We're excited to present a single-cell atlas of vertebrate cranial motor neuron development, the first story from my postdoctoral work in the Moens lab, up now on bioRxiv!
Shan Meltzer
@shanmeltzer.bsky.social
Assistant Professor at Vanderbilt University. HHMI Hanna Gray fellow. Studying the development of somatosensation.
Put my cards together to celebrate 20 years of studying biology 🎊 I guess I really like biology 😂
A paper in Nature Biotechnology presents a wearable ultrasound device that is optimized for continuous monitoring of pregnancies. go.nature.com/43zre6I #medsky 🧪
📢📢My lab at @VanderbiltU is hiring! We are looking for passionate Postdoctoral Fellows and Research Assistants to join our team investigating somatosensory development and repair. Please help me RT and share with your networks.
Thank you very much @hhmi-science.bsky.social for highlighting our work!!
Millions live w/ chronic pain & little relief. #HannaGray Fellow @shanmeltzer.bsky.social & team's new map of the spinal cord — built cell-by-cell — provides insights into how pain-signals travel, & will be openly available to the science community to help speed new pain treatments hhmi.news/4u1eIsJ
Excited to give a lecture to graduate students on touch and pain today! I took a pain course taught by David Julius and Allan Basbaum, which inspired me to study somatosensation development. Happy to pay it forward!🤗
Vanderbilt campus is beautiful and sparkly with all the ice!
The talent pool of international PhD applicants in bio is incredible🤯, but admissions are capped by funding. Private donors can make a huge impact in strengthening biomedical research by supporting international PhD students with fellowships.
Excited for a new year of discoveries, achievements and growth for the lab. There is so much to learn about somatosensory development!!
New preprint on sensory cortex dysfunction in Scn2a+/- mouse. Profoundly degraded sensory tuning and maps in S1--most dramatic of any ASD model. And rescued in post-critical period adults with CRISPRa. www.biorxiv.org/content/10.6...
Degraded sensory coding in a mouse model of Scn2a-related disorder and its rescue by CRISPRa gene activation
Heterozygous loss-of-function mutations in SCN2A , a sodium channel gene expressed in cortical pyramidal (PYR) cells, lead to a neurodevelopmental disorder characterized by autism, intellectual disabi...
biorxiv.org
Theoretically speaking, do you get infinite number of clusters if you sequence infinite number of cells? 🤔 Any thoughts would be welcomed
Really happy to share my career path at the Peking University biology alumni reunion. I attended the first reunion in 2009 at Hopkins and it was life changing to hear all the career stories. Happy to give back to the community!😊
Our Fall award applications are open! Check out the different opportunities to highlight incredible mentors, celebrate established leaders alongside up-and-coming talent, and so much more! Nominate someone or apply here: 👉 ow.ly/8nWy50WN3Uq #anatomy26 #AAA
Is any neuro PI willing to talk to me for 20 min and chat about NIH institutes and study sections for neuro research? Please DM me. Thank you!!
Who came up with the number 15% anyway?? It makes no sense and there is no justification on this number from NIH.
A great model for anxiety!
Robots vs rats! @adredish.bsky.social find that when a rat is attacked by a robot, hippocampal place fields develop to represent the #robot. When anxious, the rat imagines the robot's location, presumably worrying about the imminent danger 🧪 @plosbiology.org plos.io/4gRtgUX
Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits www.science.org/doi/10.1126/...
Differential encoding of mammalian proprioception by voltage-gated sodium channels
Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.
science.org
Delighted to highlight our new paper in @natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
Synaptic basis of feature selectivity in hippocampal neurons - Nature
A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.
nature.com