Great collaboration and great outcome! Thank you all for this fantastic team effort 🥳👏 @univbordeaux.bsky.social @cnrs.fr @iecb.bsky.social @foldnetuk.bsky.social

Francoise Ochsenbein@francoizochsenbein.bsky.social · 2mo ago

Excited to share our new VIP in Angewandte Chemie! Can foldamers mimic extended protein surfaces? Our peptide-oligourea foldamers reproduce the histone H3-H4 interface on the histone chaperone ASF1, combining nanomolar affinity, stability & cell permeability. onlinelibrary.wiley.com/doi/10.1002/...

Registration is OPEN and abstract submissions are WELCOME 🤓 !!! Our student-led Young Scientist Symposium will take place on the 4th & 5th of June this summer! Olalla Vázquez, Marion Jasnin and Alexandre M.J.J. Bonvin are invited speakers. Visit our website: yss2026.sciencesconf.org

Save the date 🤩🤩🤩! Our student-led Young Scientist Symposium will take place on the 4th & 5th of June this summer! More information and registration available soon!

@iecb.bsky.social fête la science. Atelier fluorescence, cryo-microcopie électronique et extraction d’ADN par des membres de notre équipe.

Join us next Thursday, November 13th, at the IECB amphitheater for our annual Chemistry & Biology Interface Day covering the hottest research topics at our beautiful Nouvelle Aquitaine Region 🤩 🧪 ⚗️ 🧫 🦠 🔬 🤓 !!! Special guest: Dr Priya Ramakrishna @priyaramakrishna.bsky.social from the EPFL Lausanne

Join us tomorrow, Wed 09/24, for our annual 'Looking to the Future' workshop where brilliant researchers form across the globe and IECB faculty candidates will present their outstanding work 🤩🤓!!! Where: IECB amphitheater, Uni of Bordeaux campus When: Wed, Sept 24th, 1:30 pm

👏👏👏

Guichard-Lab@guichard-lab.bsky.social · last yr.

Congrats @radha-tomar.bsky.social for winning the poster prize at the International Symposium on #foldamers 2025 🎉👏 Huge thanks to @andrecobb.bsky.social for organizing such an inspiring meeting at King’s College London! Great science & good vibes! @foldnetuk.bsky.social @iecb.bsky.social

Join us next week for our annual 'Looking to the Future' workshop where brilliant researchers form across the globe and IECB faculty candidates will present their outstanding work 🤩🤩🤩!!! Where: IECB amphitheater, University of Bordeaux campus When: Wednesday, September 24th, 1:30 - 8:30 pm

🚨 Fully funded PhD position in plant & structural biology! Join the @eliastahl.bsky.social lab in collaboration with our team. Exciting project on protein structure/function in plants 🌱. Contact us for details! #PlantBiology #StructuralBiology #PhDposition @iecb.bsky.social

Elia Stahl@eliastahl.bsky.social · last yr.

We are recruiting! A three year PhD position @iecb.bsky.social and @lbm-bordeaux.bsky.social to study lipid recognition by plant receptor-like kinases. A collaborative project with the team of @pierre-maisonneuve.bsky.social. Join us in the beautiful city of Bordeaux! emploi.cnrs.fr/Offres/Docto...

Looking forward to the demo of the @abberior.rocks #MINFLUX in few weeks in Bordeaux (organised by @iins-bordeaux.bsky.social and hosted by @iecb.bsky.social)

L’Institut européen de chimie et biologie @iecb.bsky.social est renforcé par l’acquisition de deux nouveaux microscopes de pointe, offrant aux chercheurs une capacité unique pour explorer l’architecture moléculaire et cellulaire avec une précision inédite : www.u-bordeaux.fr/ac...

Deux nouveaux microscopes pour aller au cœur du vivant

La plateforme de cryo-microscopie électronique à l’Institut européen de chimie et biologie (IECB) est renforcée par l’acquisition de deux nouveaux microscopes, Glacios 2 et Talos L120. Ces équipements de pointe offrent aux chercheurs une capacité unique pour explorer l’architecture moléculaire et cellulaire avec une précision inédite, positionnant Bordeaux comme un acteur majeur dans ce domaine en France.

u-bordeaux.fr

Indeed, we are looking of a PhD student at the interface between chemistry, biophysics and biology to work on light induced LLPS. join us at @iecb.bsky.social in Bordeaux !

JCB@baretjc.bsky.social · last yr.

My colleagues Nicolas Martin (CRPP) and @fichoulab.bsky.social (CBMN) have an open PhD position in Bordeaux ! Light and Liquid Liquid Phase Separation @bxfrontiers.bsky.social

We are recruiting! A three year PhD position @iecb.bsky.social and @lbm-bordeaux.bsky.social to study lipid recognition by plant receptor-like kinases. A collaborative project with the team of @pierre-maisonneuve.bsky.social. Join us in the beautiful city of Bordeaux! emploi.cnrs.fr/Offres/Docto...

Only one week left to apply 🤓!!!

IECB Bordeaux@iecb.bsky.social · last yr.

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!

