Dr. Ari Kozik

@drkozik.bsky.social

Scientist. Prevotella Host-Microbe Interactions. Airway Microbiome. Multi-omics. Asst. Prof @ UMich. PI of @koziklab Nerd. https://sites.lsa.umich.edu/koziklab/

With Prevotella recently split into many new genera (over 55 species down to ~21!), what's left? Our new review explores the remaining mucosal species, with a particular focus implications for the human oral, airway, and vaginal niches. 🧪 Journal of Bacteriology journals.asm.org/doi/10.1128/...

The redefined identity of Prevotella: new implications for oral, respiratory, and vaginal health | Journal of Bacteriology

Over a century ago, Dr. William Wherry and his student, Wade Oliver, reported the isolation of a bacterium they called Bacterium melaninogenicus (1). This organism was described as a pigmented, Gram-negative, strictly anaerobic organism found frequently in the human mouth on carious teeth, but also recovered from the throat, tonsils, genitalia, and wound abscesses. Later classified under the genus Bacteroides, these and related organisms were frequently described as difficult to grow and maintain in pure culture, with biochemical assays yielding inconsistent fermentation and proteolytic profiles (2, 3). In 1947, Schwabacher, Lucas, and Rimington found that the characteristic pigments were not composed of melanin, as the name suggests, but rather hematin (4). In the 1960s, others showed that some strains required both hemin and vitamin K/vitamin K derivatives for growth (5). Consequently, as similar organisms were isolated from human oral and mucosal sites in the following decades, Shah and Collins proposed the reclassification of several species into their own genus, Prevotella, in 1990. Shah and Collins had previously argued that Bacteroides contained considerable heterogeneity, particularly with regard to fermentative capacity. They suggested that inclusion in Bacteroides should be limited only to highly fermentative species phenotypically similar to B. fragilis. The “nonsaccharolytic Bacteroides” were reclassified into the genus Porphyromonas, while the remaining 15 “moderately saccharolytic Bacteriodes” became Prevotella. Using a combination of biochemical and 16S rRNA-based analyses, they described Prevotella as organisms that may or may not produce pigment, are sensitive to bile salts, are moderately saccharolytic, and lack both glucose 6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH) (6).

journals.asm.org

🧪 Excited to finally share the published version of our work showing that P. melaninogenica (affectionately called 'P. mel' in my lab) has more superpowers... Aerotolerant capacity of the lung symbiont Prevotella melaninogenica | Journal of Bacteriology journals.asm.org/doi/10.1128/...

Aerotolerant capacity of the lung symbiont Prevotella melaninogenica | Journal of Bacteriology

This study provides a correction to the 100-year-old classification of Prevotella melaninogenica as a strict obligate anaerobe. We demonstrate that this key member of the human microbiome is capable o...

journals.asm.org

Returned safely from my first ASM as a lab group! We had five posters and my students did a great job with their presentations! Special shoutout to @clairealbright.bsky.social whose manuscript was accepted right before we arrived! 🧪

Claire E Albright@clairealbright.bsky.social · 2mo ago

Had the best time at #ASMMicrobe2026 presenting my research along with other members of the Kozik Lab!🔬 Science was shared, colleagues were met, and lots of free merch was taken! 🦠 Looking forward to next year!

Just when we think we've got them figured out, bacteria find a way to surprise us. For a century we've been calling Prevotella melaninogenica a strict anaerobe (oxygen =☠️), but its been chillin' in oxygen rich parts of the body -- the respiratory tract 👄🫁. A thread on a new preprint from my lab🧵:

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 7mo ago

Aerotolerant Capacity of the Lung Commensal Prevotella melaninogenica https://www.biorxiv.org/content/10.64898/2026.01.19.700327v1

I am pleased to announce the submission of my first author manuscript, "Aerotolerant Capacity of the Lung Commensal Prevotella melaninogenica," now available as a preprint. 🧫🧫🧫 Thank you to my mentors Dr. Ariangela Kozik @drkozik.bsky.social and Dr. Gary Huffnagle at UM.

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 7mo ago

Aerotolerant Capacity of the Lung Commensal Prevotella melaninogenica https://www.biorxiv.org/content/10.64898/2026.01.19.700327v1

My senior thesis was titled “The osteological manifestations of enslavement” The number of parry fractures in adult and sub-adult bones was heartbreaking. (A parry fracture is a broken ulna resulting from trying to block a direct strike to the face or upper body)

Rude1 Haunted Badness. ⁂@rude1.blacksky.team · 12mo ago

idk - branding humans like cattle, chaining them to dead bodies, feeding them to each other, filling them with gunpowder then blowing them up, burying them alive for insects to eat -- it being so bad mothers killed their children and people jumped from ships to drown seems, like, super bad dude

BRANDING BLACKNESS

BIOMETRIC TECHNOLOGY AND THE SURVEILLANCE OF BLACKNESS

Two days before embarkation, the head of every male and female is neatly shaved; and if the cargo belongs to several owners, each mans brand is im¬ pressed on the body of his respective negro. This operation is performed with pieces of silver wire, or small irons fashioned into the merchant s initials.

