Haikuo Li
@haikuoli.bsky.social
PI at SJTU (thelilab.github.io) Postdoc Yale | PhD WashU | BS SJTU | Interested in single-cell & spatial omics, epigenetics & genome science
Check out our recent review manuscript on spatial multiomics technologies!😀
JCI insight@insight.jci.org · 4w agoThis review by Haikuo Li @haikuoli.bsky.social & colleagues aims to equip researchers with an understanding of the current technological landscape and to accelerate the adoption of spatial multiomics methods in biomedical research: doi.org/10.1172/jci....
A new spatial transcriptomics approach eliminates the need for time-intensive imaging with specialized equipment, making the technique accessible to more researchers around the world. @naturebiotech.bsky.social
Scientists have developed a way to scale up spatial genomics and lower costs
A new computational approach eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue.
broad.io
#NewNProt: Protocol Extension describing joint spatially resolved epigenomic and transcriptomic profiling on a tissue section using #microfluidic chips bit.ly/4hLs7xT #spatialtranscriptomics #spatialepigenomics see also associated News & Views
Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq - Nature Protocols
In this Protocol Extension, the authors describe procedures for spatial barcoding in tissue sections using a microfluidic chip followed by sequencing-based joint genome-wide profiling of transcriptome...
bit.ly
Biological systems find ingenuous solutions. Almost anything that can happen, happens. Still, I would not have guessed a role of RNA-binding proteins on the cell surface. @raflynn5.bsky.social and his team are boldly investigating glycoRNAs and following their leads.