🎉 New paper out in Science! In collaboration with Marc Therrien’s lab, we show how oncogenic BRAF mutants adopt a pre-active conformation, escaping auto-inhibition and driving RAS–ERK pathway activation in cancer. Proud to have contributed! #IRIC #CBMN @iecb.bsky.social @univbordeaux.bsky.social

BRAF oncogenic mutants evade autoinhibition through a common mechanism

Uncontrolled activation of the rat sarcoma (RAS)–extracellular signal–regulated kinase (ERK) pathway drives tumor growth, often because of oncogenic BRAF mutations. BRAF regulation, involving monomeri...

science.org

Only two weeks left to submit your application!!!

IECB Bordeaux@iecb.bsky.social · last yr.

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!

Fellow ladies in science, as part of the disappearing species of international female scientists in France and perhaps every/elsewhere, I want to bring your special attention to our institute's open call for group leaders 👩‍🔬🦠🧪🔬🤓!!! Come join me in doing some coolicious science here 🙏!

IECB Bordeaux@iecb.bsky.social · last yr.

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!

Check out the latest study from our Campagne Lab on the structure and calcium-dependent activation of the ubiquitous ribonuclease EndoU 🤩! Congratulations to all the authors 👏👏👏 www.nature.com/articles/s41...

Molecular basis for the calcium-dependent activation of the ribonuclease EndoU - Nature Communications

Eucaryotic EndoU are endoribonucleases that require calcium ions to cleave RNA substrates. Here, the authors solved the structure of calcium-activated human EndoU and proposed a structural model for U...

nature.com

🦠 Most #bacteria form #biofilms, protective communities that resist #antibiotics. Petya Krasteva's research explores the structure & behaviour of these biofilms, hoping to develop new #antimicrobial strategies. Read more 👉 buff.ly/YajqauG @krastevalab.bsky.social @iecb.bsky.social @CNRS.fr

Deciphering the formation of cooperative multicellular biofilms

Bacterial films are a hazard throughout the healthcare system, and as antibiotic resistance increases there is an even greater imperative...

buff.ly

Excited to join 2025 Korean Chemical Society 135th General Meeting &Exhibition this week! Always a pleasure to catch up with colleagues and reconnect with lab alumni. Thank you, Sung Hyun @yoo-bios-lab.bsky.social for the fantastic welcome in Korea — truly appreciated! @iecb.bsky.social #ChemSky

We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!

Join us this Friday, April 4th, for an afternoon minisymposium on protein structure and dynamics in disease! The place is as usual our IECB amphitheater!

Check out the latest work from our Guichard Lab creating cell-permeable, macrocyclic peptide-oligourea foldamers to target hDM2 and restore p53 signaling in cancer cells 🤩🧪⚗️!

Guichard-Lab@guichard-lab.bsky.social · 2y ago

See our latest work on stapled peptide-foldamer hybrids targeting hDM2, using cis-4-mercaptoproline for an optimal macrocyclization. 🚀 @iecb.bsky.social @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social #ChemBio #ChemSky Read more: doi.org/10.1002/chem...

Our work on indirect 15N chitin detection in whole cells by Solid-State #NMR with Laurence Delhaes, work done at @iecb.bsky.social with @cnrs.fr and @univbordeaux.bsky.social www.sciencedirect.com/science/arti...

Solid-state NMR Observation of Chitin in Whole Cells by Indirect 15N Detection with NC, NCC, CNC and CNCC polarization transfers

Chitin is the most important nitrogen-containing polysaccharide found on Earth. This polysaccharide is a polymer of an N-acetylglucosamine and it is a…

sciencedirect.com

It was really good to host the French EPR society meeting in Bordeaux at @iecb.bsky.social

Check our study in press in JACS on the use of solid-state #NMR to investigate polysaccharides in encapsulated pathogens, demonstrated on #Cryptococcus neoformans. Congrats to Alons Lends and all coworkers @iecb.bsky.social @cnrs.fr @univbordeaux.bsky.social pubs.acs.org/doi/10.1021/...

Molecular Distinction of Cell Wall and Capsular Polysaccharides in Encapsulated Pathogens by In Situ Magic-Angle Spinning NMR Techniques

Pathogenic fungal and bacterial cells are enveloped within a cell wall, a molecular barrier at their cell surface, and a critical architecture that constantly evolves during pathogenesis. Understandin...

pubs.acs.org

It was such a pleasure and privilege to have Prof Sabine Flitsch from Manchester university presenting today at our IECB seminar series @iecb.bsky.social @univbordeaux.bsky.social @departementsts.bsky.social

Don't forget to join us today!

IECB Bordeaux@iecb.bsky.social · 2y ago

Join us next week on Friday the 7th, at 11 am, in our IECB amphitheater to learn a whole lot on the design and applications of enzyme cascades for organic synthesis 🤓🧪👩‍🔬⚗️! Guest speaker Prof. Sabine Flitsch from the University of Manchester 🤩!!! www.iecb.u-bordeaux.fr/evenements/i...

Happy to share our work on guanidinium-stapled peptides, now published in @angewandtechemie.bsky.social! A versatile method to stabilize peptide helices for precise protein surface recognition. Congrats to the team and special thanks to Morgane Pasco! 👏 🔗 doi.org/10.1002/anie... @iecb.bsky.social