Very happy to celebrate the first paper from the Nilsson-Payant Lab @ki.se! We investigated inactivation methods for hantaviruses (including ANDV) and for how long they can remain infectious in the environment under different conditions! journals.plos.org/plosntds/art...

Hantavirus stability and inactivation

Author summary Hantaviruses are ubiquitous rodent viruses and contain some of the most lethal known zoonotic viruses, including Andes virus (ANDV) and Hantaan virus (HTNV), with no FDA- or EMA-approve...

journals.plos.org

We are recruiting a lab manager for my group in Oxford. This is a lovely team doing great things, and you could be an important part of it! See here: www.path.ox.ac.uk/vacancy/lab-... Please spread the word!

Lab Manager - Molecular Immunology - Dunn School

Laboratory Manager/Senior Scientist position in the Molecular Mucosal Immunology group at Oxford

path.ox.ac.uk

Very happy to see our book "Trigger Points" finally out in English, and fully open access! Hopefully a useful resource for anyone working on polarization, class, inequality, migration, diversity, and climate change.

The Max Planck Institute for Political and Social Science@mpips.bsky.social · 3mo ago

Why do our societies seem so deeply divided when most citizens actually occupy a broad political middle ground? @steffenmau.bsky.social, @thomaslux.bsky.social & @lwestheuser.bsky.social unpack this paradox in Trigger Points, pub. today @brisunipress.bsky.social, Foreward @mikesavagelse.bsky.social

Super happy to see the final version of our paper out now 🎉🎉🎉 www.science.org/doi/10.1126/... Proud of PhD student Rupesh @rupeshjayachandran.bsky.social and postdoc Erwan for doing really nice work on this 😊

Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access

Henipavirus nucleoprotein assemblies exist in different conformations, indicating temporary release of genome for RNA synthesis.

science.org

Max Renner@maxrenner.bsky.social · 11mo ago

Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇

Our paper is finally out! 🥳 If you want to know how a single Salmonella effector rewires the whole macrophage transcriptional landscape by hijacking one host transcription factor, check our latest research! Thanks to the @thurstonlab.bsky.social and @peterwshill.bsky.social labs for an amazing work!

Salmonella effector SteE reprograms the macrophage regulatory network to drive specific hyperactivation of STAT3 target genes

The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication, and dissemination is central to its pathogenesis. T…

sciencedirect.com

Do you live in Oxfordshire? Join us for our 1st Workshop on what our future streets could look like. 📅When: 24 March 6.30-8.30pm 💻Where: Zoom 🤔Why: Be part of creating a new vision for our urban spaces Book now: Eventbrite: shorturl.at/PRAzT #FutureStreetsOxfordshire

OK, this is wild. In September 2023, geophysicists across the world started monitoring a very odd signal coming from the ground under them. It was picked up in the Arctic. And Antarctica. It was detected everywhere, every 90 seconds, as regular as a metronome, for *nine days*. What the HELL? 1/

In terms of what cures are being lost: - Epstein-Barr virus is perhaps the major trigger for multiple sclerosis - herpes simplex virus causes cold sores, genital herpes, infections in babies, deadly meningitis - shingles virus causes an intensely painful disease

I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵

As if Nipah virus weren’t bad enough, some patients in Asia were coinfected with an emerging bat virus called Pteropine orthoreovirus (PRV). Symptoms of PRV include fever, disorientation, abnormal gait, and difficulty breathing. PRV seems to have traits that increase likelihood of zoonosis.

Emerging bat virus found in stored throat swabs from 5 patients with suspected Nipah virus infection

cidrap.umn.edu

I'm seeing relatively little chatter or outcry about what is happening at the MRC, the UK's biomedical research funder. Before Christmas MRC paused the acceptance of many of its grants, including the standard applicant-led research grant. There has been no public information on what is happening 🧵

Beautiful work from @efodor.bsky.social and Jonathan Grimes' labs - the first full structure of the influenza A virus NEP protein, and a clear indication that its role in viral replication is more nuanced that first thought www.science.org/doi/10.1126/...

Regulatory hotspot on the influenza A virus polymerase revealed through the structure of the NEP-polymerase complex

Structural studies reveal how influenza virus switches between making new RNA genomes and exporting them from the host nucleus.

science.org

Researchers from across Oxford University were on the ground at #COP30 in Belém, taking part in side events, presenting new research, and working with partners to support the negotiations and inform the wider political process. Read on for perspectives from Oxford experts ⬇️

Expert Comment: Reflections on COP30 in Belém | University of Oxford

Researchers from across the University of Oxford were on the ground at COP30 in Belém, taking part in side events, presenting new research, and working with partners to support the negotiations and

ox.ac.uk

allafrica.com/stories/2025...

