Margherita Colucci

@margheritac17.bsky.social

Forensic and Pop.Genetics🧬Human and disease coevolution🧬genetic genealogy🧬Evolutionary Ecology @HumanPalaeosystemsResearch group @MPI-GEA & @EGG_Cam

New preprint! "Joint dog and wolf genealogies reveal the evolution of the canine genome" We build genealogies of dogs and wolves to find two strong mutation-rate pulses, GC-biased gene conversion, selection, and inter-species gene flow shaping the canine genome. www.biorxiv.org/content/10.6...

Joint dog and wolf genealogies reveal the evolution of the canine genome

Dogs and their closest extant relative, the grey wolf, diverged around 30k years ago, but have since experienced complex histories of gene flow involving other canids, adaptive pressures due to close ...

biorxiv.org

I've decided to do a Bluesky run-through of my Animal Kingdom book: 100 more posts about the inner workings of natural history, biodiversity and evolution, told through 100 museum objects. A couple per day, starting… now! 🧵 www.thehistorypress.co.uk/publication/...

Animal Kingdom

From a single beginning, countless millions of stories from the animal kingdom have – and continue to – run their course. Museum objects allow us to investigate some of those stories. Animal Kingdom j...

thehistorypress.co.uk

🦟Infectious disease has shaped the deep history of our species, as new research co-authored by members of our Evolutionary Ecology Group reveals. @eegcam.bsky.social @mikleonardi.bsky.social @ceciliapad.bsky.social www.science.org/doi/10.1126/...

University of Cambridge@cam.ac.uk · 3mo ago

Malaria was fundamental in shaping the course of human evolution, @camzoology.bsky.social researchers have found. Between 74,000 and 5,000 years ago, early humans in Africa avoided high-risk malaria areas, shaping the population structure seen today. Read more 👉 https://bit.ly/4tUdOxe

A serene natural landscape featuring a reflective water body with lily pads, surrounded by lush greenery and distant trees. The foreground shows a small grassy bank. Text overlay reads " New Cambridge research: Malaria shaped the distribution of early humans across Africa."

1/5 Well over three years of work and I’m thrilled to see it out today in Science Advances: the cover feature no less! Using an innovative pipeline, we show that malaria shaped the spatial organization of human groups in sub-Saharan Africa over the last 74,000 years. www.science.org/doi/10.1126/...

Malaria shaped human spatial organization for the past 74 thousand years

Malaria has shaped human habitat choice, exchange, and dispersal since the late Pleistocene in sub-Saharan Africa.

science.org

News in the history of molecular biology. The Science History Institute in Philadelphia has acquired a huge archive of correspondence and other scientific material from the pioneers of molecular biology (Franklin, Klug, Perutz, Delbrück etc, with items from Crick and Watson, too). 1/n

History of Molecular Biology Collection

This unparalleled collection includes Rosalind Franklin's historic 'Photo 51,' which revealed the double-helix structure of DNA.

sciencehistory.org

New paper in collaboration with @lucytimbrell96.bsky.social and @jblinkhorn.bsky.social, with several of us involved (@mikleonardi.bsky.social @margheritac17.bsky.social @andreavpozzi.bsky.social) shows that downscaling palaeoclimate models doesn't necessarily improve coherence with proxy data.

Lucy Timbrell@lucytimbrell96.bsky.social · last yr.

Very pleased to see our paper published online at Climate of the Past: cp.copernicus.org/articles/21/... We present model-data comparisons of Late Quaternary climate across the Northern Hemisphere, showing that increasing model resolution has little net effect on coherence with pollen proxies 😊

1/5 Why do all non-Africans descended from a group that left Africa 50k ago? In @nature.com we model 120k years of human niche dynamics. From 70ka, a big expansion of the human niche in Africa likely equipped later OOA dispersals with a unique ecological flexibilty. www.nature.com/articles/s41...

Major expansion in the human niche preceded out of Africa dispersal - Nature

Analysis of species distribution models in a pan-African database comprising chronometrically dated archaeological sites over the past 120,000 years shows major expansion in the human niche from 70 ka...

nature.com