Everyone reduces dimensions. We reduced cells. Read our latest work on bioRxiv: Quantitative Description of C. elegans mRNA Landscapes From High Coverage Single-Cell Transcriptomes www.biorxiv.org/content/10.6...
Florian Bernard
@florianbrnrd.bsky.social
I put worms in a nanopore sequencer. Genetics, molecular biology and bioinformatics. Astrophotography in my spare time.
We are very excited to present our latest work on bioarxiv: www.biorxiv.org/content/10.6... Where we reveals the hidden depth of scRNA-seq.
Quantitative Description of C. elegans mRNA Landscapes From High Coverage Single Cell Transcriptomes https://www.biorxiv.org/content/10.64898/2026.07.18.734896v1
Quantitative Description of C. elegans mRNA Landscapes From High Coverage Single Cell Transcriptomes https://www.biorxiv.org/content/10.64898/2026.07.18.734896v1
Quantitative Description of C. elegans mRNA Landscapes From High Coverage Single Cell Transcriptomes #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.07.18.734896v1
After a long incubation, it is a huge pleasure to finally share the work of @luzmlopez.bsky.social, Jon Harper and their coauthors: "Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks". @gdsc-sussex.bsky.social www.biorxiv.org/content/10.6...
C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront" www.pnas.org/doi/10.1073/...
From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS
Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...
pnas.org
I just got the notice that all the FlyBase people at Harvard, including me, will be laid off on October 12. I'm devastated.
Preprint on "Improving spliced alignment by modeling splice sites with deep learning". It describes minisplice for modeling splice signals. Minimap2 and miniprot now optionally use the predicted scores to improve spliced alignment. arxiv.org/abs/2506.12986
