New research by the @ninacabezas.bsky.social lab & collaborators from @uniklinik-fr.bsky.social. A vitamin A metabolite may offer a targeted therapeutic strategy for heart attack patients by regulating HSCs to minimize excessive inflammation and preserve long-term heart function.

Healing a broken heart

A vitamin A metabolite, 4-oxo-retinoic acid, can regulate the activity of hematopoietic stem cells and thereby reduce inflammation after a heart attack, ultimately improving heart function in the long...

ie-freiburg.mpg.de

A bit of the backstory to our recent Nature paper. Find out more in the „behind the paper“ with @hi_stem_lab @dkfz.bsky.social Thanks again to all the co-authors specifically @simon-renders-md.bsky.social and Jasper Panten communities.springernature.com/posts/chasin...

Chasing Ghosts – The Quest to Capture Neurons in Pancreatic Cancer

Neurons infiltrate pancreatic tumors, yet their molecular identity has remained elusive . How do these nerves shape the tumor microenvironment and influence cancer progression? Using Trace-n-Seq, we m...

communities.springernature.com

A technology to identify and profile mouse neurons that connect the spinal cord to pancreatic cancer might improve treatment of this disease https://go.nature.com/40ZoYUK

Pinpointing neurons that hinder cancer treatment

Method to identify neurons associated with pancreatic cancer.

go.nature.com

oops, actually three cancer neuroscience papers, number three, very cool combination of retrograde tracing and single cell analyses: www.nature.com/articles/s41...

Also getting highlighted by @erictopol.bsky.social is clearly a bucket list achievement. ☺️☺️☺️

Eric Topol@erictopol.bsky.social · 2y ago

Today @nature.com on how pancreatic cancer can hijack our nervous system and how denervation may be therapeutic www.nature.com/articles/s41...

A great ride with amazing @verat-h.bsky.social and @jasperpanten.bsky.social with Andreas Trumpp @dkfz.bsky.social - we hope this leads to more elegant biology and clinical translation in PDAC and beyond. www.nature.com/articles/s41... Perspective @nature.com www.nature.com/articles/d41...

@verat-h.bsky.social · 2y ago

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

Today @nature.com on how pancreatic cancer can hijack our nervous system and how denervation may be therapeutic www.nature.com/articles/s41...