Maria Sibilia
@maria-sibilia.bsky.social
Scientist & Cancer Researcher, Professor for Tumorbiology, Director of the Center for Cancer Research, Medical University of Vienna & CCC, President of the Senate of the Medical University. #cancer #signaling #tumorimmunology #innate-immunity
✨ Introducing the speakers of our #TumorMicroenvironment sessions at the #FrankfurtCancerConference 2026 – Part 2: ▫️Maria Sibilia @maria-sibilia.bsky.social ▫️Sheila Stewart ▫️Lars Zender ▫️Florian Greten ⏰Register until tomorrow (June 25)! 📆 Sep 2–4, Frankfurt 🔗 www.frankfurtcancerconference.org
Excited to share our new paper! 🔝👇 rdcu.be/fl6UL We uncover an unexpected mechanism underlying the therapeutic effects of anti-EGFR treatment in CRC. Rather than acting through tumor cells, our findings highlight a key role for EGFR signaling in myeloid cells in inducing an immunosuppressive TME.
Don’t miss this interesting event 👇
Elke Ziegler@elkeziegler.bsky.social · 4mo ago"Frauen forschen" Ausgabe Nummer 3 - heute ab 18.30 Uhr im Studio 2 im Radiokulturhaus spreche ich mit @maria-sibilia.bsky.social über den aktuellen Stand der Krebsforschung und ihre Suche nach Antworten auf viele "Warum": radiokulturhaus.orf.at/artikel/7268...
Two fantastic days with great talks and scientific discussions have come to an end. A big thank you to all the SHIELD PhD students for organizing such an fantastic program with an impressive line-up of speakers! 👏👏 @shieldprogram.bsky.social @
📣 Submit your abstract to the Frankfurt Cancer Conference 2026 (Sept 2–4, @goetheuni.bsky.social) for a chance to give a short talk. 📅 Deadline: March 26 www.frankfurtcancerconference.org Looking forward to our keynote speaker Carl June and an excellent lineup! #FrankfurtCancerConference
Our exciting collaboration paper is out 👇and investigates how chronic inflammation in the skin (psoriasis) prevents tumor development. 🔝👏👏Have a look 👀. Thanks for involving us in this important study 🙏🏾 Center for Cancer Research Medizinische Universität Wien www.pnas.org/doi/10.1073/...
Psoriasis-like disease prevents squamous skin tumor development by neutrophil-driven inflammation | PNAS
Psoriasis is a chronic inflammatory skin disease affecting millions of people worldwide. Although growing evidence links chronic inflammation with ...
pnas.org
@josjonkers.bsky.social @olivierpertz.bsky.social @maria-sibilia.bsky.social @lwellberg.bsky.social Please hit repost and help spread the word - Thank you!
Don‘t miss it 🔝
Fusion Conferences@fusionconf.bsky.social · 10mo ago💰ECR grants for #FGF26 now available to help defray the meeting costs for those in junior faculty. Details on how to apply - click here ➡️https://bit.ly/47ivjOf ⌛️Don't forget talk submission closes soon, submit your abstract now and join us in sunny Malta next May. 🌞 #FusionCellBio
Join us at our first DDM Summit diring the UEG week in Berlin ! 🎉 Very excited to organize this meeting with M. Heikenwälder and F. Real. This new meeting format is designed for basic and translational scientists interested in GI tract diseases and cancer. 📍 Join us onsite in Room New York!
Eine große Aufgabe und Verantwortung! Ich freue mich sehr weiterhin als Senatsvorsitzende zusammen mit den Senatsmitglieder die MedUni mitgestalten zu dürfen. Danke für das grosse Vertrauen!
