It is finally out! Updated with exciting in-vivo microtubule disruption results to protect Lmna deficient nuclei from damage. My final postdoc project with Prosser Lab and a great collaboration with @lammerdinglab.bsky.social, Shenoy Lab, and Jain lab.

Nature Cardiovascular Research@natcardiovascres.nature.com · 9mo ago

Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target. doi.org/10.1038/s441... rdcu.be/eOeTA

Quantifying cardiomyocyte contraction & nuclear deformation interaction reveals nucleus-damaging mechanism underlying LMNA cardiomyopathy 📷 @apdaria.bsky.social & Julie Heffler et al @weillcornell.bsky.social @pennmedicine.bsky.social in @natcardiovascres.nature.com ➡️ bpod.org.uk/archive/2025...

Join us for the first Mechanobiology of the Nucleus conference supported by @faseborg.bsky.social. Co-organized with @lammerdinglab.bsky.social, @katemiro.bsky.social and Verena Ruprecht, the amazing program is here: events.faseb.org/event/Mechan... Opportunities for talks! Abstracts by Aug. 31st.