Remembering Robin Williams on the anniversary of his passing. His humor, kindness, and incredible talent continue to touch our hearts and inspire us every day. (July 21, 1951 – August 11, 2014)
Ryan Townley
@drtfromkc.bsky.social
Girl dad x 3 👸 | Dog dad x 2 🐶| Cognitive & Behavioral Neurologist 🧠| Program Director 🎬| Leading clinical trials in AD, DLB, and FTD. 👨🔬🔬Unraveling the mysteries of the mind, one axon at a time.
Personalized neoantigen vaccines vs cancer: we've seen benefits for pancreatic, renal and melanoma. Today initial, encouraging results vs glioblastoma in 9 patients with this deadly brain cancer www.nature.com/articles/s43...
Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial - Nature Cancer
Johanns and colleagues report the results (including safety, efficacy and immunogenicity) of a phase 1 clinical trial of a DNA-based personalized therapeutic cancer vaccine administered following surg...
nature.com
In his 2nd Inaugural, Abraham Lincoln delivered what might be the most devastating rebuttal to the Both Sides lie in history. "Both parties deprecated war but one of them would make war rather than let the nation survive, and the other would accept war rather than let it perish. And the war came."
Spiralling global temperatures (1850-2026) It is exactly 10 years since I first put this animated graphic of changes in global temperature online. #ClimateSpiral It instantly went viral. People watched it over and over again. It still offers the power to shock a decade on.
October is Lewy Body Awareness month. Please see attached educational opportunity for both medical professionals and families this Saturday morning on Zoom:
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system erictopol.substack.com/p/our-braini...
FIRST ON CNN: Dramatic lifestyle changes can fight early-stage Alzheimer’s, study says. Here’s how | CNN www.cnn.com/2025/07/...
FIRST ON CNN: Dramatic lifestyle changes can fight early-stage Alzheimer’s, study says. Here’s how | CNN
Adopting intensive lifestyle changes can slow or stop progression of early-stage Alzheimer’s disease, according to a new study.
cnn.com
What's the optimal number of steps of physical activity this is associated with multiple (9) favorable outcomes? The largest, systematic review of 57 studies, 35 cohorts. 7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis
Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...
thelancet.com
I seriously think the Social Internet is 21st century cigarettes. Complete with secondary smoke causing a lot of harm in nonusers.
This fits with my theories here of dementia being a multiple hit hypothesis and structural changes over a decade before lay the groundwork for brain failure in the setting of cognitive/systemic stressors.
Ian Kremer@wolverinebear.bsky.social · last yr.Amazing thread. Trump has shown us on countless occasions that he has no shame. It’s more troublesome that there are enough like minded individuals he has surrounded himself with to propagate this metastatic hate.
Scott Delaney@scott-delaney.bsky.social · last yr.I'm sorry. I stopped typing and just listened. I'll post summaries as they're published. But the end was that Judge Young went on to defend judicial independence and to underscore the perilous moment in American history where racial discrimination is tolerated. He ends with "Have we no shame?"
“A society grows great when old men plant trees whose shade they know they shall never sit in.” — Greek proverb
Astrocytes have long been conceived as passive support player cells in the brain. But today @science.org (via 3 reports) they got a big upgrade for their active role in neuromodulation and control of brain function www.science.org/doi/10.1126/...
Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4
Contrary to Clear, Verifiable Facts, Secretary Kennedy Continues to Repeat Harmful Myths About Alzheimer’s and Dementia Research
The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.
bit.ly
🔥 Most important paper I've read all year🔥 👉 Injury/disease doesn't reliably predict pain 👉 Biomarkers alone can't explain pain 👉 PSYCHOSOCIAL factors reliably determine chronic pain 👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors www.nature.com/articles/s41...
Biological markers and psychosocial factors predict chronic pain conditions - Nature Human Behaviour
Fillingim et al. show that biological and psychosocial factors jointly predict conditions associated with chronic pain.
nature.com
I just really need everybody to understand that everything that’s happening in and to the global economy now (and all the businesses and people in it) is the entirely predictable result of the intentional decisions of one guy who doesn’t understand how the global economy works.
The gylmphatics of our brain, which clear waste products, interact with our immune system and are key to preserving brain health, modulating its aging process, and propensity for neurodegenerative diseases A superb review @cp-immunity.bsky.social @jonykipnis.bsky.social
Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.
Almost every line of this story would have been simply unbelievable a few months ago: —Pioneering cancer researcher; —*Arrested* at airport in Boston; —Now indefinite ICE detention in Louisiana; —"Crime": not declaring some frog-embryo samples for research. Read it. www.nbcnews.com/news/us-news...
New images could change cancer diagnostics, but ICE detained the Harvard scientist who analyzes them
Without scientist Kseniia Petrova’s expertise, no one can fully unlock the data’s potential, putting crucial advancements in early cancer detection at risk.
nbcnews.com
Personally, I think it should be front page news for at least a month if a sitting US President is using falsified evidence to try and deny due process to a man who has committed no crime, but that’s just me
We've seen videos like this before, but usually when you see a tearful wife pleading with the kidnappers who have taken her husband, she's not talking to the U.S. president
Aaron Rupar@atrupar.com · last yr.Abrego Garcia's wife: "I will not stop fighting until I see my husband alive. Kilmar, if you can hear me, stay strong. God hasn't forgotten about you. Our children are asking when you will come home ... they miss their dad so much."
“Inside that tiny speck is an entire architecture like an exquisite forest..." 🧠❤️ #neuroskyence www.theguardian.com/science/2025...
US scientists create most comprehensive circuit diagram of mammalian brain
The 3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring
theguardian.com
Lifestyle matters!! KU has put together our LEAP (Lifestyle Enrichment for Alzheimer’s Prevention) www.kumc.edu/research/alz...
Lifestyle Empowerment for Alzheimer's Prevention (LEAP!)
Small lifestyle changes in diet, exercise, sleep and other areas can positively influence your risk of Alzheimer's.
kumc.edu
Eric Topol@erictopol.bsky.social · last yr.When you can accurately predict risk of Alzheimer's from blood biomarkers (p-tau217) and do something about it. www.cnn.com/2025/04/07/h...
The penguins are globalists and rich liberal elitists. Just look how they’re dressed.
NBC News@nbcnews.com · last yr.