Read about the groundbreaking neuroscience research that UMass Chan faculty are doing: https://direc.to/o_Hn These interdisciplinary teams have received funding from the Dan and Diane Riccio Fund for Neuroscience. #neuroscience @reboldilab.bsky.social @sthyme.bsky.social @briankelch.bsky.social

I am excited to share that our work, in which we have dissected the signals driven by the nucleoside-modified mRNA and LNP components of mRNA vaccines that regulate germinal center (GC) responses, is now published in Cell! www.cell.com/cell/fulltex...

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

This study dissects the individual contributions of the different components of mRNA vaccines to immune responses. Nucleoside-modified mRNA promotes the production of type I interferons that act on de...

cell.com

Excited to be part of this Women in STEM Viepoint 🌟 Huge thanks to @jem.org for the invite - what an inspiring lineup!

Journal of Experimental Medicine@jem.org · last yr.

In this Viewpoint, we hear from a cross section of women, across multiple research fields, discussing their science and the process of setting up a lab as an independent researcher. rupress.org/jem/article/... @quinascience.bsky.social @aweinstock.bsky.social @osterhoutlab.bsky.social #WomeninSTEM

Why does selection feel so weak relative to mutation in affinity maturation? A new blog post giving three perspectives, including our new transformer-based model of natural selection on antibodies: matsen.group/general/202...

The term 'affinity maturation' understates the influence of somatic hypermutation

Three recent papers quantify how nucleotide-level mutation processes drive antibody evolution.

matsen.group

Dr. Andrea Reboldi from UMass Chan Medical School 🇺🇸 will be presenting his work on "Metabolic regulation of intestinal humoral response". Check his recent study on how receptor signaling controls gut humoral response: pubmed.ncbi.nlm.nih.gov/37714151/ @reboldilab.bsky.social #EMBOBarrierTissues

🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues. 📍 Where: Basel, Switzerland 📅 When: 26th–29th August 2025 📝 Registration deadline: 30th May 2025 Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social #EMBOBarrierTissues

Adaptive immunity in barrier tissues

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

meetings.embo.org

Kellog, @reboldilab.bsky.social, Vanni et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection. https://buff.ly/3CRIPNy 📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r

Follow our new podcast for more Mucosal Immunology - #MucosalMondays, coming to you the last Monday of every month.

Society for Mucosal Immunology@societymucosalimm.bsky.social · 2y ago

It's Coming! The Mucosal Immunology Podcast to launch on MONDAY! 🌟 Explore groundbreaking insights and inspiring stories in the world of mucosal immunology - brought to you by SMI and @mucosalimmunol.bsky.social. #MucosalImmunology #SciencePodcast #ImmunologyResearch #PodcastLaunch

Registration is live!! May 30th deadline for #EMBOTissueImmunity in Basel🇨🇭 (home to Eurocup 2025, Eurovision 2025, Art Basel, world renowned architecture and muuuuuch more!) Be our guest for groundbreaking #immunology discussion, swimming & fun along the Rhine. meetings.embo.org/event/25-bar...

Toronto-based ImmVue Therapeutics Inc. has licensed cancer-fighting technology from UMass Chan Medical School: direc.to/m4zC This partnership was facilitated by BRIDGE Innovation and Business Development at UMass Chan.

UMass Chan licenses potential small molecule immunotherapeutic for cancer treatment to ImmVue Therapeutics Inc.

Toronto-based ImmVue Therapeutics Inc. has exclusively licensed allosteric small molecule compounds identified in the laboratory of Joonsoo Kang.

direc.to

Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.

Microbiome-derived succinate-driven tuft cell hyperplasia in the colon helps defend against Clostridioides difficile infection, providing a pathway through which host/microbe interactions protect against pathogens doi.org/10.1084/jem.... @reboldilab.bsky.social @jexpmed.bsky.social

Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile

The microbial metabolite succinate promotes tuft cell hyperplasia, which enhances the gut’s ability to protect against intestinal infections. This study re

doi.org