Tessera
Folgen

Shefali

@iamshef.bsky.social

Seeking postdoc positions | PhD candidate | AHA Predoc Fellow | Studying metabolism and development in the Tennessen Lab at IU Bloomington | She is into dancing and Drosophila 💃🏽🎶🎙️👩🏽‍🔬🔬

950 Posts1103 Follower1487 Folgt
Drew Schreiner@schreinerdrew.bsky.social · yesterday

He also has one of my favorite quotes: If one wishes to understand the behavior of animals, one must take account of their individuality, annoying as this may be for those who prefer the tidiness of physics, chemistry, and mathematical formulations. -Donald Griffin

Greg Priest@gregpriest.bsky.social · 2d ago

Donald Griffin, discoverer of bat echolocation, was born OTD 1915. I imagine “small mammals enough like ourselves to feel that I could understand what their lives would be like, and yet different enough to make it a sort of adventure and exploration to see what they were doing.” 🐋🌱🧪 #HistSTM

Fig. 11 from Griffin, Echoes of Bats and Men (1959). “The frequency and wave length of a bat's sound vary during each chirp. This diagram, which is approximately to scale, illustrates the small amount of sound reflected by one insect.”I
Rebekah Rogers@evolscientist.bsky.social · yesterday

Officially recruiting postdocs at GW. If you are interested in genetic novelty, structural variation, or evo genetics please get in touch! We have data sets on mulitple organisms with large population sizes (Drosophila, Megalonaias nervosa) and species in decline (fireflies, mussels, elephants).

Mark Peifer (He, him)@peiferlabunc.bsky.social · 2d ago

Incredible example of how having the nervous system connectome can empower extremely surprising insights about the control of flight physiology (and that demonstrates why Drosophila is at the cutting edge of neuroscience) 🧪

Yichen Luo 骆奕辰@camellyc.bsky.social · 2d ago

1/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6...

Shefali@iamshef.bsky.social · 2d ago

This is such amazing and elegant work using the power of #Drosophila to find such exciting and intriguing insights about breathing! Kudos to the entire team 👏🏽🎉🥳

Yichen Luo 骆奕辰@camellyc.bsky.social · 2d ago

1/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6...

Katherine Aird@airdlab.bsky.social · 6d ago

Thrilled to see our work on senescence & metastasis out! We found that chemotherapy increases ovarian cancer metastasis in a paracrine manner via fructose. Dietary fructose is sufficient to increase metastatis. This work has multiple implications related to both chemo and diet.

Nature Aging@nataging.nature.com · 7d ago

Online now!✨Cole et al identify fructose as a component of the therapy-induced SASP in senescent ovarian cancer cells and show that it reprograms cancer cells in paracrine, promoting detachment and metastasis @airdlab.bsky.social @wistar.org

Tim Mosca (he/him)@drosophilosophy.bsky.social · last wk.

Amazing invited speakers! You're in for a real treat folks ... but ONLY if you attend #Dros27 in the City of Brotherly Love, Philadelphia! February 2027!

Genetics Society of America@genetics-gsa.bsky.social · last wk.

Meet three of our #Dros27 plenary speakers! 🧠 Vanessa Auld 🪰 @nabroderick.bsy.social 🧬 Don Fox From glial biology to host-microbe interactions to genome stability and regeneration, they'll bring exciting science to Philadelphia. 🔗https://buff.ly/7IBPyFM

Shefali@iamshef.bsky.social · last wk.

The most amazing thing about the #Drosophila #community is how eagerly we all share resources with each other. I needed an antibody and we reached out to a colleague on Friday and they already shipped it out this morning. Couldn't be more grateful 😊🥹 👩🏽‍🔬🪰

Annika Barber@annikabarber.bsky.social · 2w ago

Raced home from vacation so we could submit and preprint postdoc @keisukefukumura.bsky.social's paper! It's an exciting first foray for our lab into the periphery, where we find a unique role for CLOCK in regulating lifespan on high fat diet. 🧪https://doi.org/10.64898/2026.07.20.739608

Fat body CLOCK restrains innate immunity and maintains survival under dietary stress in Drosophila

Both aging and a high-fat diet (HFD) dampen circadian gene transcription rhythms and promote chronic inflammation. How aging and HFD interact to affect peripheral molecular clocks and circadian behavi...

doi.org

Shefali@iamshef.bsky.social · 2w ago

Saying goodbyes is hard - esp a friend who could see through me without needing too many words, whom I saw grow up from an undergrad to postbac to now an incoming grad student at another university. I am sure they'll kick ass at whatever they do, but it'll be strange not seeing them in the hallway 🥹

Benoit Bruneau@benoitbruneau.bsky.social · 2w ago

our paper starts with an analysis of the dynamics of 3D chromatin in cardiac differentiation, for ventricular and atrial cardiomyocytes. They are different! And by single cell methyl-HiC we can discern subtype differences. www.science.org/doi/10.1126/...

Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease–linked transcription factor

Dosage-sensitive transcription factors (TFs) underlie altered gene regulation in human developmental disorders, and cell type–specific gene regulation is linked to the reorganization of three-dimensio...

science.org

Juan Angueyra@juanonyme.bsky.social · 2w ago

Timely preprint from our Fadool lab friends finds even more interactions and interesting biology with these genes! www.biorxiv.org/content/10.6...

Subfunctionalization of tbx2 paralogues during photoreceptor cell specification in zebrafish

Zebrafish possess three distinct sources of retinal progenitors that produce identical photoreceptor subtypes throughout life. All photoreceptor progenitors simultaneously express multiple transcripti...

biorxiv.org

Shefali@iamshef.bsky.social · 2w ago

I am still not over the #Fifa final and how calm the #spain team was - they kept their head in the game, had max ball possession, and waited patiently for their win. Lesson learnt : In a world full of chaos, work hard, do what you do best and wait patiently for your win like #spain ⚽🎉