters, led by Edouard Le Guillou in Ganna Panasyuk team, shows that restoration of lysosomal membrane integrity in cell models of Pompe disease depends on fatty acid synthase and its product palmitic acid. tinyurl.com/ytu86hj9

New research now out in @jci.org, led by Manal Mazloum in @fabiolaterzi.bsky.social team, shows that cilia to basement membrane signalling is a biomechanical driver in models of autosomal dominant polycystic kidney disease tinyurl.com/5ahn88ns

📢 INEM Friday Seminar Series At INEM Auditorium 2 Today, Zayna Chaker from the Institute of Functional Genomics of Lyon will present her work at the INEM seminar series "The puzzle of adult brain stem cell coordination: A functional and evolutionary perspective" Details here➡️ tinyurl.com/5xmnjkpn

🧫 Wrapping up today's fantastic MAGIC seminar is @manusingh.bsky.social (@inem-necker.bsky.social). His talk: "Single-Cell Mapping of the Reawakening of Ancient Foes in Ageing Disorders." A deep dive into the molecular & cellular mechanisms of Alzheimer. Thanks to all speakers & see you next week! 🧪

📢 INEM Friday Seminar Series At INEM - Auditorium 3 Today, Marat Yusupov, from IGBMC, Strasbourg, France, will present his work at the INEM seminar series "Study of ribosome structure for the development of drugs" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4474

📢 INEM Friday Seminar Series Today, Robert E. Schwartz, from Weill Cornell Medical College, New York, USA, will present his work at the INEM seminar series "Vascular Identity, Stromal Diversity, and the Challenge of Building a Bioartificial Liver" Details here ➡️ tinyurl.com/szfbjmdc

Retour sur la retraite de l'INEM de ces 2 derniers jours près de Fontainebleau Les membres de l'INEM se sont réunis pour des conférences scientifiques… et vulgarisées 🎤 et pour des activités ludiques🎉 👏 Bravo aux présentateur·ices Et merci aux organisateur·rices et sponsors pour cet événement !

Le 6 mars 2026, Fabiola Terzi, directrice de l’Institut Necker Enfants Malades, a reçu la Légion d'honneur des mains de Gérard Friedlander. Une reconnaissance qui honore un parcours et les valeurs d’ouverture portées par l’INEM. Plus d'information sur le site de l'INEM : tinyurl.com/3ssxkc2b

Aujourd'hui vendredi 13 mars, l'invité du Friday Seminar à l'INEM était Aude Bernheim, chercheuse de l'Institut Pasteur. Invitée par la cellule égalité professionnelle de l'INEM, son séminaire s'intitulait "Ce que le féminisme fait découvrir à la biologie" Plus d'info ici : tinyurl.com/55jmhnh6

📢 INEM Friday Seminar Series 📅 March 6th 📍 INEM Auditorium 3 Today, Mercedes Ricote, from the Centro Nacional de Biotecnología of Madrid, will present the INEM seminar series "Mother´s milk drives maturation of heart metabolism" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4444

📢 Paris Postdocs Seminar 📅 March 5th 📍 INEM Room 4 (-1) Next week, Alexandre Pierga from @institutimagine.bsky.social will present the @parispostdocs.bsky.social "Loss of MTPAP disrupts mtRNA processing causing upregulation of type I interferon signaling" ➡️ tinyurl.com/4stwnnu7

📢 INEM Friday Seminar Series 📅 February 27th 📍 INEM Auditorium 3 Today, Gioacchino Natoli from the European Institute of Oncology, Milan will present for the INEM seminar series "Control of genic and extragenic transcription in inflammation and cancer" Details here ➡️https://tinyurl.com/3pfa6u29

📢 INEM Friday Seminar Series 📅 February 20th 📍 INEM Auditorium 3 Tomorrow, Vassili SOUMELIS from Inserm U976 HIPI will present for the INEM seminar series "Multi-Omic data for patient stratification and personalized medicine in immuno-inflammatory diseases" Details here ➡️ tinyurl.com/jezjvcab

📢 Paris Postdoc Seminar 📅 February 19th 📍 INEM Room 4 (-1) Tomorrow, Hugo Barreto from @institutcochin.bsky.social will present the @parispostdocs.bsky.social "Eco-evolutionary dynamics of bacterial strains across Human gut microbiotas" ➡️ tinyurl.com/5p82htud

📢 Journée des Fournisseurs/Supplier's Day 📅 February 17th 📍 Institut Necker Enfants Malades Next week, INEM is hosting its Supplier's Day ! Over 20 suppliers available to meet with Necker campus researchers & collaborators all day 👩‍🔬👨‍🔬 Organised by the HappyNEM association ➡️ tinyurl.com/mpekc5tb

📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Next week, Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B

Upcoming seminar by Hugo Barreto: If you are interested in meeting with the speaker, please reach at Institut Necker Enfants Malades, Thursday 19 February 2026 at 10:00. More info

[PUBLICATION] The @goffinlab.bsky.social lab shows a promising therapeutic strategy to mitigate prostate cancer progression towards CRPC — now out in EMBO Molecular Medicine @embomolmed.org 👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo 🔗 link.springer.com/article/10.1...

Targeting pre-existing club-like cells in prostate cancer potentiates androgen deprivation therapy - EMBO Molecular Medicine

A critical knowledge gap in prostate cancer research is understanding whether castration-tolerant progenitor-like cells that reside in treatment-naïve tumors play a direct role in therapy resistance a...

link.springer.com

Goffin Vincent Lab@goffinlab.bsky.social · 6mo ago

Pleased to share our recent open access publication in #EMBO Molecular Medicine showing that early eradication of #castration-tolerant #Club cells presents a promising therapeutic strategy to mitigate #prostatecancer progression towards #CRPC 👇 link.springer.com/article/10.1...

📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B

[SEMINAR] 🗓️ Join us today, for a #seminar with Henri-Francois RENARD, group leader at Université de Namur. Pr. RENARD will explore the molecular mechanisms of clathrin-independent endocytosis. Don’t miss it! Invited by @membramics-lab.bsky.social

[PUBLICATION] The Coureuil lab shows how MDA phages promote N. meningitidis colonisation by pili variants selection — out in @natcomms.nature.com 👏🏼 First & last authors: Clémence Mouville & Emmanuelle Bille 🔗 nature.com/articles/s41467-025-67441-w 📰 Read more on INEM website: tinyurl.com/mr3j39xr

Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants - Nature Communications

In Neisseria meningitidis, the filamentous phage MDA is associated with biofilm formation during epithelium colonisation. Here, the authors investigate the relationship between phage MDA infection and...

nature.com

[SEMINAR] 📢 Paris Postdoc Seminar at INEM on Thursday January 22 Maria Lizarralde-Iragorri from @institutimagine.bsky.social will present the @parispostdocs.bsky.social seminar "Investigating Hematopoiesis and Erythropoiesis in Sickle Cell Disease" More info ➡️ tinyurl.com/ykjnp873