Interested in the Function and Regulation of #T6SS? Do you have relevant experience from your Master's project? Apply to this PhD position in our lab: www.biozentrum.unibas.ch/open-positio...

Have a look at our latest review on intracellular P. aeruginosa populations! @basler-lab.bsky.social @biozentrum.unibas.ch @nccr-antiresist.bsky.social

Trends in Microbiology@cp-trendsmicrobiol.bsky.social · last mo.

Intracellular Pseudomonas aeruginosa: internalization and survival

Our paper on a microbiology practical course for bachelor students focusing on T6SS dynamics, microbiology and fluorescence microscopy techniques is out @microbiologysociety.org, check it out! @basler-lab.bsky.social 👇 www.microbiologyresearch.org/content/jour...

Type VI secretion system-mediated bacterial antagonism in the classroom

The study of bacterial antagonism, and specifically type VI secretion system (T6SS)-mediated antagonism, has gained momentum over the last decade in research laboratories across the world. The T6SS is...

microbiologyresearch.org

Check out our new story on resistance to T6SS attacks! 👇

Will Smith@willpjsmith.bsky.social · 6mo ago

Here’s the latest preprint from my work on evolved resistance to Type VI Secretion system (T6SS) weaponry, funded by a @wellcometrust.bsky.social Sir Henry Wellcome Fellowship. So happy to see this out! www.biorxiv.org/content/10.6...

Here’s the latest preprint from my work on evolved resistance to Type VI Secretion system (T6SS) weaponry, funded by a @wellcometrust.bsky.social Sir Henry Wellcome Fellowship. So happy to see this out! www.biorxiv.org/content/10.6...

🙌 Congratulations to @atejadaarranz.bsky.social @basler-lab.bsky.social and Jenal Lab for this new @nccr-antiresist.bsky.social paper, another learning step about previously unknown bacterial vulnerabilities. #TransformingAntimicrobialResearch #AMR

Biozentrum, University of Basel@biozentrum.unibas.ch · 10mo ago

🧪 New research by @basler-lab.bsky.social reveals a surprising microbial trade-off: Pseudomonas aeruginosa activates a defense program to survive “speargun” attacks from rival bacteria, but this defense makes it more vulnerable to antibiotics. @unibas.ch @snsf.ch @nccr-antiresist.bsky.social 👇

Our paper is finally out! Check it out here 👇

Basler Lab@basler-lab.bsky.social · 10mo ago

Big congrats to @atejadaarranz.bsky.social and co-authors on this paper showing novel insights into the resistance to #T6SS effectors and an unexpected link to antibiotic resistance! Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab! rdcu.be/eShqI

Big congrats to @atejadaarranz.bsky.social and co-authors on this paper showing novel insights into the resistance to #T6SS effectors and an unexpected link to antibiotic resistance! Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab! rdcu.be/eShqI

Mechanisms of Pseudomonas aeruginosa resistance to type VI secretion system attacks

Nature Communications - Pseudomonas aeruginosa H1-T6SS delivers effectors in response to exogenous T6SS attacks. In this study, a CRISPRi screen identifies pathways involved in P. aeruginosa...

rdcu.be

Very happy to see this work published! We unveil a plasmid-chromosome crosstalk by showing that pOXA-48 encodes for a regulator that mediates the transcription of an enterobacterial chromosomal operon, resulting in a growth benefit for the plasmid-carrying bacteria! www.nature.com/articles/s41...

A plasmid-chromosome crosstalk in multidrug resistant enterobacteria - Nature Communications

The authors describe a new crosstalk between a globally disseminated carbapenem resistance plasmid and clinical enterobacteria clones. This crosstalk provides a fitness advantage to the plasmid-carryi...

nature.com

Podemos solicitar juntos este contrato predoctoral si quieres hacer la tesis en Ecología y Evolución de la Resistencia a los Antibióticos. www.cnb.csic.es/index.php/es... Más info en 🐥👇

Just joined the party here 🥳 So I drop here my last pre-print as well! More to come on this soon! www.biorxiv.org/content/10.1...

Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks

The Type VI Secretion Systems (T6SSs) is a molecular nanomachine that injects toxic effector proteins into the environment or neighbouring cells, and thus plays an important role in interbacterial com...

biorxiv.org