Namibia Confirms Outbreak of Deadly Congo Fever

Minister of health and social services Esperance Luvindao has confirmed an outbreak of the deadly Crimean-Congo haemorrhagic fever (CCHF) in Namibia, for which no vaccine or specific treatment exists.

allafrica.com

From mosquitoes carrying dengue and chikungunya in Indian Ocean islands to West Nile virus now endemic in parts of Europe, climate change is redrawing the global map of infectious disease. Mail & Guardian coverage our COP30 Report - mg.co.za/the-green-gu...

Climate change is spreading dengue, chikungunya and West Nile virus worldwide

A new COP30 report finds that rising temperatures, extreme weather, evolving pathogens and climate-driven migration are reshaping disease patterns

mg.co.za

Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇

I'd love to say lots of nice things about this invaluable preventable disease tracker from @monscience.bsky.social and team at Think Global Health. It's an incredible resource. But I can't get over my anger & sadness that this resource is even needed. www.thinkglobalhealth.org/article/vacc...

Vaccine-Preventable Disease: A Global Tracker | Think Global Health

This map is updated weekly and visualizes outbreaks of nine childhood diseases in collaboration with the International Society for Infectious Diseases

thinkglobalhealth.org

warwick.ac.uk/fac/cross_fa... I am advertising for a PhD position in my group. We'll be investigating how pathogenic RNA viruses replicate in the nucleus. The project will teach cryoEM/ET, virus culture, and in vitro assays. If you're interested reach out and I'd be happy to have a chat.

Mysteries of trafficking of the vRNP segmented genome and assembly of influenza A virus revealed by in situ cryo-ET! 🔗 rdcu.be/eMmct We are very excited that our paper is finally out! 🎉 Big congratulations to Moritz Wachsmuth-Melm and to everyone involved.

www.biorxiv.org/content/10.1... Really excited to have our work out in the world. CCHFV has a 450kDa L-Protein, about twice the size of L-Proteins from other segmented RNA viruses. We have used cryoEM and functional assays to begin to understand it this massive multifunctional protein works.

Structural and functional characterisation of the Crimean-Congo Haemorrhagic Fever Virus RNA Dependent RNA Polymerase

Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is found across Africa, Asia, and the Middle East where it can cause Haemorrhagic outbreaks with high case fatality rates. Central to the viral life cycl...

biorxiv.org

Structural and functional characterisation of the Crimean-Congo Haemorrhagic Fever Virus RNA Dependent RNA Polymerase www.biorxiv.org/content/10.1101/2025.10.21.683639v1 #cryoEM

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

Jane Goodall was my first childhood hero, as I loved animals as a kid and was inspired by her story. I still remember the National Geographic specials about her. RIP.

www.nature.com/articles/d41...

Dozens of heatwaves linked to carbon emissions from specific companies

Nearly one-quarter of heatwaves would have been ‘virtually impossible’ without global warming — and can be attributed to the emissions of individual energy producers.

nature.com

Very pleased to have our new work out where we perform a structure/function study on the bornavirus polymerase complex with fantastic coauthors. Have a read www.nature.com/articles/s41... @warwicklifesci.bsky.social @loiccarrique.bsky.social @franziskaguenl.bsky.social

The structure of the mammalian bornavirus polymerase complex - Nature Communications

Borna disease virus 1 replicates and transcribes its negative sense RNA genome in the nucleus of infected cells. Here, the authors present the cryoEM structures of the large polymerase protein in comp...

nature.com

How can we handle lab waste more sustainably? Saroj Saurya (@dunngogreen.bsky.social) and colleagues just published this interesting new piece! Have a read! 🌿 academic.oup.com/genetics/adv...

Toward more sustainable research: reducing the environmental impact when working with Drosophila

Abstract. The ever-increasing amounts of plastic waste and greenhouse gas emissions worldwide threaten our environment. Biomedical laboratories across the

academic.oup.com

🆕 Study evaluates three vaccine candidates for one of the world’s most dangerous viruses, the Nipah virus. An international team of scientists led by The Pirbright Institute achieves a breakthrough in controlling a deadly virus with pandemic potential ⬇️ #Zoonoses #Zoonotic #OneHealth

New study brings vaccine hopes for deadly Nipah virus

Scientists at The Pirbright Institute have taken a major step forward in tackling one of the world’s most dangerous viruses, the

pirbright.ac.uk

Half way through the decade of action for road safety, and I can't say I feel massively safe cycling on Oxford's streets. Maybe #worldbicycleday should be introduced here to raise awareness and direct our collective energy towards increasing the safety of non-motorized traffic?

WHO@who.int · last yr.

Today is #WorldBicycleDay 🚲 Did you know❓ Cycle lanes count for just 0.2% of the current road infrastructure. It’s time to demand safer streets that put the health & safety of pedestrians and cyclists first 👉bit.ly/4jPzXsa

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. www.science.org/doi/10.1126/...

Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis

Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...

science.org