Doc Edge

@docedge.bsky.social

Associate professor in quantitative and computational biology @USC. Genetics, evolution, statistics. https://edgepopgen.github.io/edgelab/

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS

In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

pnas.org

The anatomy of an AI-supported academic article is becoming more apparent. I desk reviewed ~70 manuscripts this week for our journal. Reckon 20ish had significant AI assistance. On top of hundreds of others recently I'm starting to see patterns. Are other editors are seeing the same or similar? 1/

It’s truly astonishing to see how comprehensively the US government is tearing down every part of the system that has made it up until now a world-leading power in science, research, and technological development. The entire world will suffer from this wanton destruction.

Dan Vergano@danvergano.bsky.social · 2mo ago

White House proposes new rules giving political appointees final approval of research grants These proposed Office of Management and Budget regulations would render the federal research grant review process opaque www.scientificamerican.com/article/whit...

I am beyond excited to announce that I will be joining the Dept. of Biosciences at Rice as an Assistant Professor this summer! I’m incredibly grateful to my mentors and colleagues for their guidance and encouragement throughout this journey. More soon—I’ll be recruiting students and postdocs!

Hi Genetics/Comp-Bio community 👋 Interested in mentoring a comp-bio research student in East Africa over the summer? Do you have any experience in bioinformatics, biostats, genome/RNA-seq analyses, ML, or metagenomics? We'd love to have you as a mentor in our new program! 🧵 (1/n)

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Please repost: My department at USC is hiring for a teaching-track faculty position. We are looking for someone principally to teach statistics for biologists, but there will be opportunities for other courses in statistics & algorithms applied to biology usccareers.usc.edu/job/los-ange...

Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

Learn more about applying for Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

usccareers.usc.edu

Delighted to share our latest research from the 23andMe Research Team, just published in @nature.com ! We looked at data from >27,000 participants to uncover how human genetics influences weight loss efficacy and side effects of GLP-1 medications like semaglutide. A short thread 🧵👇

“We’ve lost out on the ability to continue to improve this work to make it more effective, and to explore how to apply it to other areas…There are a lot of different ways that genetics has been used to justify prejudice and…that human-made social categories interface with biological categories“🧪

A star scientist showed that better genetics lessons could reduce racism. It was the death knell for his career

Brian Donovan had persuaded high school teachers and education researchers that prejudice might be ended by changing how genetics is taught.

statnews.com

We're already losing a generation of scientists because of the things this administration has done. Grad students not admitted, faculty jobs not available. It's a crisis we won't see the cost of for 10 years but we'll feel it

Jenna Norton@jenna-m-norton.bsky.social · 4mo ago

This isn’t a “could face” situation. It’s a “are facing” situation. And brain drain will continue to happen as long as we undermine science in the US. www.nytimes.com/2026/04/04/b...

Why do schizophrenia GWAS signals look so flat across the genome? In our recent preprint, we explored why psychiatric disorders — and, more broadly, brain-related traits involving the central nervous system — appear to have unusual genetic architectures. 🧵1/n

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