Join the 9th Austrian CRYO-EM Symposium at Vienna BioCenter on September 24-25! Register before Sep. 1st (Abstract deadline is Aug. 5th!): www.imp.ac.at/research/cry...
TJ McCorvie
@allostericstate.bsky.social
Revealing the hidden world of shape shifting enzymes using Cryo-EM. Senior research associate at Newcastle University, UK. Currently working as part of Recon4IMD https://www.recon4imd.org Views are my own.
Heading to #IUCr2026 in Calgary, 11-18 Aug? At booth #29 we're sharing how we’re bringing more #cryoEM to more spaces. And don't miss our Lunchtime Symposium with an expert panel answering your questions Thu, 13 August, 13:00, Champions C suite. Register: ter.li/9lf78lq5 #StructuralBiology
According to the parliamentary annual report & accounts for the 2025/26 financial year, the cost of subsidising the bars in the House of Commons alone was around £5.8 million. Meanwhile, to save £3 million less than that, Jodrell Bank is being defunded and shut down. share.google/MRHIvCsCsKoc...
Jodrell Bank's Lovell telescope faces axe in science cuts, BBC understands
Astronomers warn it would tear the heart out of UK science, and leave a generation untrained.
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Research Associate (structure and function of large histone deacetylase containing repression complexes) Prof. John Schwabe, University of Leicester - Molecular and Cell Biology, experience of Cryo-EM, NMR and Crystallography www.jobs.ac.uk/job/DSL479/r... #NMRjobs #NMRchat #NMR 🧲
Research Associate at University of Leicester
Explore an exciting academic career as a Research Associate. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
jobs.ac.uk
Closing this weekend! Join us as a scientific biocurator in the OneDep biocuration team. Work with structural data, software and processes that support data deposition and curation. Apply by 2nd Aug: tinyurl.com/47t93kxp. CAK-CDK1-Cyclin-B1: Timing is everything (#cryoEM EMD-54971).
One month left to apply (deadline August 31st)! 👇 #Virology #AcademicJobs #FacultyJobs #FacultyPosition #TenureTrack #GroupLeader
We are looking for an Assistant or Associate Professor to join us at the @utrechtvirology.bsky.social. Interested in building an independent research programme in a collaborative #virology environment? Please take a look and share with anyone who might be a good fit! www.uu.nl/en/organisat...
Pacha's Just Right Meme
ALT: Pacha's Just Right Meme
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Recovery of a minor cryo-EM particle population reveals conformational equilibria linking cofactor loading, turnover, and reactivation in methionine synthase https://www.biorxiv.org/content/10.64898/2026.07.27.741092v1
BRCA2 and RAD54B FxPP motifs Bind DMC1 Filaments through Persistent and Transient Interfaces www.biorxiv.org/content/10.64898/2026.07.24.740592v1 #cryoEM
Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4 pubmed.ncbi.nlm.nih.gov/42497866/ #cryoEM
We are hosting candidates to apply for a PhD position with a full salary at University of Helsinki. This will be a co-supervised project with the group of Alexander Mühleip to study function, structures and draggability of ER protein translocation in different parasitic organisms.
RESDOC Project – Training Doctoral Excellence for Resilient and Just Future | University of Helsinki
RESDOC (Resilient and Just Systems Doctoral Project) is an international doctoral training project at the University of Helsinki in Finland. It brings together interdisciplinary and cross-sectoral res...
helsinki.fi
Happy that our most recent paper on nucleotide excision repair mechanisms has now been published in Science Advances. This project was led by @natalia-mg.bsky.social and @callumhaste.bsky.social and focused on visualising early steps of the NER process by #cryoEM. www.science.org/doi/10.1126/...
Visualization of stepwise derepression of TFIIH in global genome nucleotide excision repair
Cryogenic electron microscopy captures nucleotide excision repair complexes assembling on damaged DNA templates.
science.org
🚀 Can automation solve preferred orientation in your #cryoEM datasets? After automating processing across 21 GPCR datasets in #CryoSPARC, we updated the workflow to be even more robust to preferred orientation, achieving improved map quality over manual processing. Read more 👉 bit.ly/3RyOIGG
Job alert: Viruses (#cryoEM EMD-24741), chaperones, molecular assemblies, enzymes, drug targets and more. Structures tell stories. Join the EMDB and OneDep biocuration team at EMBL-EBI and help scientists tell theirs. Apply by 2nd Aug: tinyurl.com/47t93kxp
We currently have an opening for a PhD position in the lab. If you are interested in pursuing some serious structural biology of photosynthetic and chloroplast processes please apply. Prerequisite is previous experience in cryoEM and/or phototrophs. stellenangebote.uni-marburg.de/jobposting/2...
