Our article examining the effects of chronic #GLP-1 receptor agonist (#semaglutide #ozempic) treatment on the incentive motivational value of a small #food reward and the cue that predicts it is now out in Psychopharmacology. Open access article 👇 link.springer.com/10.1007/s002...

Shelly Flagel@flagel-lab.bsky.social · 8mo ago

Excited to share our new GLP-1 receptor agonist study! Chronic semaglutide potentiates motivation for small food rewards and associated cues, but reduces intake when food is freely available—surprising twist! #GLP-1, #behavior #neuroscience #pharmacology 1/ 🔗 www.biorxiv.org/cgi/content/...

Call for papers for a Special Issue on Big Data, AI and Machine Learning in Addiction research, guest edited by @flagel-lab.bsky.social and @gavanm.bsky.social in @psychopharmacology.bsky.social link.springer.com/collections/...

I was excited to get into the lab today to help out with an experiment...until I realized I now need readers to make out the labels on eppendorfs and pipettes. #oldPIproblems 🔬🧪🔎

In this case, I think the difference is our treatment paradigm. We are using a chronic GLP-1 receptor agonist treatment regimen (similar to that humans experience), whereas most of what we know from the preclinical literature to-date is based on acute treatment.

Drew Schreiner@schreinerdrew.bsky.social · 8mo ago

Huh, interesting! I'm not terribly familiar with the GLP-1 literature, but a quick search suggests cue-induced (and primed) reinstatement of drug seeking is weakened. Wonder what may differ for food reward?

Excited to share our new GLP-1 receptor agonist study! Chronic semaglutide potentiates motivation for small food rewards and associated cues, but reduces intake when food is freely available—surprising twist! #GLP-1, #behavior #neuroscience #pharmacology 1/ 🔗 www.biorxiv.org/cgi/content/...

Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats

Rationale: Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, are increasingly utilized in clinical practice due to their efficacy in promoting sustained weight loss following chr...

biorxiv.org

If you didn’t get a chance to purchase the exclusive 5-year #BlackInNeuro pin last night, I have more with me today! ✨ We’re asking for $15 donations to support BIN programming ❤️ blackinneuro.com/donate Allies are welcome to purchase pins as well 🙌🏾 #SfN25

We ate well last night (in a tent, indoors, with s'mores for dessert), and are energized to talk science today at #SfN2025. Come visit our posters: AA14 this morning Y11, GG13, HH11 this afternoon

Go support all the amazing early career scientists who will be presenting their posters tonight from 6:45 - 8:45 at #SfN2025. This includes Flagel Lab graduate student, Princess Felix, who received a SfN Trainee Professional Development Award. 👏👏👏

We're looking forward to telling you what we've been up to at #sfn25. Flagel Lab posters are all on Monday. Come say hi and speak to these amazing trainees about their research!

Our last virtual open house for the season for our University of Michigan #neuroscience #graduateprogram is Wednesday October 29th, from 7-8:30 PM EST. If you would like to join us, please register by 9 AM Wednesday by scanning the QR code below. 👇

Shelly Flagel@flagel-lab.bsky.social · 10mo ago

Interested in #graduateprograms in #neuroscience? Come learn about our Neuroscience Graduate Program at the University of Michigan. We are offering virtual and in person opportunities to do so in October and November. #SfN2025 #SACNAS #ABRCMS See flyer below and #GoBlue! 👇

Our first virtual open house for the University of Michigan #neuroscience #graduateprogram is tomorrow, October 15th, from 7-8:30 PM EST. If you would like to join us, please register by 9 AM tomorrow using this link: forms.gle/N6LjUrfrr6qL... or scan the QR code below. 👇

Shelly Flagel@flagel-lab.bsky.social · 10mo ago

Interested in #graduateprograms in #neuroscience? Come learn about our Neuroscience Graduate Program at the University of Michigan. We are offering virtual and in person opportunities to do so in October and November. #SfN2025 #SACNAS #ABRCMS See flyer below and #GoBlue! 👇

It was a great day @westernu.ca, and such an honor to be selected by students for the Treva Glazebrook Lecture. Thank you, Kendra Loedige, for being a wonderful host. Great to see you and catch up, @drjkhokhar.bsky.social - thanks for teaching me about academia in Canada. 🤩🇨🇦

Jibran Khokhar@drjkhokhar.bsky.social · 10mo ago

So great to have @flagel-lab.bsky.social give the 2025 Treva Glazebrook Lecture @westernu.ca today! A master-class in the neurobiology of inhibitory control! The lecture is voted on and hosted by neuroscience trainees and they picked a good one! @westernuwin.bsky.social

Interested in #graduateprograms in #neuroscience? Come learn about our Neuroscience Graduate Program at the University of Michigan. We are offering virtual and in person opportunities to do so in October and November. #SfN2025 #SACNAS #ABRCMS See flyer below and #GoBlue! 👇