—Theodore canot, Memoirs of a Slave Trader

We have been branded by Cartesian philosophy.

—aime cesaire, Discourse on Colonialism

Let’s face it. I am a marked woman, but not everybody knows my name.

—HORTENSE SPILLERS

You can find Wilson Chinn on eBay.com or other online auction sites for sale among antebellum ephemera. Wilson Chinn’s portrait was taken around 1863 by Myron H. Kimball, a photographer with an interest in da¬ guerreotype and a correspondent with the Philadelphia Enquirer during New York’s 1853 World’s Fair. Kimball also served as an official photogra¬ pher for the Freedman’s Bureau. In this particular portrait, a chain is tied around Chinn’s ankle and various tools of torture lie at his feet: a paddle, a leg iron, a metal prodding device. The caption below the image reads, “exhibiting Instruments of Torture used to punish slaves.” The carte de visite (figure 3.1) captures Wilson Chinn’s stare at the camera. Particularly striking is the “longhorn,” or pronged metal collar, fastened around Chinn’s neck. An 1862 copy of Harper’s Weekly describes this torture device as con¬ sisting of three metal prongs, “each two feet in length, with a ring on the end,” to which would be attached a chain to “secure the victim beyond all

WILSON OHINN, a Branded Blare (Mm Louiaiana Alan exhibiting Inatrumenta of Torture uaed to puniah Slarea.

Photographed by Hob*LI, 477 Broadway, N. V Entered according to Act of Cougrru. In the year lttO. by Gbq. H. Hans, In the Clerk’• 0 ®c« of tne United States for the Southern Dlatrlct of New*Tork.

If you applied to assistant professor positions in North America in 2024-2025, we want to hear from you as we continue to collect data on the applicant experience. Thanks also to @bwfund.bsky.social for their support of our work! Link to 2024-25 Applicant Survey. und.qualtrics.com/jfe/form/SV_...

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Thrilled to share the first preprint from my group! Prevotella are predominant but understudied members of the respiratory microbiome. They have a reputation for being hard to work with, but understanding them is likely important for understanding how they contribute to respiratory health. 🧫🔬

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · last yr.

Development of a basal media for carbon utilization assay and analysis of the starch utilization locus in Prevotella melaninogenica https://www.biorxiv.org/content/10.1101/2025.07.04.663206v1

This. And that’s IF you can afford to be away for 5 days and you have enough support to keep things going while away. I can only sometimes manage this once per year unless the location is nearby. My spouse does not have the same kind of flexibility with his job and that’s a big deal.

Dr. Kat Napaaqtuk❄️@napaaqtuk.bsky.social · last yr.

That brings up another good hybrid point....for me to travel to a meeting on the west coast means a full day of travel and another back, so a 3 day meeting is actually 5 days away from my kids. In person only meetings suck for parents. Thanks for making that point

"We’re talking about biomedical research as a whole. Here there’s no question of false hope or over-promising. We’ve been at this for 80 years...It’s no hyperbole to say that wrecking biomedical research now will leave many of us without cures or treatments in the future. It’s close to a certainty."

Josh Marshall@joshtpm.bsky.social · last yr.

A Path Forward to Save American Bio-Medical Research talkingpointsmemo.com/edblog/a-pat...

Today is World Asthma Day! I am a respiratory microbiome scientist partly because of my specific interest in understanding asthma. It is a condition that asserts the interconnectedness of our bodies with our environment. It is complex, dynamic, and life-altering.

Colorful graphic that says World Asthma Day, May 6, 2025. Make inhaled treatments accessible for ALL! Global Initative for Asthma. ginasthma.org @ginasthma

"I would not have dared to dream that metastatic melanoma would become a treatable disease in my lifetime. Yet here we are today, with 43% of people diagnosed with metastatic melanoma living 10 years or more, due to treatments that we broadly refer to as cancer immunotherapy." Barry P. Sleckman, UAB

Needhi Bhalla 💅🏽@needhibhalla.bsky.social · last yr.

The Senate Committee on Appropriations is holding a hearing on Biomedical Research: Keeping America’s Edge in Innovation on April 30 at 10:30am ET, chaired by Senator Susan Collins 🧪 www.appropriations.senate.gov/hearings/bio...