Evan Irving-Pease

@evanirvingpease.bsky.social

PI at the Big Data Institute, University of Oxford Royal Society University Research Fellow aDNA | Complex Traits | Selection | Disease | Domestication 🇦🇺🇬🇧💀🧬🦠🐕

Delighted to have been awarded an ERC Advanced Grant for 'Stocking the Past' which will investigate the balance between arable farming and stockkeeping in Neolithic and Bronze Age Britain and Ireland using a range of isotopic and genomic approaches with a great team. Should be fun!

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New preprint! "Joint dog and wolf genealogies reveal the evolution of the canine genome" We build genealogies of dogs and wolves to find two strong mutation-rate pulses, GC-biased gene conversion, selection, and inter-species gene flow shaping the canine genome. www.biorxiv.org/content/10.6...

Joint dog and wolf genealogies reveal the evolution of the canine genome

Dogs and their closest extant relative, the grey wolf, diverged around 30k years ago, but have since experienced complex histories of gene flow involving other canids, adaptive pressures due to close ...

biorxiv.org

🚨 PhD Studentship Alert 🚨 4-year DPhil in Genomic Medicine and Statistics, funded by the Royal Society *Reconstructing the evolutionary history of pathogens using ancient DNA* ☠️🧬🦠🐕🐖🐇 🇬🇧 UK/home students 📍 Centre for Human Genetics, University of Oxford ⏰ Fri, 17 July tinyurl.com/gms-rs-dphil

GMS Royal Society Studentship

DPhil Studentship opportunity for the DPhil Genomic Medicine and Statistics programme

tinyurl.com

Come join our aDNA community at Trinity College Dublin and explore medieval ruminant genomes! Funded PhD studentship in ancient animal genomics at Trinity College Dublin. Deadline 27th May 2026 Please see the information attached for full description and application process.

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I want a "conference" where every academic cooks a dish for everyone and we all talk about our work casually while cooking. People can sous chef for each other. We eat and talk about our work in progress. You submit an abstract and a recipe.

Can safely way this is the craziest and coolest study I have led. We chart the evolution of sheeppox virus, finding it in the Eurasian steppe ~3700 years ago, and also in a LOT of parchment from medieval Europe (made from a range of animals skins!) #aDNA

bioRxiv Genetics@biorxiv-genetic.bsky.social · 6mo ago

3,500 years of sheeppox virus evolution inferred from archaeological and codicological genomes https://www.biorxiv.org/content/10.64898/2026.02.23.707469v1

Why are Dutch people so tall? This has been a long-standing debate in genetics, with earlier studies questioned due to unaccounted for confounding. Great to be involved in a new study (link below) using within-family GWAS; we confirm that height has been under positive selection.

Heritability = a statistical description of sources of interindividual variation in a specific set of people under a specific set of environmental conditions. It doesn't index a fixed underlying feature of human biology. A few lines in this paper acknowledge that but its overall framing may mislead.

Heritability of intrinsic human life span is about 50% when confounding factors are addressed

How heritable is human life span? If genetic heritability is high, longevity genes can reveal aging mechanisms and inform medicine and public health. However, current estimates of heritability are low...

science.org

Our work on the generalizability of polygenic scores (PGS) from the @arbelharpak.bsky.social Lab is now officially out! We examine the accuracy of PGS predictions at the individual level. We make 3 observations that expose gaps in our understanding of PGS “portability.” rdcu.be/e0LAr (1/27)

Three open questions in polygenic score portability

Nature Communications - Genetic predictors of health outcomes often drop in accuracy when applied to people dissimilar to participants of large genetic studies. Here, the authors investigate the...

rdcu.be