Published! to NAIL human paraventricular thalamus, we imaged & aligned postmortem human thalamus labeled c calretinin. Finally a gold standard allowing mouse, rat human comparisons onlinelibrary.wiley.com/doi/10.1002/... @ted-satterthwaite.bsky.social @flagel-lab.bsky.social @mikeyassa.bsky.social l

A Combined Neuroanatomy, Ex Vivo Imaging, and Immunohistochemistry Defined MRI Mask for the Human Paraventricular Nucleus of the Thalamus

Existing definitions of the human paraventricular nucleus of the thalamus (PVT) differ between histological and MRI atlases; this study addresses this conflict by leveraging MRI and histology in the ...

onlinelibrary.wiley.com

Always fun to chat with Gill Eapen @ Scientific Sense, and made even more fun with @jbeehner.bsky.social. Learn a bit more about our investigations of sign-/goal-tracking in wild white-faced capuchins, and other related topics. 👇 Audio: podcasts.apple.com/us/podcast/p... Video: youtu.be/NUPI0xNj5U8

Prof. Shelly Flagel and Prof. Jacinta Beehner of the University of Michigan on goal/sign tracking

Podcast Episode · Scientific Sense ® · 09/21/2025 · 57m

podcasts.apple.com

It's been fun. Thanks for hosting us, beautiful Almería, and thanks to everyone at #EBPS2025 for making it a fantastic meeting. Hoping everyone has safe and easy travels. 🤞 See you at #EBPS2027 in Cork!

A brilliant keynote today by @jfcryan.bsky.social at the EBPS meeting on how the gut shapes behavior, including striking causal evidence for microbiome’s role in social behaviors. A masterclass of body-brain complexity! & with an impressive depth of data and the right dose of humor!

Presidents dinner at #EBPS2025. So great to connect with EC members featuring 5 EBPS presidents

Registration booth is open! Get there early to avoid lines and get your awesome swag! ##EBPS2025 @eurbehavpharm.bsky.social

#EBPS2025 we'll be ready for you tomorrow!

Anyone else EXCITED about #EBPS2025? 🎉 Safe travels to everyone coming from around the globe to gather with us in Almeria! 🌎✈️ We still have work to do, but I am proud of our geographic representation at this small meeting. Thank you @connorhaggarty.bsky.social and Margarita Moreno for the image!

The GRFP lives!! (due end of October) www.nsf.gov/funding/oppo...

NSF Graduate Research Fellowship Program (GRFP)

nsf.gov

Did my best to stay positive for our "2025–2026 State of the Lab" address. Here’s to keeping the science (and this awesome crew) afloat.

#FluoresenceFriday capturing the beauty and complexity of midline thalamic nuclei - projections to/from & c-fos (teal). Maybe there is more to the midline thalamus than the PVT? 😉 Thanks to postdoc, Stephanie Desrochers, and undergraduate student, Lea Hsu, for capturing! 🤩

#ThisWeekInNPP Drs. Beehner (@jbeehner.bsky.social) & Flagel (@flagel-lab.bsky.social) of UMichigan call for more experimental & mechanistic field research to provide causal insights & complement lab studies, thereby ⬆️ the translational value of behavioral neuroscience research 🐭🐵🧒

Thanks for the hlighlight @thetransmitter.bsky.social! @jbeehner.bsky.social and I are very excited to further explore some of the ideas put forth in this article.

The Transmitter @thetransmitter.bsky.social · last yr.

𝐖𝐡𝐚𝐭 𝐰𝐞 𝐚𝐫𝐞 𝐫𝐞𝐚𝐝𝐢𝐧𝐠 “Field experimentation enhances translation for behavioral neuroscience” by Jacinta C. Beehner and Shelly B. Flagel @flagel-lab.bsky.social in 𝑁𝑒𝑢𝑟𝑜𝑝𝑠𝑦𝑐ℎ𝑜𝑝ℎ𝑎𝑟𝑚𝑎𝑐𝑜𝑙𝑜𝑔𝑦 doi.org/10.1038/s413... #neuroskyence

Excited to have this little @npp-journal.bsky.social "hot topics" article out with my dear friend and collaborator @jbeehner.bsky.social. Even more excited for the opportunity to jump into field research and explore some of these ideas. www.nature.com/articles/s41...

Neuroscience research and training has taken a $323 million hit in the form of grants rescinded by the U.S. NIH, according to an analysis by @thetransmitter.bsky.social. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/funding/nih-...

NIH cuts quash $323 million for neuroscience research and training

“I am frightened for the state of the future of our field if this isn't reversed rapidly,” says Joshua Gordon, professor of psychiatry at Columbia University and former director of the National…

thetransmitter.org

When NIH fixes exclude you drugmonkey.wordpress.com/2025/06/04/w...

When NIH fixes exclude you

In the midst of all the chaos at NIH of late, there have been two small glimmers of relief. First was the extension of Early Stage Investigator eligibility. The NOT-OD-25-114 [NIH] hereby grants th…

drugmonkey.wordpress.com

Thank you @sfn.org for providing some normalcy during these trying times. 😏 #SFN2025