Thrilled to be in Uppsala 🇸🇪 for #WOMHER2026 filled of talks on women’s mental health. proud of @bonniee-leee.bsky.social @rominagl4.bsky.social @matejaperovic.bsky.social Laura Gravelsins for their great presentations that went off without a hitch (despite some lost luggage)

Do we really need to do research specifically on women's health? The REBOOT trial finds beta-blockers - a standard therapy for heart attacks - causes harm in women, but not men. Yes. The answer is yes. academic.oup.com/eurheartj/ar...

Beta-blockers after myocardial infarction: effects according to sex in the REBOOT trial

AbstractBackground and Aims. Recent trials have challenged the guideline recommendation of beta-blockers for post-myocardial infarction (MI) patients witho

academic.oup.com

✨ New Publication Feature ✨ How you take #menopausal #hormonetherapy may shape its impact on #cognition. A new study by Puri et al. from @liisagalea.bsky.social's group shows route of estradiol administration and cognitive domain matter. Learn more from the full paper here: 📖 ow.ly/ohlF50WNJiU

We’ve been working hard in the lab to understand the translational links to our preclinical work. Here’s our latest in preprint (& long time in process so many people to thank) but for now kudos to @bonniee-leee.bsky.social www.researchsquare.com/article/rs-7...

US POINTER study showed a significant improvement in global cognition for a structured intervention (physical, social, and cognitive activities, MIND diet, health monitoring) compared to self-guided intervention equivalent to 1-2 years of aging #AAIC2025. Evidence that behavior change can work

Alzheimer's Association@alzassociation.bsky.social · last yr.

Takeaways from U.S. POINTER top line results: ➡️ Both a structured & a self-guided intervention improved cognition, with the structured group improving even more. ➡️ Cognitive benefits were consistent across age, sex, ethnicity, heart health status and APOE e4 genotype. bit.ly/USPointerRel... #AAIC25

Really honoured to receive the @istaart.bsky.social Sex and Gender PIA Publication of the Year Award 🌟 Thank you to the PIA & @bucklr01.bsky.social! And ofc a big thank you to my co-authors, collaborators, & importantly, my supervisor @liisagalea.bsky.social 🙌 #endALZ @alzassociation.bsky.social

Looking forward to #AAIC2025!! Hope to see many of you there 🤩

Liisa Galea@liisagalea.bsky.social · last yr.

At #AAIC2025 in Toronto this coming week? Check out these talks and posters from the lab! Come say hi and let us know your thoughts! @bonniee-leee.bsky.social

Had a great time presenting my latest work on effects of pregnancy and AD risk on functional connectivity in middle age at #OSSD2025 🧠⚡️ Thank you @ossdcomm.bsky.social @whrcluster.bsky.social @camhnews.bsky.social #womenmind for hosting this fantastic Pre-Meeting and the opportunity to speak!!

Liisa Galea@liisagalea.bsky.social · last yr.

Up next @bonniee-leee.bsky.social on how previous parity influences functional connectivity in an animal model of Alzheimer risk (hApoe4) - bonnie calls this the Parity Paradox www.biorxiv.org/content/10.1...

Greetings from Albuquerque, New Mexico! We are ready for the @ossdcomm.bsky.social meeting! w/ @liisagalea.bsky.social @travisehodges.bsky.social @bonniee-leee.bsky.social

The end of a chapter.. 🥹💙 Endless thank yous to everyone who has been a part of this journey - lab mates and friends, other graduate students, mentors, collaborators, and of course, my supervisor, @liisagalea.bsky.social, for the support and mentorship over the years. #PhDone !!!!!! 👩🏻‍🎓

Jenn Kim@drjennkim.bsky.social · last yr.

Some of the graduating class of UBC Neuroscience PhDs at Grad 2025. Finally got to wear the floofy hat! Forever grateful for my time at UBC 💙💛 @bonniee-leee.bsky.social @dmcbrainhealth.bsky.social

Women and gender-diverse communities are facing renewed challenges as recent policy changes threaten access to healthcare and research support. Our latest blog explores how past advocacy efforts can guide us through today’s setbacks. 📖 Full blog: ow.ly/8RfJ50VylCo

I’m behind on sharing preprints because of …the rise of fascism but we need to celebrate wins. Here is @bonniee-leee.bsky.social ‘s last (but not least) paper of her PhD! On functional connectivity differences in middle-aged females based on parity and genotype! www.biorxiv.org/content/10.1...

