Puja Mehta 🧩 🌻
@drpujamehta1.bsky.social
Physician-Scientist MD PhD Rheumatologist investigating immune mechanisms of ILD 🖐️ 🫁 Cross-speciality Rheum-Pulm 🤝 All the -omics! 🥼 👩🔬 🧬 Science Communication 🗣️ Leadership 💪🏼 U.K.-USA 🇬🇧 🇺🇸 Opinions are my own 😊
Pleased to share our message in The Lancet: "Protect Early Career Researchers through fair authorship governance" co-authored with Carola Garcia de Vinuesa www.thelancet.com/journals/lan...
Protecting early-career researchers through fair authorship governance
In academia, authorship symbolises both currency and trust. Authorship buys credibility, funding, promotion, visibility, mobility, and opportunity. For early-career researchers, manuscript authorship ...
thelancet.com
Gollum, Goldilocks and Pinnochio have no place in academia. The 'Gollum Effect' www.nature.com/articles/d41... 44% had experienced it. Of these, 18% had experienced it many times. In 46% the perpetrator was a high-profile researcher, and 35% said it was their supervisor. My slide below:
Brilliant 😂 @pwgtennant.bsky.social @rheumcat.bsky.social @killianhurley.bsky.social Only someone famous like @kaminskimed.bsky.social could do this tho!! youtube.com/shorts/zPqGq...
The best scientific abstract ever?
YouTube video by Recreational Science
youtube.com
@thanhneville.medsky.social is a magician!!! 🪄 I cannot believe that I can now get 2 uses out of spring onions. Every day is a school day!
Maybe in the future….but not just yet!
Katharine Hayhoe@katharinehayhoe.com · 8mo agoBluesky is the new science Twitter, new study by @whysharksmatter.bsky.social and Julia Wester concludes! "Results show that for every reported professional benefit that scientists once gained from Twitter, scientists can now gain that benefit more effectively on Bluesky than on Twitter."
Happy International Day of Women and Girls in Science / STEM 🧬 Science is stronger when everyone has a 🪑 Seat AND a 🗣️ Voice at the table! #ThisisYale #IWDGS
I choose YALE! Excited to share I’ve started my first faculty position: Assistant Professor Physician–Scientist Yale School of Medicine My research focuses on immune mechanisms in Systemic Autoimmune Rheumatic Disease (SARD)-ILD, supported by an amazing mentorship team. Reach out to collaborate!
Is MIF the missing link between AT2 & macrophages in Pulmonary Fibrosis? See "Dysregulated Alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling" Kudos Drs Kim, Sauler & team! #CurePF4All www.science.org/doi/10.1126/...
Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling
Impaired proteostasis amplifies alveolar epithelial MIF signaling to macrophages, increasing profibrotic macrophages and driving lung fibrosis.
science.org
An incredible honour to be included in this Nature Reviews Rheumatology feature - a 20-year reflection on women in rheumatology. 💜💜💜 Huge thanks to the wonderful @ashira-md.bsky.social & Dr. Grace Wright for co-authoring such an inspiring piece. 🤩. #WomeninRheum www.nature.com/articles/s41...
A 20-year reflection on women in rheumatology - Nature Reviews Rheumatology
The collective priorities of the rheumatology field represent the lived experience, and therefore diversity of its members. The ‘mould’ of rheumatology, that is, its culture, structures and expectations, was not created for or by women, but women have slowly changed this mould to make space for diverse perspectives.
nature.com
PhD-done ✅ 🙌 Huge thanks to my examiners @profmarciniak.bsky.social from University of Cambridge and Dr. James Harker from @imperialcollegeldn.bsky.social for such a thorough & engaging viva voce - a journey thru immune mechanisms of fibrotic lung disease Grateful & excited for what’s next! 🎓✨
An important day of remembrance — not just for the USA 🇺🇸 but for all of us around the world 🌍. I was at Yale last year on 9/11 and was deeply moved by how they marked the occasion. #911Memorial reminds us of the value of unity, resilience, and compassion in the face of tragedy
Dr. Nathan A Smith@drnathanasmith.bsky.social · last yr.Today, we remember and honor the lives lost on 9/11. Let us never forget the heroes who emerged in the face of tragedy and the resilience of a nation united in hope and strength. #NeverForget #911Memorial
Really pleased to hear that our #EULAR2025 symposium was covered by the European Medical Journal (EMJ) A Podcast with all the speakers in the session, including Prof Gerd Burmester covering mechanisms of methotrexate use wrt vaccines and me covering the Lungs 🫁! lnkd.in/en6vw26j
This link will take you to a page that’s not on LinkedIn
lnkd.in
Forgot to post this! Shout out to my awesome friends, colleagues, collaborators at #EULAR2025 Very pleased to have delivered 2 talks and caught up with amazing people from all over the world!
Finally out! The first AI regenerative model applied to IPF & PCLS single nuclear sequencing data is out & it works!! See 🧵 below and paper here www.nature.com/articles/s41... #CureIPF #ScienceMatters
A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases - Nature Biomedical Engineering
UNAGI deciphers cellular dynamics from human disease time-series single-cell data and facilitates in silico drug perturbations to discover drugs potentially active against complex human diseases.
nature.com
Yumin Zheng@yuminzheng.bsky.social · last yr.1/n Happy to share our new single-cell+unsupervised AI drug discovery method is now published in Nature Biomedical Engineering!🚀 Huge thanks to Dr. Ding, @kaminskimed.bsky.social and all collaborators. 🎉 We hope UNAGI can accelerate the discovery of new drugs. doi.org/10.1038/s415... #singlecell
Can’t wait to read!
KaminskiMed@kaminskimed.bsky.social · last yr.Finally out as reprint!!! "Alveolar epithelial cell plasticity & injury memory in human pulmonary fibrosis". Glad to share the results of our single nuc-seq & single cell ATAC-seq analyses of human IPF & PCLS before peer review - see the key findings in 🧵👇🏽 www.biorxiv.org/content/10.1...
Delighted to be a small part of this effort led by @epirheum.bsky.social !
Rheum Cat@rheumcat.bsky.social · last yr.📢 New in RMD Open: The CORDIALITY Review explores how social media can be leveraged to support rheumatology professionals & patients, especially in underserved regions and for marginalized populations 🔗 pubmed.ncbi.nlm.nih.gov/40154563/
Day2 #BSR2025 Join us! ⏰ 1740 Exchange 9! 🗣️ Me - Lungs 🫁 and Liver Fibrosis 🗣️ @synovialjoints Prof Antoni Chan Optimising conventional treatment 🪑 Nicola Wood See you later!! ✌️
Day 1 : Rheum-Haem 🩸 🗣️ #Castlemans Disease: Relevance in Rheumatology ⏰ Today 5:55pm, Exchange 11 🤝 Join @MarkBishton (cons Haematologist, Nottingham) and I See you later!! ✌️ #BSR2025
All set for #BSR25 in Manchester?? Looking forward to 3⃣Days 3⃣Talks, covering 4⃣ Specialities! - Rheum-Pulm-Haem-Liver 🖐️🫁🩸 1⃣ common thread... Cross-speciality Immunology :) Holler if you're there...and Come say hi!👋 @rheumatologyuk.bsky.social
Six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others #IWD #InternationalWomensDay https://go.nature.com/43w9Voe
Behind every great woman in science, there’s another great woman in science
Nature - To mark International Women’s Day on 8 March, six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others.
go.nature.com
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...
Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics
Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...
doi.org
@nisreenalwan.bsky.social so pleased to find you here
