Curious about how GTP hydrolysis occurs in small Rho GTPases? Check out our newly published JACS article! @jacs.acspublications.org Excellent work by @angelaparis3.bsky.social @rrozza.bsky.social pubs.acs.org/doi/abs/10.1...

Glutamine Tautomerization Drives RhoGAP-Aided GTP Hydrolysis in Small Rho GTPases

Rho GTPases promote GTP hydrolysis aided by specific GTPase-activating proteins (GAPs). By alternating between an active GTP-bound and an inactive GDP-bound state, Rho GTPases function as molecular sw...

pubs.acs.org

📢 Save the Date! We are thrilled to announce that the Congress of our Division will be held in Palermo. 🗓️ September 16-18, 2026. See you next year in Sicily! 🛍️As always, scholarships will be available for young researchers. The website will be available soon! #DCSB2026

Just published: RNA G-quadruplex folding mechanism via all-atom simulations in collaboration with my former PhD lab. Many thanks to Petr, Jiří, Vojtěch, and the reviewers, who encouraged us to pursue folding the full human telomeric G4. academic.oup.com/nar/article-...

RNA G-quadruplexes emerge from a compacted coil-like ensemble via multiple pathways

Abstract. RNA G-quadruplexes (rG4s) are emerging as vital structural elements involved in processes like gene regulation, translation, and genome stability

academic.oup.com

Our study is now published on JCIM🎉 We expanded and refined the preprint thanks to the insightful feedback from reviewers! paper: pubs.acs.org/doi/10.1021/... code: github.com/RitAreaScien...

Evolutionary Constraints Guide AlphaFold2 in Predicting Alternative Conformations and Inform Rational Mutation Design

Investigating structural variability is essential for understanding protein biological functions. Although AlphaFold2 accurately predicts static structures, it fails to capture the full spectrum of f...

pubs.acs.org

Almost at the end of the exciting @cecamevents.bsky.social conference 'RNA Modelling across scales' at SISSA, Trieste, Italy! 🎉 Fantastic speakers and great science. Organized with @bussigio.bsky.social @marcodevivo.bsky.social #RNA

Our integrative approach using #MD and #cryoEM data to construct structural ensembles of #RNA just published on @natcomms.bsky.social doi.org/10.1038/s414... Lead by Elisa Posani, with @magistratolab.bsky.social @bonomimax.bsky.social @pjanos.bsky.social @navtejtoor.bsky.social and Daniel Haack 🎉

We are sill accepting applications for poster presentations at the CECAM conference 'RNA Modelling Across Scales". Join us in the beautiful Trieste ☀️🏖️🏰! Apply now: www.cecam.org/workshop-det... Co-organized with @bussigio.bsky.social @marcodevivo.bsky.social

Tohle je moc pěkná věc. 😍 Oblek, který vás zneviditelní před dronem vybaveným termokamerou. Zdokonalený a vyrobený v České republice. Chceme jich koupit 333 pro ukrajinské speciály. Na půlku vybíráme peníze a druhou zaplatí partneři z ColtCZ. www.zbraneproukrajinu.cz/kampane/nevi...

333 neviditelných obleků pro ukrajinské speciály - Dárek pro Putina

Nebýt viděn je základ každého úspěšného boje. Teď v době, kdy na frontě vládnou drony vybavené termokamerami, je to čím dál těžší. Ale není to nemožné. Chceme na frontu poslat 333 speciálních nevidite...

zbraneproukrajinu.cz

Interested in understanding the molecular details of RNA–membrane association? Read our new paper just published in Nano Letters @acs.org. Excellent work done by sdimarco.bsky.social with Jana Aupic and @bussigio.bsky.social pubs.acs.org/doi/full/10.... #RNA #MembraneBiology #compchem #compbiol

All-Atom Simulations Elucidate the Molecular Mechanism Underlying RNA–Membrane Interactions

RNA–membrane interactions are starting to emerge as an important organizing force in both natural and synthetic biological systems. Notably, RNA molecules were recently discovered to be present on the...

pubs.acs.org

Very proud to announce that a member of our group, Dr. Jana Aupič, has been awarded the prestigious "EuChemS ChemBioLife Young Investigator" prize! 🏅 This honors her hard work and exceptional contribution to chemical biology. Congratulations, Jana! 🌟✨ . www.euchems.eu/divisions/ch...

News - EuChemS

WINNER ANNOUNCEMENT! “EuChemS ChemBioLife Young Investigator Award” 2024-2025 edition   We are proud to announce the winner of the EuChemS ChemBioLife Young Investigator Award  of the EuChemS Division...

euchems.eu

Today, we honor the defenders of Donetsk Airport—our legendary Cyborgs. Ten years ago, under relentless shelling for 242 days, they stood their ground and showed the world the unbreakable strength of Ukraine.

Just published in Journal of Chemical Information and Modeling our new study on the Mechanism of Rac1b: the Alternative Spliced Variant of Rac1 Small Rho GTPase. Great work by A. Parise and S. Cresca! pubs.acs.org/doi/10.1021/...

Assessing the Mechanism of Rac1b: An All-Atom Simulation Study of the Alternative Spliced Variant of Rac1 Small Rho GTPase

The Rho GTPase family plays a key role in cell migration, cytoskeletal dynamics, and intracellular signaling. Rac1 and its splice variant Rac1b, characterized by the insertion of an Extraloop, are fre...

pubs.acs.org

Prague's Kafka International Named Most Alienating Airport

Prague's Kafka International Named Most Alienating Airport

YouTube video by The Onion

youtube.com