@drummonk.bsky.social and I wrote a @plosbiology.org Primer to highlight a fantastic study by Aalim Weljie’s and Amita Sehgal’s groups that reveals time-of-day dependent activities of glucose metabolic pathways. journals.plos.org/plosbiology/...
Circadian clock gates diurnal glucose utilization
The circadian clock and cellular metabolism are tightly coupled. This primer discusses a recent PLOS study that elucidates how glucose metabolism changes over the course of the day in Drosophila and h...
journals.plos.org
PLOS Biology@plosbiology.org · 4mo agoHow do #circadian clocks regulate glucose processing? By integrating human metabolite profiling with isotope-tracing in #Drosophila, this study defines daily rhythms in #glucose utilization that are influenced by circadian timing @plosbiology.org 🧪 plos.io/3Olm1M1
Adaptation to daily environmental changes shaped self-sustained circadian oscillators. We wrote a dispatch on Current Biology to highlight the new papers from Carl Johnson and Michael Rust group. They found seasonal environmental changes select for self-sustained oscillators. Read their works!!
Joanna Chiu@joanna-chiu.bsky.social · 5mo agoSelf-sustained Circadian Oscillators Confer Enhanced Fitness Under Changing Photoperiods ☀️ @currentbiology.bsky.social @drummonk.bsky.social and I wrote a dispatch on fascinating back to back pubs from the labs of Carl Johnson and Michael Rust. www.sciencedirect.com/science/arti...
Thrilled to share our new work! In this study, we have expanded on the role of the circadian clock in integrating seasonal environmental cues through splicing. Thanks to @joanna-chiu.bsky.social for the continuous mentorship and to all co-authors! www.biorxiv.org/content/10.1...
Splicing of a core clock gene regulates seasonal adaptations by a winter gating mechanism
Seasons bring changes to the environment. Many organisms adjust their physiology and behavior in response to seasonal changes in order to survive. Although the molecular mechanisms mediating the integ...
biorxiv.org
Our paper is published in PLOS Biology! journals.plos.org/plosbiology/.... What a long and rewarding journey with @joanna-chiu.bsky.social and many who are not on Bluesky.
O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing
The liver transcriptome is highly sensitive to metabolic cues. By characterizing nuclear protein O-GlcNAcylation in the mouse liver over the course of the day and in response to altered meal timing, t...
journals.plos.org
Hi everyone! Finally joined BlueSky and found everyone is here!! Starting my journey here with a clip of my drumming🤘Foot technique is challenging!!