@evakaulich.bsky.social

Neuroscientist, curious about the dynamics of mRNA and proteins at synapses. Postdoc at MPI for Brain Research, Schuman Lab. she/her

Today we report the directed evolution of HUH into rHUH, a sequence-specific covalent protein tag for RNA labeling. rHUH was hard to engineer: the initial HUH template had no RNA activity, so we started with RNA-DNA hybrids. 30 rounds of selection on the yeast surface were required, and 7 cycles of

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119 EMBO Fellows from 30+ countries attended the EMBO Fellows’ Meeting in Heidelberg, DE from 27 June–1 July. #Research was shared and connections formed – an incredible opportunity for #networking and #collaboration. Thank you to all who joined and were part of this vibrant community! 🧪

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NEW Paper: If you're a fan of Rachel from 'Friends', you would love OSP-1, as it is also protective of ROS Donato et al. found a novel gene OSP-1 (oxidative stress protective 1) that protects neurons from damage caused by reactive oxygen species (ROS), by modulating autophagy.👇

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How hard do bacteria-eating nematodes bite in order to break the bacterial cell wall? Check out our new paper, led by Jason Casar & collab with Jen Dionne, using pressure sensing beads that change color upon compression (bluetorial coming soon) rdcu.be/d5n7v

Upconverting microgauges reveal intraluminal force dynamics in vivo

Nature - Nanoparticle-based ‘microgauges’ are developed for in vivo force sensing and deployed in C. elegans to investigate how mechanical force correlates with electrical signalling in...

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