Doctoral and Postdoctoral Researcher Positions in the Cluster of Excellence ‘Microbes for Climate’
stellenangebote.uni-marburg.de
Today I'm posting a blog about another ridiculous antibody blunder. Dozens of papers in the senescence and ageing field have mistakenly used an antibody for E. coli β-galactosidase when trying to stain for the human protein with the same name. forbetterscience.com/2026/07/21/d...
Job alert: Protein chaperones ensure proteins fold correctly (#cryoEM EMD-23004). Biocurators ensure structural biology data are accurate and reusable. Join the EMDB and OneDep biocurators to maintain the integrity of structural biology data. Apply by 2nd Aug: tinyurl.com/47t93kxp
King’s College London is hiring a Facility Manager to lead their new Cryo-EM Structural Discovery Facility... and more! 🔬🏛️ 🗓 Apply by 23 July 2026: https://f.mtr.cool/icjergnngx #CryoEM #CoreFacilities #ResearchJobs @kingscollegelondon.bsky.social
Cryo-EM Facility Manager | King's College London
f.mtr.cool
Some progression on 58 kDa GBA as part of my work with @recon4imd.bsky.social. Combined tilted data (Glacios) with careful processing gives a ~4.0 Å map with clear secondary structure features. Still not the resolution that I need for variant studies but a step in the right direction! #CryoEM
1/5: Our latest preprint is out! We show that LEA proteins can diversify particle orientations in cryo-EM, helping to overcome preferred orientation at the air-water interface (AWI). www.biorxiv.org/cgi/content/... with @cijilim.bsky.social and Tim Grant #CryoEM #LEAproteins
Diversifying particle-orientation distributions in cryo-EM with LEA protein additives
Preferential orientation at the air-water interface (AWI) remains a persistent challenge in cryo-electron microscopy, often requiring extensive optimization or specialized grid preparation strategies....
biorxiv.org
🚨 FINAL CALL - just 4 days left to apply for an in-person place on the Wellcome–MRC in situ Cryo-ET Workshop 2026. 📅 28 Sept – 02 Oct 2026 📍 @diamondlightsource.bsky.social & @astburycentre.bsky.social 💻 Hybrid stream available ⏰ In-person application deadline 19 July 🔗 shorturl.at/LRihg
looks like Thames Water has given a 14% pay rise to its chief executive and a 26% rise to its finance director
Academic publishing Gen-AI slop of the day (courtesy of a colleague who finds them with Image Search. Hungry now.
Interested in applying cryo-ET and cryo-FIB in your research? Apply for the Wellcome-MRC in situ Cryo-ET Workshop by 19 July for in-person attendance and 25 September for online! 📅 28 September - 02 October 📍 Diamond Light Source, the Astbury Centre and online Learn more 👉 https://bit.ly/4wGL38Z
Great opportunity alert! @dunnschool.bsky.social has opened its annual call for new PIs looking for sponsorship for early career fellowships. If you think we might provide the scientific environment you need to launch your independent career, we want to hear from you!
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...
⏰ 6 days left to apply for an in-person spot on the Wellcome–MRC in situ Cryo-ET Workshop 2026! 📅 28 Sept – 2 Oct '26 🔬 #Cryo-ET & #Cryo-FIB lectures, demos & practicals 📍 @diamondlightsource.bsky.social & @astburycentre.bsky.social 💻 Lectures also available on Zoom Apply now: shorturl.at/LRihg
Wellcome-MRC in situ Cryo-ET Workshop 2026 - - Diamond Light Source
eBIC (Diamond light source) has partnered with the Astbury Biostructure Lab (University of Leeds), the Scottish Centre for Macromolecular Imaging (University of Glasgow), Midlands Regional Cryo-EM Fac...
shorturl.at
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
path.ox.ac.uk
Best “remove glasses to look at something unbelievable” in cinema history.
Jurassic Park: Dr. Grant's Surprise
Alt: Jurassic Park: Dr. Grant's Surprise
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