Our 3rd #StemGastro conference is just around the corner, and is set to be our biggest series yet. Full of networking, collaboration & the latest research, dont miss out! There's still time to join us this November➡️ bit.ly/4y64skB
Kate Miroshnikova
@katemiro.bsky.social
Bioengineer interested in #mechanobiology of cell state regulation, cancer, genome integrity, #chromatin & nuclear mechanics
#Mechanobiology rules! Today, it's not only Chile's independence day🇨🇱😋 ...but also Sara Wickström @sarawickstrom.bsky.social is getting the Körber Prize 👏🏽👏🏽👏🏽 for being a "curiosity's junkie" 😂 Of note, Kate photobombing is top @katemiro.bsky.social @focalplane.bsky.social @koerber-ip.bsky.social
Great speakers, great science, great location = great meeting! EMBO workshop Forces across scale April 27-30, 2027 in Porto. meetings.embo.org/event/27-for...
Forces across scales
This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…
meetings.embo.org
Turns out the way DNA is packed inside the nucleus can tune the mechanics of the entire cell! Super excited that our first paper is out in Nature Communications! www.nature.com/articles/s41... !
Chromatin decompaction within the nucleus increases plasma membrane tension promoting NETosis execution, independently of transcription - Nature Communications
Chromatin organizes nuclear DNA, but whether it actively regulates whole-cell mechanics remains unknown. Here, we used NETosis to show that chromatin decompaction within the nucleus increases plasma membrane tension and cell volume, establishing chromatin as a regulator of cell mechanics.
nature.com
Congratulations, @jeffreyafarrell.bsky.social, on winning the @socdevbio.bsky.social #2026SDB Elizabeth D. Hay New Investigator Award! Learn more about Jeff's science and career in his @dev-journal.bsky.social interview with @saanjbati.bsky.social.
Transitions in development – an interview with Jeffrey Farrell
Jeffrey Farrell is an Earl Stadtman Investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), USA, where he heads the Unit on Cell Specification and ...
doi.org
🤩🤩🤩It was a pleasure & a lot of fun, as always, to work with @jcellsci.bsky.social on this - congratulations on a fantastic issue all about the #nucleus 😎😎😎
We spoke to Kate @katemiro.bsky.social about her ‘random walk’ into cellular biophysics, how AI might uncover links between nuclear morphodynamics and cell fate hiding in plain sight, and fishing for crayfish as a child growing up in Kazakhstan. journals.biologists.com/jcs/article/...
Our Cell Scientist to Watch interviews in our Cell Biology of the Nucleus Special Issue are with Kate Miroshnikova @katemiro.bsky.social and Andrew Stephens @andrewdstephens.bsky.social. journals.biologists.com/jcs/issue/13...
Thanks for being such a great host @simonereber.bsky.social & looking forward to expanding #biophysics analyses of #chromatin together! 🎉
🌟 Thanks to @katemiro.bsky.social @mpi-muenster.bsky.social for visiting & discussing the mechano-osmotic state of the #nucleus and #chromatin! 🌟
Our Special Issue: Cell Biology of the Nucleus is complete Explore our Toc: journals.biologists.com/jcs/issue/13... Our cover image shows the posteriorly positioned nuclei (Nup50-mCherry - pink) of notochord cells in Ciona embryos. See article by Peng et al. journals.biologists.com/jcs/article/...
Congratulations, Sara on the #KörberPrize 🤩 🤩 🤩 for your pioneering work in #mechanobiology 🎉 🎉 🎉 It has been an honor to be a part of the amazing scientific discovery journey!!! 😎
Huge congratulations to Sara Wickström! 🎉Our director @mpi-muenster.bsky.social has been awarded the #KörberPrize 2026. The scientist discovered that genes respond not only to chemical signals but also to the physical properties of their surroundings. @koerber-stiftung.de @sarawickstrom.bsky.social
Truly honored to recieve this recognition-a testament to the dedication, hard work and creativity of past and current lab members, I am grateful to be able to do science with them. Also want to thank all our wonderful collaborators that facilitate interdisciplinary work essential for new discoveries
🌟 Congratulations to Sara Wickström! 🌟 Our Director Sara Wickström @sarawickstrom.bsky.social receives the Körber Prize for her groundbreaking research on how cells sense physical forces, influencing genes and potentially leading to new disease treatments. s.academiccloud.de/ouQdRQ
bioRxiv alert! CoPhasing resolves haplotype-specific 3D chromatin structures from GAM data, revealing extensive structural heterogeneity between human homologous chromosomes and its interplay with histone modifications and gene expression! Thanks to all coauthors! www.biorxiv.org/content/10.6...
biorxiv.org
The @sfb1348.bsky.social Meeting “Mechanochemical Signals at Cellular Interfaces” is just around the corner! We are excited to welcome an outstanding lineup of international speakers to #Münster for three days of inspiring scientific exchange and discussion. @uni-muenster.de
Very happy to see our work on the cover of @jem.org 🤩
The cover of @jem.org May issue (rupress.org/jem/issue/22...) is a confocal microscopy image of an immunostained mouse fat sample depicting Laminin α4–positive white #adipocytes (gray) & Pecam1-positive blood capillaries (gold). From @petrovalab.bsky.social: doi.org/10.1084/jem....
