Excited to share this personal story published by @GeneticsGSA. A reflection on my journey in genetics, the many people who shaped it, the @haploteam and my enduring fascination with diversity. Thanks to everyone who has been part of the adventure! academic.oup.com/genetics/adv...

The genetics of the many forms of diversity

Abstract. The Genetics Society of America Medal honors an individual member of the Society for their contributions to the field of genetics at the midcaree

academic.oup.com

Excited to share our latest #haploteam paper! We developed a barcoded collection of 520 natural yeast isolates to screen 600+ compounds at population scale, uncovering how natural genetic variation shapes chemical responses. Congrats to Abhishek and Marion, who led this work! doi.org/10.1038/s414...

Population-scale chemical response revealed by a barcoded yeast collection - Nature Communications

The authors created a barcoded collection of 520 wild yeast strains and screened them against over 600 compounds, revealing how natural genetic variation shapes compound resistance and identifying gen...

doi.org

Our laboratory is looking for a PhD student in Functional Genomics (fully funded position). Expected starting date: Oct 2026 More info here: www.igbmc.fr/en/igbmc/lif... Please share 📨

IGBMC@igbmc.bsky.social · 2w ago

PhD position in Functional Genomics, in Raphaël Pantier's lab: Interplay between transcription factors and genome architecture in embryonic stem cells more info : amethis3.unistra.fr/amethis-clie...

Nice write-up of our latest paper: news.uark.edu/articles/82610 And could not have been done without the support of NSF and NIH.

New Study Finds Heat Shock Can Drive Changes in Protein Modifications

Research provides insight into how yeast cells respond to stressful conditions with implications for larger organisms that share the same proteins.

news.uark.edu

Jeff Lewis@lewislab.bsky.social · 3w ago

Excited to share the published version with some added experiments and analyses: link.springer.com/article/10.1...

Oh. Looky here #SciSky. New work from former PhD student Sabrina Chau along with our collaborators in the Laxman lab. A couple of main points: 1. Attenuation of a yeast dsRNA virus is accomplished through amino acid restriction.

Genetics Society of America@genetics-gsa.bsky.social · last mo.

Using genetic and biochemical experiments, @marcmeneghini.bsky.social and the team show how #yeast porin POR1 prevents an RNA mycovirus from accumulating to high levels in stationary phase cells following sustained culture. Read more in #GENETICS 🔗 buff.ly/UpebItI

Essays, written on the same occasion but a decade apart, by two lovers of genetics ❤️ @genetics-gsa.bsky.social @schacherer.bsky.social

Our new paper was, by definition, an adventure: stepping outside of our comfort zone, embracing the unknown, and engaging in activities where the outcome is uncertain. Includes discovery of a new species and working with a Native American tribe to name it… 🧵👇 onlinelibrary.wiley.com/doi/10.1002/...

Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus

Yeasts and related fungi isolated from cacti or nearby non-cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host.

onlinelibrary.wiley.com

Not being able to access the @ukbiobank.ac.uk is becoming a significant issue for a PhD student in our group and I can only imagine this is mirrored in many other places. It would be fantastic to at least have a timeline we could work with.

Our paper on the evolution of cellular miniaturization is now out in PNAS! www.pnas.org/doi/10.1073/... A short recap 🧵

Marco Fumasoni@marcofumasoni.bsky.social · 8mo ago

🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥 www.biorxiv.org/content/10.6...

Congratulations to @schacherer.bsky.social @unistra.fr recipient of the #Yeast26 GSA Medal! Great to hear the journey to identifying structural variants in #1011YeastGenomes, tackling heritability, genetic diversity, and genotype-phenotype @genetics-gsa.bsky.social

Super excited to share our lab's work led by PhD student Margot Ruffieux on domestication of Saccharomyces cerevisiae, with a focus on sourdough and baking associated yeast! 🍞

14th Ekiden for the HaploTeam already - I can't believe it. But first since we moved to @igbmc.bsky.social! The competition between the Haplo and Diplo subteams was tough but as always, great fun and team spirit!

⏰ Only 2 DAYS left for early registration! Join us at #Yeast26 (June 13-17, Pacific Grove, CA) for cutting-edge research in #genetics, #genomics, #disease, #regulation, #systemsBiology, #cellBiology, #lifeCycle, #syntheticBiology, & more. Register by April 16 to save! 🧬 genetics-gsa.org/yeast-2026/

New from my lab: Ancestral sequence reconstruction analysis indicates the furin-cleavage-site insertion in the SARS-CoV-2 spike gene likely interrupted a codon academic.oup.com/ve/article/1...

