Jon Marles-Wright

@jmarlesw.bsky.social

Scientist, husband to @lislowe, father. Views my own. He/him.

Our study on Bacteroides iron piracy is now out in @pnas.org. We show how surface-exposed lipoproteins bind xenosiderophores with different iron-chelating chemistries and propose a mechanism for xenosiderophore import across the outer membrane. Lots of structures (mostly X-ray this time)!

Structural basis of iron piracy by human gut Bacteroides | PNAS

Iron is an essential element that can be growth-limiting in microbial communities, particularly those present within host organisms. To acquire iro...

doi.org

We’ve been sciencing! M abscessus makes a arabinanase toxin to chop up the cell wall of competitor mycobacteria! #glycotime 🦠 thanks to @wellcometrust.bsky.social for the funding that makes this collaborative work possible! Also Sam’s structures are 😍 and Jean-Lou did some lovely biochem

Patrick Moynihan@pmoyniha.bsky.social · 4mo ago

We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...

Please join us in the North East on the 5th of November as we celebrate with a one day symposium for the launch of our BBSRC funded 100 keV Tundra TEM aka the Northern Eye: nusbf.ncl.ac.uk/ccpem-tfs-ne... The symposium has been kindly sponsored by @thermofishersci.bsky.social & @ccpem.bsky.social

Grand Opening of the Northern eye, a cryo-TEM in Newcastle

Grand Opening of the Northern Eye in Newcastle, a100 kV Tundra cryo-TEM in Newcastle University on Wednesday 5th November 2025

nusbf.ncl.ac.uk