Parity and APOEε4 genotype contribute distinct changes to functional connectivity across the middle-aged brain

Cognition and its underlying neurobiology change throughout the trajectory of aging, with prominent sex differences and influences of sex-specific factors. Research has shown that parity (pregnancy an...

biorxiv.org

Join us for a Multidisciplinary Look at Menopause! 🗓️ April 28 – 1:00 PM EST Hear insights from the next generation of menopause researchers! 🔗 Reserve your spot today for this hybrid event: ow.ly/T8g350VpOap #MenopauseResearch

Did you know that APOEe4, a genetic risk factor late-onset sporadic #AlzheimersDisease (AD) affects brain aging differently in males and females? 🧠 👀 📲 Swipe to learn more about this new study led by @bonniee_leee and click here to read the full paper: bsd.biomedcentral.com/articles/10....

Beyond grateful to everyone who has been part of this incredible journey 🩷✨

Liisa Galea@liisagalea.bsky.social · 2y ago

Tuesday we got to see @bonniee-leee.bsky.social transform into Dr.Bonnie Lee!! Many thanks to her committee, external examiner Kristen Zuloaga & university examiners Jessica Rosin and Wendy Robinson!!the second last UBC graduate student from the Galea lab to finish!! Thanks to UBC for the memories

Women's research remains underrepresented in scientific studies. That's why CAMH womenmind™ is committed to closing the gender gap in research with 30+ grants & awards distributed to advance women in science and research 💜. MORE: www.camh.ca/en/get-invol... #IDWGIS2025

New publication from my PhD research looking at influences of sex on brain health outcomes in a rodent model of Alzheimer’s disease (AD) risk 🎉: link.springer.com/article/10.1... Big thank you to the best co-authors, @liisagalea.bsky.social, Melike Cevizci, and Stephanie Lieblich 🙏

Sex-specific influences of APOEε4 genotype on hippocampal neurogenesis and progenitor cells in middle-aged rats - Biology of Sex Differences

Background Alzheimer’s disease (AD) disproportionately and uniquely affects females, and these sex differences are further exacerbated by the presence of Apolipoprotein (APOE) ε4 alleles, the top gene...

link.springer.com

Check out the full statement by Dr. Liisa Galea on our website: womenshealthresearchcluster.com/learn/womens...

Applications are now open for the ISTAART Ambassador Program 2025-26! This program offers early-career researchers access to #AAIC25, as well as year-round training, networking, and mentoring opportunities. Apply by Feb 10, 2025, at alz.org/ISTAARTambassadors!

A mouse hippocampus labeled for oligodendrocytes 🟡, myelin 🔵, and nuclei ⚪️. You can appreciate how the distribution of myelin and oligodendrocytes is not homogeneous in the overall hippocampal formation. #FluorescenceFriday

Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer’s Disease This further adds to the mounting evidence that microglia are perhaps much better at Aβ plaque formation than plaque clearance. What a fantastic study 🤩

Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer’s Disease - Nature Communications

The role of microglia in Alzheimer’s disease is debated. This paper shows that homeostatic microglia seed amyloid plaques in early disease stages and activated microglia compact plaques at later stage...

nature.com

Super proud of this one 🤩 Thank you to all my co-authors! Read it here now: www.nature.com/articles/s41...

Leveraging research into sex differences and steroid hormones to improve brain health - Nature Reviews Endocrinology

This Review outlines how the effects of steroid hormones on hippocampal neuroplasticity across the adult lifespan differ between the sexes, highlighting the importance of considering sex and steroid h...

nature.com

Liisa Galea@liisagalea.bsky.social · 2y ago

Our latest review-with @bonniee-leee.bsky.social where we pour our ❤️🧠 & soul to outline our position on why we are so passionate about harnessing the power of sex differences & within sex diff to propel precision medicine forward let us know if we convince you www.nature.com/articles/s41...