3 great days at the SIC Summer School in Hornbæk with inspiring talks, short talks from young researchers, poster sessions, networking, and a trip to Esrum Abbey. Thank you to all speakers, participants, organisers, and the LEO Foundation for supporting the summer school. See you 24–26 May 2027.

Elimination of cancer T cells with little collateral damage to healthy T cells by TCRVβ-ADC Congratulations to Chella K Vadivel at the LEO Foundation Skin Immunology Research Center (SIC) and co-authors with this new treatment strategy published in Blood Adv 👌👏💪🎊🎉🎼 lnkd.in/e4mWCpUT

This work was spearheaded by Maria Gluud and the team at Skin Inflammation & Cancer @niels-odum.bsky.social at @sic-ucph.bsky.social and our fantastic collaborators! Finally, this study would not have been possible without the support from LEO Foundation, DFF, @cancer.dk @novo-nordisk.bsky.social

SIC’s annual activity report for 2025 is now available online. Read latest updates from the Center here: sic.ku.dk/news/2026/an...

SIC's Annual Activity Report 2025

sic.ku.dk

I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology. #TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance @sic-ucph.bsky.social @ludwigcancer.bsky.social doi.org/10.1126/scii...

Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF

Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF.

doi.org

SIC researchers have delved deeply into fibroblasts of the intestines. They describe how these cells organise our immune responses in structures called ‘gut associated lymphoid tissues’. @ursmoerbe.bsky.social sic.ku.dk/news/2026/fi...

Fibroblasts: Organizers of the intestinal immune system

Intestinal immune responses must be carefully balanced, as disruptions can lead to conditions such as inflammatory bowel disease. A new study sheds light on how immune cells are organized in the human...

sic.ku.dk

SIC researchers have found that Staph aureus on the skin releases toxins that activate both normal and cancerous T cells, leading to destruction of the skin barrier. Treatment with a new drug candidate, endolysins, can remove the bacteria and restore skin barrier function. sic.ku.dk/news/2026/st...

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Researchers from the LEO Foundation Skin Immunology Research Center (SIC) have made new insights into how Staphylococcus aureus augments skin barrier damage in Cutaneous T cell lym...

sic.ku.dk

Researchers at SIC recently characterised the diversity of phagocytes in the intestine of healthy people and in those with inflammatory bowel disease. They describe precursor phagocyte populations and the emergence of activated dendritic cells in IBD. sic.ku.dk/news/2026/di...

Diversity of mononuclear phagocyte populations in the healthy and inflamed human intestine

Researchers from the LEO Foundation Skin Immunology Research Center (SIC) at the University of Copenhagen have made new insights into the composition of antigen presenting cells in the intestines of p...

sic.ku.dk

Researchers at SIC have analysed the skin’s response to exposure to the contact allergen, nickel. They found that the response became more severe with repeated exposures and was likely due to a strong skin-resident T cell response to nickel. academic.oup.com/bjd/advance-...

Heterogeneous generation and expansion of epidermal-resident memory T cells in individuals allergic to nickel

Repeated nickel exposure in individuals allergic to the metal leads to increased clinical reactions. The clinical reactions correlate with an accumulation

academic.oup.com

📣 SIC Summer School 2026 — applications open! 📍Hornbæk, DK | 18–20 May 2026 🎯Theme: Skin Immunity & Homeostasis 💵Free (stay + meals). For PhD students & postdocs. ✍️Deadline: 15 Jan 2026 (23:59 CET). 🔗Full details: sic.ku.dk/summerschool/ 🔗Register here: eventsignup.ku.dk/sicss2026