Dr Bilgili showed us the outcomes after OHTx divided by need of ECMO at 72 hours post surgery. ECMO need at 72 hours greatly worsens survival.

Dr Huang shows pre and post allocation change status change in immunosuppression and outcomes among multi-organ transplant. Super interesting data. @ishlt.bsky.social #ISHLT2025

Dr Elbert Heng shows amazing study on survival of patients with ACHD receiving OHTx vs multiorgan transplant alone. ❤️ and 🫁 carry the worse survival so far. @ishlt.bsky.social #ISHLT2025

Dr Paula Ramirez shows us their new predictive models to discriminate if ❤️ and kidney transplant is superior to kidney after ❤️. Beautiful work which can help change clinical practice at #ISHLT2025 @ishlt.bsky.social

Amazing work presented from Dr Topkara who developed a kidney risk score which predicts the risk for AKI/HD after ❤️ transplant! High AUC, higher than eGFR alone! #ISHLT2025 @ishlt.bsky.social

Dr Hussain showed us a single center experience of Fontain patients receiving ❤️ transplant. Should they get a liver as well? Seems like all 24 of them had recovery of the liver function after transplant without needing a a new liver. Great science at #ISHLT2025 @ishlt.bsky.social

Finally we talk about induction with Dr Barten. To induce or not to induce? This is the dilemma! And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.

It’s AB0ut time we talk with Dr Aversa about AB0! Super interesting case of an 0 patient receiving nonA1 🫁 transplant with no signs of rejections. Incredible science showed at #ISHLT2025 @ishlt.bsky.social

Followed by Dr Guillaime Coutance guiding us through PRAs. Which antibodies should we look for and how to measure??? Dr Lyster showed us what to do with highly sensitised patients pre and post transplant. #ISHLT2025

And last day at #ISHLT2025 we go through the consensus statement with Dr Annette Jackson. Amazing talk on the use of antibodies in transplant. @ishlt.bsky.social

This morning at ISHLT I’m sensing a theme, let’s see if any of you catch on that. Rare causes of PH. @ishlt.bsky.social #PAH #PH #Rightventricle #rare

We finish with a great talk from the amazing @nickbruin.bsky.social about the Delphi consensus. Refer early and often Reassess your patient. 🫁 transplant save lives and improves quality of life in PAH #PAH #PH #lungtransplant #ISHLT2025 @ishlt.bsky.social onlinelibrary.wiley.com/doi/full/10....

Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute

Lung transplantation is indicated for selected patients with advanced pulmonary arterial hypertension (PAH). We used a modified Delphi process to develop recommendations on care of patients with PAH ...

onlinelibrary.wiley.com

What is the role of MCS in PAH and cardiogenic shock? 1) patient selection 2) choose the RIGHT access 3) have an exit strategy in view 4) start PH therapies 5) consider transplant These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social #ISHLT #PAH #PH

What can you do when a patient with PH land in the ICU with Shock? Dr Mads Andersen walks us through Preload treatment Inotropes and its use Afterload for PH Important talk @ishlt.bsky.social #ISHLT2025 #PH

And from the Right Ventricle- Right atria interaction we move to the complex relationship between heart - kidneys and lungs in PH with an amazing talk from Dr. Rosenkranz. #ISHLT2025 #PAH #PH @ishlt.bsky.social

Today we dig deep in the pathophys of PH #ISHLT2025 with Dr Frances De Man on pressure loop of the RA. Super interesting discussion on what happens to myocites in the right atrium. @ishlt.bsky.social #PAH #PH

Today @ishlt.bsky.social in Boston we talked about Pulmonary Hypertension. Here the main take-away from the Updates on the 7th World Symposium.

In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias jamanetwork.com/journals/jam...

Another study on the striking effect of sotatercept in PAH patients with elevated REVEAL score. Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43) www.nejm.org/doi/full/10....

Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death | NEJM

Sotatercept improves exercise capacity and delays the time to clinical worsening in patients with World Health Organization (WHO) functional class II or III pulmonary arterial hypertension. The eff...

nejm.org

DAPA-TAVI: The #SGLT2 inhibitor dapagliflozin was superior to standard care alone in decreasing rates of all-cause mortality or worsening #HeartFailure in older adults w/ #vhdAS undergoing TAVI, resulting in a 28% relative risk ↘️. #ACC25 More: bit.ly/4cfLNsy #cvSurg #CardioSky #MedSky

Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social

Vutrisiran is now approved for aTTR cardiac amyloid! Another medication to help these patients! www.businesswire.com/news/home/20...

Alnylam Announces FDA Approval of AMVUTTRA® (vutrisiran), the First RNAi Therapeutic to Reduce Cardiovascular Death, Hospitalizations and Urgent Heart Failure Visits in Adults with ATTR Amyloidosis wi...

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced the U.S. Food and Drug Administration (FDA) approval of ...

businesswire.com

One of my best friends: Create your Instagram and find happiness, Stop being a Hippie already! @alvarezsoto.bsky.social

Linguine with mussels. ❤️

Check out this paper from Sweden. Long term use of LDL lowering meds and anti-HTN meds was associated with lower the odds of dementia in this case-control study. No reason not to lower BP and cholesterol. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Use of common cardiovascular disease drugs and risk of dementia: A case–control study in Swedish national register data

INTRODUCTION Cardiovascular drug use may help prevent dementia; however, current evidence is mixed. Using a case–control design, we investigated the association between duration and combination of m...

alz-journals.onlinelibrary.wiley.com

I’ll diet on Monday… Chocolate chip cookies 🍪🍪🍪🍪

Happy #FridayThe13th - and if you're transplanting, fear not! This research group found no superstitious effect of Friday the 13ths or Full Moons on cardiac transplant outcomes, acuity, and volume. #JHLT #heartTx #cardiosky #transplantsky @uofpenn.bsky.social www.jhltonline.org/article/S105...

🚨 Big news in lipidology! 🚨 @newamsterdampharma.bsky.social's Phase 3 BROADWAY trial results for Obicetrapib are in: ✅ 33% LDL-C reduction at day 84 (vs placebo) ✅ 21% reduction in MACE after 1 year A promising advance for patients with #ASCVD & HeFH! #Cardiology #Lipidology

Simgle combined measure of hsCRP, LDL & Lp(a) among initially healthy U.S. women was predictive of incident CV events during a 30-yr period #CardioSky #MedSky #NEJM @drmarthagulati.bsky.social @erinmichos.bsky.social @michaeldshapiro.bsky.social @drlipid.bsky.social www.nejm.org/doi/full/10....

On #GivingTuesday we give to a lot of things that we are passionate about. For those of us who are #SouthAsian please consider giving to ourhealthstudy.com so we can help save the hearts & lives of our community. Consider a donation today 📎 because.massgeneral.org/campaign/our...