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@gyrd-lab.bsky.social

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Meier Lab ICR@meierlabicr.bsky.social · 5mo ago

Our new study is out in Nature Communications. Using TNBC organoid mouse models, we show that necroptosis in both tumour and stromal compartments cooperatively drives effective responses to immunogenic cell death–based immunotherapy. 🔗 www.nature.com/articles/s41...

Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy - Nature Communications

Most advanced triple-negative breast cancers remain resistant to immunotherapy. Here, the authors discover that RIPK1-driven necroptosis in both tumor and stromal compartments is essential for effecti...

nature.com

Nature@nature.com · 4mo ago

Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools

Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

go.nature.com

@gyrd-lab.bsky.social · 4mo ago

I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology. #TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance @sic-ucph.bsky.social @ludwigcancer.bsky.social doi.org/10.1126/scii...

Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF

Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF.

doi.org

@gyrd-lab.bsky.social · 6mo ago

Join us for the EMBO workshop on Pathogen Immunity and Signalling #embopathogensignalling Abstract submission extended until 15 February. bsky.app/profile/embo...

EMBO@embo.org · 10mo ago

Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026. Abstract submission/Registration deadline: 1 February/15 March https://meetings.embo.org/event/26-pathogen-immunity #EMBOpathogenSignalling #EMBOevents 🧪

@gyrd-lab.bsky.social · 7mo ago

This is an excellent meeting for anyone interested in immunology, virology, host-pathogen interactions, immune signalling. Abstract submission deadline is 1 Feb.

EMBO@embo.org · 10mo ago

Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026. Abstract submission/Registration deadline: 1 February/15 March https://meetings.embo.org/event/26-pathogen-immunity #EMBOpathogenSignalling #EMBOevents 🧪

EMBO@embo.org · 10mo ago

Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026. Abstract submission/Registration deadline: 1 February/15 March https://meetings.embo.org/event/26-pathogen-immunity #EMBOpathogenSignalling #EMBOevents 🧪

Pathogen Immunity and Signalling

Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…

meetings.embo.org