tl;dr: MissAlignment learns to score misalignment then wiggles your alignments around to reduce that misalignment -> no more misalignment = high res STA 🌟 Watching @martenchaillet.bsky.social chip away at this was a real privilege! I’m excited to see this out and what you all will do with it 🙃

Dimitry Tegunov@dtegunov.bsky.social · 3mo ago

We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

Happy to share that the bulk of my PhD work is now on bioRxiv! We followed SsdA, the A. nidulans ortholog of yeast RNA-binding protein Ssd1, and found it forms motile mRNP puncta in hyphae. [1/7] www.biorxiv.org/content/10.6...

The molecular architecture of tunneling nanotubes https://www.biorxiv.org/content/10.64898/2026.05.27.728322v1

New preprint alert! Ever wonder if cells can talk to each other? Tunneling nanotubes (TNTs) are tiny bridges between cells used to pass organelles, nucleic acids, proteins & even viruses but we've never seen inside them clearly. Until now! 👇🧵 biorxiv.org/content/10.64898/2026.05.27.728322v1

Congratulations to lead author Noor Alam, and present/past lab members: TJ Holt, AndY Schaefer, Franklin Mayca-Pozo, Sarath Reghunathan, Sarah Butts, Priyanka Bhakt, and Iliana Kesisova, who've worked on this since 2019 🎉 Read the preprint 👇 biorxiv.org/content/10.64898/2026.05.06.723191v1

A new Profile is now published in #CYTOSKELETON!!! "Foundational Discoveries in #Actin Regulation: An Interview With Tom Pollard". This is a must read for all actin fans. Huge thanks to Alfred Chin and @evakarasmanis.bsky.social for putting this together. onlinelibrary.wiley.com/doi/10.1002/...

Foundational Discoveries in Actin Regulation: An Interview With Tom Pollard

Dr. Thomas D. Pollard's work transformed cytoskeleton research into a quantitative, mechanistic science. Over five decades, he established core principles of actin dynamics, including filament polari....

onlinelibrary.wiley.com

Attention graduate students...ONLY 1 WEEK until the submission deadline (June 2, 2025) to be a #cytoskeletonscholar. Apply today! #CYTOSKELETON

We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...

LAST CALL for FASEB Septins - Spatial Regulators of Cell Biology June 15-19, Niagara Falls, New York Register now: events.faseb.org/event/septin... Submit abstract by Monday or DM me after that. 80 participants and counting cant be wrong!

Join us for the exciting Cell Dynamics Symposium at Vanderbilt! Poster deadline coming up May 12th. Everyone welcome - please repost!

As the incoming Chair of Biochemistry and Biophysics at Weill Cornell Medicine, I am looking for a Director of Research. Exciting opportunity for a PhD scientist to shape the future of this new Department! Apply here: jobs.weill.cornell.edu/NY/job/New-Y...

Life in the lab can be a constant give and take, HHMI scientists say: science doesn’t happen without collaboration. That’s why HHMI programs support scientists at all career phases: : www.hhmi.org/programs

🚀Ever wondered if there's a universal rule of spindle scaling across eukaryotes? Turns out, there is! Our study reveals an evolutionarily conserved principle driven by a surprising factor: chromosome crowding. 🧵👇 shorturl.at/MmPNr

Ready to apply? Submit your materials by March 3, 2025 to Associate Editorial Board Chair, Justin Parreno at: jparreno@udel.edu #Cytoskeleton #ScienceOpportunities #Trainees (4/4)

Exciting opportunity for Graduate student trainees in cytoskeletal research! Apply to be a Cytoskeleton Scholar! 🌟 Selected by the Associate Editorial Board, scholars will gain recognition & networking opportunities. (1/4)

I am excited for this opportunity to chair the Department of Biochemistry and Biophysics at Weill Cornell Medicine! news.weill.cornell.edu/news/2025/01...