MedUni Wien@meduniwien.ac.at · 10mo agoDer #Senat der #MedUniWien hat mit 1. Oktober die Arbeit aufgenommen. Die Funktionsperiode des Gremiums der #Universität läuft bis Ende September 2028. @maria-sibilia.bsky.social vom Zentrum für #Krebsforschung wurde erneut zur Vorsitzenden gewählt. ⬇️
🎤 Meet Our Speaker: Dr. @maria-sibilia.bsky.social , from Center for Cancer Research, Medical University of Vienna (Vienna, Austria) as a speaker at the Targeting RAS Symposium 2025. Dr. Sibilia will giver her talk during Session 10 on Day 3 at 11:15h. 🔗 https://targetingras.com/registration/
Our paper is now out with Cover! It reveals the specific role of EGFR in Ras mutant colorectal tumors which include metabolic rewiring, incresed stemness and more….all driven by Smoc2. have a look 👇👇🔝
EMBO Molecular Medicine@embomolmed.org · last yr.Our June issue is online! www.embopress.org/toc/17574684... The beautiful cover highlights the article by @maria-sibilia.bsky.social & al. on the tumor-intrinsic role of #EGFR in #KRAS mutant #ColorectalCancer 👉 doi.org/10.1038/s443... Scientific image: D. Kirchhofer, D. Krauß & M. Sibilia
Check out our new paper! We identified Smoc2 as an interesting target that is upregulated upon EGFR deletion, driving stemness signatures, reduction in cell size and metabolic rewiring. 💪 🔝👍
EMBO Molecular Medicine@embomolmed.org · last yr.Online today! 👉 #EGFR controls transcriptional & metabolic rewiring in KRASG12D #ColorectalCancer By D. Krauẞ, @maria-sibilia.bsky.social & colleagues at @meduniwien.ac.at 🗞️ doi.org/10.1038/s443...
I am deeply enthusiastic about contributing to elevate this journal to the highest ranks #science #drugdiscovery #openaccess #biomedicalresearch #cancer #aging #neurology #genomics #precisionmedicine #Elsevier
Can metastatic cancer be outsmarted by using the body’s innate immune system? At #CIMT2025, @maria-sibilia.bsky.social will present translational insights from mechanisms to therapeutics—exploring how the innate immune system can be harnessed to fight metastatic disease. www.meeting.cimt.eu
Vienna: start 13.00 in front of the main University building 🔝 👏👏
Stand Up for Science!@standupforscience.net · last yr.Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
Online now at Nature Cancer! @maria-sibilia.bsky.social and team propose a strategy to boost immunotherapy by combining topically applied TLR7/8 agonists with systemic interferon-I, sensitizing dendritic cells to produce IL-12 for tumor clearance 👇 www.nature.com/articles/s43...
Systemic IFN-I combined with topical TLR7/8 agonists promotes distant tumor suppression by c-Jun-dependent IL-12 expression in dendritic cells - Nature Cancer
Sanlorenzo et al. propose a strategy to boost immunotherapy by combining topically applied TLR7/8 agonists with systemic interferon-I, sensitizing dendritic cells to produce IL-12 for tumor clearance ...
nature.com
1/2 News from the Sibilia Lab 🔔 🔝Very excited about our very recent publication in @Nature Cancer 🔝🔝where we describe a new immunotherapeutic approach to treat topically accessible tumors like melanoma and breast cancer with the TLR7/8 agonist Imiquimod in combination with systemic Interferon.
2/2 This combination therapy shows efficacy against local tumors and distant metastases and sensitizes tumors to checkpoint inhibitors with enhanced memory formation. Check out the cool mechanism in our paper ⬇️ 👇 rdcu.be/d7c4X
Systemic IFN-I combined with topical TLR7/8 agonists promotes distant tumor suppression by c-Jun-dependent IL-12 expression in dendritic cells
Nature Cancer - Sanlorenzo et al. propose a strategy to boost immunotherapy by combining topically applied TLR7/8 agonists with systemic interferon-I, sensitizing dendritic cells to produce IL-12...
rdcu.be
I am extremely honored and proud to be invited as a speaker to this historical meeting celebrating the „EGF-receptor after 40 years“ organized at the #Royal-Society in London by Marc A. Lemmon from #YaleUniversity. A fantastic line-up of great contributors to the EGFR field #MedicalUniversityVienna
Our joint paper with the lab of Thomas Bauer is out in EMBO Mol Med. check it out and admire our beautiful cover! www.embopress.org/journal/1757...
EMBO Molecular Medicine
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
embopress.org
Very proud that Cristiano de Sa Fernandes received the Award of Excellence 2024 from the Austrian Ministry of Science for his PhD thesis performed in my laboratory on the „Role of Epigenetic modifications in Dendritic Cell Development and Function“. Congratulations, very well deserved 👏👏 #DC #cancer
A fantastic meeting #EMDS-2024 with lots of great speakers in a beautiful historical place #ÖAW in Vienna. Thanks to the organizers for putting together this great program. emds2024.com #DC #macrophages #myeloid-cells