Ancestral sequence reconstruction analysis indicates the S1/S2 insertion in the SARS-CoV-2 spike gene likely interrupted a codon

Abstract. The genome of the seasonal acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has a 12-nucleotide insertion that produced a furin cleava

academic.oup.com

🌊 Get ready for YGM2026- the ultimate #Yeast genetics experience! World-class science meets Pacific Grove paradise June 13-17 🏨 Stay on-site: deadline April 8 ⏰ Conference registration ends April 22 This is THE meeting you don't want to miss! We'll see you there! #Yeast26 #Asilomar #YeastGenetics

🎤 Meet the PYFF9 speakers! Yeast & Fungi Conference 2026 in Valencia (8–11 Sept) 📢 Registration & abstract submission open 🔗 yeastfungi.efbiotechnology.org/home #Yeast #Fungi #Biotechnology #CallForAbstracts @pyff-9.bsky.social

#Yeast #Genetics Meeting 2026 is in June - Abstract deadline is TODAY! Submit your abstract, attend the meeting this summer in Pacific Grove, CA at #Asilomar Conference Grounds, a 107-acre protected coastal state park located on the Monterey Peninsula. #Yeast26 #YGM2026 genetics-gsa.org/yeast-2026/

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations. www.evocellnet.com/2026/03/mapp...

Mapping the yeast atructural interactome with AlphaFold3: an open call for collaboration

We are excited to announce the early-stage release of our S. cerevisiae  structural interactome mapping project. Using AlphaFold3 (AF3), w...

evocellnet.com

📢 Reminder: March 5 is the abstract submission deadline for the Yeast Genetics Meeting. Don’t miss the chance to share your work—submit an abstract and encourage colleagues to attend! genetics-gsa.org/yeast-2026/

Homepage - Yeast Genetics Meeting 2026

Visit our website to learn more.

genetics-gsa.org

Thrilled and honored to be part of the 2026 GSA Award recipient! This honor reflects years of teamwork - huge thanks to everyone who has been part of the #haploteam. Proud to share this with you all! @genetics-gsa.bsky.social genestogenomes.org/the-2026-gsa...

The 2026 GSA Awards: The brightest geneticists combine intellect with excellence in education, research, and mentorship

This year’s award recipients bring to the table expertise and leadership that have shaped, and will shape, science for years to come.

genestogenomes.org

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD. www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

Sad to learn that David Botstein has passed away. Few people truly shape how you think and do science, and David was definitely one of them. I had a fun and influential time at Princeton with the Botstein, Kruglyak and co gangs. It shaped the way I do science. www.online-tribute.com/DavidBotstein

David Botstein | 1942 - 2026 | Online-Tribute.com

David was a beloved husband, father, brother, scientist, teacher, mentor, musician, friend, who touched the lives of thousands. David’s wide-ranging scientific career spanned decades with a legacy o…

online-tribute.com

www.biorxiv.org/content/10.6... comparison of commercially available #Saccharomyces #mead yeasts. Our new preprint w/ @balintnemeth.bsky.social and colleagues compares 13 mead #yeast strains for their phenotype, genome, and presents data on metabolites in experimental mead fermentations.

Finally…

New Perspective!🔥It's fascinating how scientists from different fields but interested in the same question [e.g. genotype-phenoytpe relationship] can have such different perspectives. Here we put in our 2 cents wrt genetic effects being context-dependent, and pheno variation being mostly polygenic

Beyond Mendel: a call to revisit the genotype–phenotype map through new experimental paradigms

Abstract. The long-standing notion that genotypes map to phenotypes through simple one gene–one trait relationships continues to shape both research in the

academic.oup.com

Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14

Ancient co-option of LTR retrotransposons as yeast centromeres - Nature

Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

nature.com

With @litinice.bsky.social, we built a haploid resource from 33 wild Taiwanese Saccharomyces cerevisiae strains — including some of the most genetically divergent Asian lineages — to bring natural yeast diversity into a genetically tractable framework. www.biorxiv.org/content/10.6...

Registration is open for the inaugural GRC conference in the Function of Evolving Systems. Aug 9-14, 2026, Waterville Valley. Truly stellar speaker lineup. Student/postdoc fellowships are available! Please come join us! www.grc.org/function-of-... @joybergelson.bsky.social

New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways www.biorxiv.org/content/10.6...

Excited to announce our latest publication in reporting evidence for three (3!) new whole genome duplications (WGDs) in yeasts. Scientists have often wondered why WGD is so rare in fungi, it turns out we may just not have been looking hard enough! 🧪 🍄 🧬 www.sciencedirect.com/science/arti...

Discovery of additional ancient genome duplications in yeasts

Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

sciencedirect.com