Does anyone know of a good updated figure likes this showing the correlation between transposons and genome size? No taxa preference. @transposableman.bsky.social?
Xueying Li
@3xueying.bsky.social
Faculty at Beijing Normal University. Evolutionary genetics with yeast and flies. Alumni of @EMBL @WUSTL @PKU https://free-mask-7f6.notion.site/li-lab-bnu
Our latest contribution on #regulatoryevolution in which we show that the shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations. Led by @simonaube.bsky.social www.nature.com/articles/s41...
The shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations - Nature Ecology & Evolution
Saturation mutagenesis of the FCY1 promoter in budding yeast shows that adaptation to 5-fluorocytosine is not accessible through single cis-regulatory mutations, despite large mutational effects on pr...
nature.com
Our latest paper on how transcription factor binding sites for global regulators can evolve in bacteria is now published in eLife! Mutation by mutation, we are uncovering the regulatory landscapes of bacteria. elifesciences.org/digests/1037...
Step by mutational step
New bacterial regulatory interactions can evolve more readily than previously appreciated, providing new insights into the evolution of gene regulation.
elifesciences.org
It was a great pleasure to attend this workshop. The most wonderful interactions with colleagues and lots of new thoughts on GRN evolution. Thank you all ❤️
Thank you to organisers to James Hombría and Antónia Monteiro @monteirolab.bsky.social and everyone who joined us at this week's Workshop on 'Novelty, Co-option and Divergence During Gene Network Evolution' biologists.com/workshops #BiologistsWorkshops
Take 30 scientists at all career stages, interested in the evolution of gene regulatory networks, lock them in an English country house for 4 days, feed them and give them unlimited amounts of alcohol. What do you get? Probably the most exciting conference I have ever attended. #BiologistsWorkshops
Very pleased with the response and still have spots & funding especially for students/postdocs. Sign up soon before it gets full. If you are working at or wanting to learn about the intersection of functional biology and ecology/evolution, you would get a lot of it! www.grc.org/function-of-...
Function of Evolving Systems - Gordon Research Conferences
GRC presents Function of Evolving Systems, a conference on .
grc.org
Please join us in NH (perfect place to be in August!) for this inspiring conference organized by @petrovadmitri.bsky.social and Joy Bergelson. Very interdisciplinary, so I look forward to learning tons of new concepts. www.grc.org/function-of-...
Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357
Happy to share that our preprint is now out! We discuss how Synthetic Biology can be used as a powerful tool to answer questions in evolutionary biology. We hope it will be a useful resource for the community! With @3xueying.bsky.social and @hhydrochaerus.bsky.social ecoevorxiv.org/repository/v...
Synthetic biology as an empirical tool for evolutionary theory
ecoevorxiv.org
Excited to share my first preprint from my PhD w/ @justinmcrocker.bsky.social. We show that cell type-specific regulatory dominance promotes robustness and evolutionary innovation through interallelic transcriptional hubs, potentially expanding the mutational paths available to diploids. (1/18)
Interallelic cis-regulatory dominance promotes robustness and evolutionary innovation https://www.biorxiv.org/content/10.64898/2026.03.17.712157v1
The origin of our eyes over half a billion years ago is looking more and more weird--from a cyclops to four eyes to two. Here's my story (gift link): nyti.ms/4rzisQP
Happy to share a recent publication to which I contributed as a corr. author: www.nature.com/articles/s41... This work is in collaboration with Dr. Yao Yu at Fudan University, where the team managed to transfer S. cerevisiae chromosmes into K. marxianus, a species diverged from Sc ~114 mya. (1/4)
Intergeneric chromosomal transfer in yeast results in improved phenotypes and widespread transcriptional responses - Nature Communications
Transferring genetic materials between distantly related yeasts, presents technical challenges but can yield industrially interesting phenotypes. Here the authors establish a method to transfer indivi...
nature.com
Happy Darwin Day to all! To celebrate can you comment with your favorite paper on evolutionary biology from the last few years? Whatever comes to mind and whichever paper that really changed your view of evolution.
Our new micropub is out, where we evolve yeast strains that are both scientifically interesting and practically useful! Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast doi.org/10.17912/mic...
Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast | microPublication
doi.org
Looking for something new to integrate into an #evolution or #microbiology course? Useful for lectures, labs, homework? Have a look at our STEPS program, which simulates bacterial evolution, including the #LTEE. Easy web-based interface & lab manual w/ exercises to help develop students' intuition.
Excited to share new #program, STEPS, which can simulate #dynamics of the E. coli Long-Term Evolution Experiment (#LTEE) or other microbes in serial transfer regime. telliamedrevisited.wordpress.com/2025/08/12/s... STEPS developed by @devinmlake.bsky.social, Zachary Matson, Minako Izutsu, and me.
#ICYMI Most read articles @the-node.bsky.social in May include two articles from #MetabolismMondays series covering diverse aspects of metabolism research using #Drosophila. Lautaro Gandara from @justinmcrocker.bsky.social lab @embl.org talks about the impact of toxins on insect physiology.
From Shifting Skies to Toxic Tides: A Tale of Flies & Flux #MetabolismMondays - the Node
All the world's a metabolic dance, early career scientists are leading the way! Emerging perspectives in metabolism Dr. Lautaro Gandara This week we will
thenode.biologists.com
Can you believe Nemo came from one of these? 🕵️♂️ More fish eggs to study!! 🤩📊🔬
Elegant new theory on polygenic adaptation by Will Milligan, Laura Heyward, and Guy Sella.
When should adaptation arise from a polygenic response versus few large effect changes? https://www.biorxiv.org/content/10.1101/2025.05.15.654234v1