We´re hiring a #PhD student - if you´re interested in combining genetics, cell biology and state-of-the-art imaging to study #epithelial tissue dynamics in #Drosophila, apply to the CiM-IMPRS PhD program by May 1st (see below) Please RT @uni-muenster.de @sfb1348.bsky.social
Deadline approaching! The CiM-IMPRS #PhD program in #Münster is recruiting: 16 #PhD positions in Life & Natural Sciences. Great chance to do cutting-edge research in a vivid international environment—apply by May 1st: www.uni-muenster.de/CiM-IMPRS/ap... @uni-muenster.de @mpi-muenster.bsky.social
How can we learn tissue mechanics directly from cell patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5
@katemiro.bsky.social we are looking forward to your presentation at the #StemGastro this November.☀️Please share to let your followers know you're speaking & talk submission closes on 07 May 2026! More details: bit.ly/4c0LX8y
@lsprahl.bsky.social and Ronald Canlla in the lab just published a detailed study on remote-controlled epithelial budding morphogenesis. We can direct budding, tubule elongation, and perhaps branching in human kidney organoids via a light-activated RET receptor. www.biorxiv.org/content/10.6...
The CiM-IMPRS PhD program in #Münster is offering 16 #PhD positions in Life and Natural Sciences! Perform cutting-edge resesearch in a vibrant international setting and lively city! Apply by May 1st, 2026 - see www.uni-muenster.de/CiM-IMPRS/ap... @uni-muenster.de @mpi-muenster.bsky.social
We are offering 5 Postdoc Positions within the Max Planck Postdoc Program! Take advantage and apply by April 13, 2026 to the positions in the labs of @ralfhadams.bsky.social, @ruibenedito.bsky.social and @katemiro.bsky.social. Link to our website: www.mpi-muenster.mpg.de/max-planck-p...
Home from a great #EMBO workshop in Barcelona. Intracellular mechanics & organelle Mechanobiology was such a fun topic! @christanny.bsky.social made sure I didn’t get lost. It was great to catch up with @katemiro.bsky.social 1st time in almost 10yrs!!. Thank you to the hosts.. (continued) 1/2
Große Freude! Die @dfg.de richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert den etablierten Verbund @sfb1348.bsky.social. Insgesamt fließen rund 24 Millionen Euro an die Universität Münster.
24 Millionen Euro für zwei Sonderforschungsbereiche
Die Deutsche Forschungsgemeinschaft richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert einen etablierten Verbund zu zellulären Grenzflächen. Insgesamt fließe...
uni-muenster.de
Launching celldynamicslab.com, the homepage of our new group at EPFL working on cell fragmentation, membrane and cortex mechanics, FLIM imaging, and microfluidics tools. MSc/PhD or postdocs interested in quantitative cell biology are welcome to reach out. We're also hiring a lab manager in 2026!
Main - Cell Dynamics and Fragmentation Lab
The Cell Dynamics and Fragmentation lab at We study how single cells move and fragment in complex environments using microfluidics. We bring tools and concep...
celldynamicslab.com
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost! www.keystonesymposia.org/conferences/...
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
keystonesymposia.org
💫NEW: @sarawickstrom.bsky.social @katemiro.bsky.social & co show that mechano-osmotic changes in the #nucleus induce general #transcriptional repression and prime #chromatin for cell fate transitions by relieving repression of specific differentiation genes. #pluripotency bit.ly/3VMcyNZ
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
bit.ly
Amazing to have our work finally out!!! 😍🤩😍
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Amy, Leanne, Maria & Kate welcomed our #SCC25 attendees to the beautiful Malta this afternoon, a great 4 days ahead for this group, discussing all things Stem Cells & Cancer! @joneslabucsf.bsky.social @mariapalcolea.bsky.social @katemiro.bsky.social
Happy to share the latest work from Preeti Sahu, with Adriana Sanchez-Danes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! See 🧵 below (1/n) bit.ly/3ZXxJzk